Skip to main content
Top
Published in: European Radiology 10/2009

Open Access 01-10-2009 | Forensic Medicine

The value of postmortem computed tomography as an alternative for autopsy in trauma victims: a systematic review

Authors: M. Scholing, T. P. Saltzherr, P. H. P. Fung Kon Jin, K. J. Ponsen, J. B. Reitsma, J. S. Lameris, J. C. Goslings

Published in: European Radiology | Issue 10/2009

Login to get access

Abstract

The aim of this study was to assess the role of postmortem computed tomography (PMCT) as an alternative for autopsy in determining the cause of death and the identification of specific injuries in trauma victims. A systematic review was performed by searching the EMBASE and MEDLINE databases. Articles were eligible if they reported both PMCT as well as autopsy findings and included more than one trauma victim. Two reviewers independently assessed the eligibility and quality of the articles. The outcomes were described in terms of the percentage agreement on causes of death and amount of injuries detected. The data extraction and analysis were performed together. Fifteen studies were included describing 244 victims. The median sample size was 13 (range 5–52). The percentage agreement on the cause of death between PMCT and autopsy varied between 46 and 100%. The overall amount of injuries detected on CT ranged from 53 to 100% compared with autopsy. Several studies suggested that PMCT was capable of identifying injuries not detected during normal autopsy. This systematic review provides inconsistent evidence as to whether PMCT is a reliable alternative for autopsy in trauma victims. PMCT has promising features in postmortem examination suggesting PMCT is a good alternative for a refused autopsy or a good adjunct to autopsy because it detects extra injuries overseen during autopsies. To examine the value of PMCT in trauma victims there is a need for well-designed and larger prospective studies.
Literature
2.
go back to reference Mock C, Lormand JD, Goosen J, Joshipura M, Peden M (2004) Guidelines for essential trauma care. World Health Organization, Geneva Mock C, Lormand JD, Goosen J, Joshipura M, Peden M (2004) Guidelines for essential trauma care. World Health Organization, Geneva
3.
go back to reference Baker CC, Oppenheimer L, Stephens B, Lewis FR, Trunkey DD (1980) Epidemiology of trauma deaths. Am J Surg 140:144–150PubMedCrossRef Baker CC, Oppenheimer L, Stephens B, Lewis FR, Trunkey DD (1980) Epidemiology of trauma deaths. Am J Surg 140:144–150PubMedCrossRef
4.
go back to reference Trunkey DD (1983) Trauma. Accidental and intentional injuries account for more years of life lost in the US than cancer and heart disease. Among the prescribed remedies are improved preventive efforts, speedier surgery and further research. Sci Am 249:28–35PubMedCrossRef Trunkey DD (1983) Trauma. Accidental and intentional injuries account for more years of life lost in the US than cancer and heart disease. Among the prescribed remedies are improved preventive efforts, speedier surgery and further research. Sci Am 249:28–35PubMedCrossRef
5.
go back to reference Teixeira PG, Inaba K, Hadjizacharia P, Brown C, Salim A, Rhee P, Browder T, Noguchi TT, Demetriades D (2007) Preventable or potentially preventable mortality at a mature trauma center. J Trauma 63:1338–1346PubMedCrossRef Teixeira PG, Inaba K, Hadjizacharia P, Brown C, Salim A, Rhee P, Browder T, Noguchi TT, Demetriades D (2007) Preventable or potentially preventable mortality at a mature trauma center. J Trauma 63:1338–1346PubMedCrossRef
6.
go back to reference Hijar M, Chu LD, Kraus JF (2000) Cross-national comparison of injury mortality: Los Angeles County, California and Mexico City, Mexico. Int J Epidemiol 29:715–721PubMedCrossRef Hijar M, Chu LD, Kraus JF (2000) Cross-national comparison of injury mortality: Los Angeles County, California and Mexico City, Mexico. Int J Epidemiol 29:715–721PubMedCrossRef
7.
