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01-05-2010 | Computed Tomography

Radiation exposure and image quality in staged low-dose protocols for coronary dual-source CT angiography: a randomized comparison

Authors: Tobias Pflederer, Josy Jakstat, Mohamed Marwan, Tiziano Schepis, Sven Bachmann, Axel Kuettner, Katharina Anders, Michael Lell, Gerd Muschiol, Dieter Ropers, Werner G. Daniel, Stephan Achenbach

Published in: European Radiology | Issue 5/2010

Abstract

Objective

To evaluate staged low-dose approaches for coronary CT angiography (CTA) in which a standard sequence was added if the low-dose sequence did not allow reliable rule-out of coronary stenosis.

Patients and Methods

A total of 176 consecutive patients referred for dual-source CTA were randomized to three protocols: group 1 using prospective ECG-triggering (100 kV, 330 mAs), group 2 a retrospectively gated “MinDose” sequence (100 kV, 330 mAs) and group 3 a standard spiral sequence (120 kV, 400 mAs). If image quality in low-dose groups 1 or 2 was non-diagnostic, an additional standard CT examination (as in group 3) was performed.

Results

Non-diagnostic image quality was found in 11/56, 4/55, and 2/65 patients (46/896, 4/880 and 3/1,040 coronary segments) in groups 1, 2 and 3, respectively. Median (interquartile ranges) volumes of contrast material, CTDI_vol, DLP and effective dose for low-dose groups 1 and 2 and for standard group 3 were 92.5 (11.3), 75.0 (2.5) and 75.0 (9.0) ml; 8.0 (1.4), 16.8 (4.8) and 48.1 (14.2) mGy; 108.0 (27.3), 246.0 (93.0) and 701.0 (207.8) mGy cm; and 1.5 (0.4), 3.4 (1.3) and 9.8 (2.9) mSv, respectively.

Conclusion

A staged coronary CTA protocol with an initial low-dose approach and addition of a standard sequence—should image quality be too low—can lead to a substantial reduction in radiation exposure.

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Title: Radiation exposure and image quality in staged low-dose protocols for coronary dual-source CT angiography: a randomized comparison
Authors: Tobias Pflederer
Josy Jakstat
Mohamed Marwan
Tiziano Schepis
Sven Bachmann
Axel Kuettner
Katharina Anders
Michael Lell
Gerd Muschiol
Dieter Ropers
Werner G. Daniel
Stephan Achenbach
Publication date: 01-05-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 5/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1645-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Radiation exposure and image quality in staged low-dose protocols for coronary dual-source CT angiography: a randomized comparison

Abstract

Objective

Patients and Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Patients and Methods

Results

Conclusion

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