go back to reference Cothren CC, Moore EE, Hedegaard HB, Meng K (2007) Epidemiology of urban trauma deaths: a comprehensive reassessment 10 years later. World J Surg 31:1507–1511PubMedCrossRef Cothren CC, Moore EE, Hedegaard HB, Meng K (2007) Epidemiology of urban trauma deaths: a comprehensive reassessment 10 years later. World J Surg 31:1507–1511PubMedCrossRef
8.
go back to reference Soreide K, Kruger AJ, Vardal AL, Ellingsen CL, Soreide E, Lossius HM (2007) Epidemiology and contemporary patterns of trauma deaths: changing place, similar pace, older face. World J Surg 31:2092–2103PubMedCrossRef Soreide K, Kruger AJ, Vardal AL, Ellingsen CL, Soreide E, Lossius HM (2007) Epidemiology and contemporary patterns of trauma deaths: changing place, similar pace, older face. World J Surg 31:2092–2103PubMedCrossRef
9.
go back to reference Yagmur Y, Kiraz M, Kara IH (1999) Looking at trauma and deaths: Diyarbakir city in Turkey. Injury 30:111–114PubMedCrossRef Yagmur Y, Kiraz M, Kara IH (1999) Looking at trauma and deaths: Diyarbakir city in Turkey. Injury 30:111–114PubMedCrossRef
10.
go back to reference Tien HC, Spencer F, Tremblay LN, Rizoli SB, Brenneman FD (2007) Preventable deaths from hemorrhage at a level I Canadian trauma center. J Trauma 62:142–146PubMedCrossRef Tien HC, Spencer F, Tremblay LN, Rizoli SB, Brenneman FD (2007) Preventable deaths from hemorrhage at a level I Canadian trauma center. J Trauma 62:142–146PubMedCrossRef
11.
go back to reference Stewart RM, Myers JG, Dent DL, Ermis P, Gray GA, Villarreal R, Blow O, Woods B, McFarland M, Garavaglia J, Root HD, Pruitt BA Jr (2003) Seven hundred fifty-three consecutive deaths in a level I trauma center: the argument for injury prevention. J Trauma 54:66–70PubMedCrossRef Stewart RM, Myers JG, Dent DL, Ermis P, Gray GA, Villarreal R, Blow O, Woods B, McFarland M, Garavaglia J, Root HD, Pruitt BA Jr (2003) Seven hundred fifty-three consecutive deaths in a level I trauma center: the argument for injury prevention. J Trauma 54:66–70PubMedCrossRef
12.
go back to reference Berget E, Ramnefjell M, Svendsen EB, Bertelsen BI, Maehle BO, Svendsen E (2007) [Decline in hospital autopsies.]. Tidsskr Nor Laegeforen 127:2800–2802PubMed Berget E, Ramnefjell M, Svendsen EB, Bertelsen BI, Maehle BO, Svendsen E (2007) [Decline in hospital autopsies.]. Tidsskr Nor Laegeforen 127:2800–2802PubMed
13.
go back to reference Fung Kon Jin PH, Klaver JF, Maes A, Ponsen KJ, Das C, Goslings JC (2008) Autopsies following death due to traumatic injuries in The Netherlands: an evaluation of current practice. Injury 39:83–89PubMedCrossRef Fung Kon Jin PH, Klaver JF, Maes A, Ponsen KJ, Das C, Goslings JC (2008) Autopsies following death due to traumatic injuries in The Netherlands: an evaluation of current practice. Injury 39:83–89PubMedCrossRef
14.
go back to reference Loughrey MB, McCluggage WG, Toner PG (2000) The declining autopsy rate and clinicians’ attitudes. Ulster Med J 69:83–89PubMed Loughrey MB, McCluggage WG, Toner PG (2000) The declining autopsy rate and clinicians’ attitudes. Ulster Med J 69:83–89PubMed
16.
go back to reference Ong AW, Cohn SM, Cohn KA, Jaramillo DH, Parbhu R, McKenney MG, Barquist ES, Bell MD (2002) Unexpected findings in trauma patients dying in the intensive care unit: results of 153 consecutive autopsies. J Am Coll Surg 194:401–406PubMedCrossRef Ong AW, Cohn SM, Cohn KA, Jaramillo DH, Parbhu R, McKenney MG, Barquist ES, Bell MD (2002) Unexpected findings in trauma patients dying in the intensive care unit: results of 153 consecutive autopsies. J Am Coll Surg 194:401–406PubMedCrossRef
17.
go back to reference Hodgson NF, Stewart TC, Girotti MJ (2000) Autopsies and death certification in deaths due to blunt trauma: what are we missing? Can J Surg 43:130–136PubMed Hodgson NF, Stewart TC, Girotti MJ (2000) Autopsies and death certification in deaths due to blunt trauma: what are we missing? Can J Surg 43:130–136PubMed
18.
go back to reference Bolliger SA, Thali MJ, Ross S, Buck U, Naether S, Vock P (2008) Virtual autopsy using imaging: bridging radiologic and forensic sciences. A review of the Virtopsy and similar projects. Eur Radiol 18:273–282PubMedCrossRef Bolliger SA, Thali MJ, Ross S, Buck U, Naether S, Vock P (2008) Virtual autopsy using imaging: bridging radiologic and forensic sciences. A review of the Virtopsy and similar projects. Eur Radiol 18:273–282PubMedCrossRef
19.
go back to reference Ljung P, Winskog C, Persson A, Lundstrom C, Ynnerman A (2006) Full body virtual autopsies using a state-of-the-art volume rendering pipeline. IEEE Trans Vis Comput Graph 12:869–876PubMedCrossRef Ljung P, Winskog C, Persson A, Lundstrom C, Ynnerman A (2006) Full body virtual autopsies using a state-of-the-art volume rendering pipeline. IEEE Trans Vis Comput Graph 12:869–876PubMedCrossRef
20.
go back to reference O’Donnell C, Rotman A, Collett S, Woodford N (2008) Current status of routine post-mortem CT in Melbourne, Australia. Forensic Sci Med Pathol 3:226–232CrossRef O’Donnell C, Rotman A, Collett S, Woodford N (2008) Current status of routine post-mortem CT in Melbourne, Australia. Forensic Sci Med Pathol 3:226–232CrossRef
21.
go back to reference Whiting PF, Weswood ME, Rutjes AW, Reitsma JB, Bossuyt PN, Kleijnen J (2006) Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. BMC Med Res Methodol 6:9PubMedCrossRef Whiting PF, Weswood ME, Rutjes AW, Reitsma JB, Bossuyt PN, Kleijnen J (2006) Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. BMC Med Res Methodol 6:9PubMedCrossRef
22.
go back to reference Brown LD, Cai TT, Dasgupta A (2001) Interval estimation for a binomial proportion. Stat Sci 16:101–133 Brown LD, Cai TT, Dasgupta A (2001) Interval estimation for a binomial proportion. Stat Sci 16:101–133
23.
go back to reference Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560PubMedCrossRef Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560PubMedCrossRef
24.
go back to reference Aghayev E, Christe A, Sonnenschein M, Yen K, Jackowski C, Thali MJ, Dirnhofer R, Vock P (2008) Postmortem imaging of blunt chest trauma using CT and MRI: comparison with autopsy. J Thorac Imaging 23:20–27PubMedCrossRef Aghayev E, Christe A, Sonnenschein M, Yen K, Jackowski C, Thali MJ, Dirnhofer R, Vock P (2008) Postmortem imaging of blunt chest trauma using CT and MRI: comparison with autopsy. J Thorac Imaging 23:20–27PubMedCrossRef
25.
go back to reference Andenmatten MA, Thali MJ, Kneubuehl BP, Oesterhelweg L, Ross S, Spendlove D, Bolliger SA (2008) Gunshot injuries detected by post-mortem multislice computed tomography (MSCT): A feasibility study. Leg Med (Tokyo) 10:287–292 Andenmatten MA, Thali MJ, Kneubuehl BP, Oesterhelweg L, Ross S, Spendlove D, Bolliger SA (2008) Gunshot injuries detected by post-mortem multislice computed tomography (MSCT): A feasibility study. Leg Med (Tokyo) 10:287–292
26.
go back to reference Christe A, Aghayev E, Jackowski C, Thali MJ, Vock P (2008) Drowning—post-mortem imaging findings by computed tomography. Eur Radiol 18:283–290PubMedCrossRef Christe A, Aghayev E, Jackowski C, Thali MJ, Vock P (2008) Drowning—post-mortem imaging findings by computed tomography. Eur Radiol 18:283–290PubMedCrossRef
27.
go back to reference Donchin Y, Rivkind AI, Bar-Ziv J, Hiss J, Almog J, Drescher M (1994) Utility of postmortem computed tomography in trauma victims. J Trauma 37:552–555PubMedCrossRef Donchin Y, Rivkind AI, Bar-Ziv J, Hiss J, Almog J, Drescher M (1994) Utility of postmortem computed tomography in trauma victims. J Trauma 37:552–555PubMedCrossRef
28.
go back to reference Harcke HT, Levy AD, Abbott RM, Mallak CT, Getz JM, Champion HR, Pearse L (2007) Autopsy radiography: digital radiographs (DR) vs multidetector computed tomography (MDCT) in high-velocity gunshot-wound victims. Am J Forensic Med Pathol 28:13–19PubMedCrossRef Harcke HT, Levy AD, Abbott RM, Mallak CT, Getz JM, Champion HR, Pearse L (2007) Autopsy radiography: digital radiographs (DR) vs multidetector computed tomography (MDCT) in high-velocity gunshot-wound victims. Am J Forensic Med Pathol 28:13–19PubMedCrossRef
29.
go back to reference Hoey BA, Cipolla J, Grossman MD, McQuay N, Shukla PR, Stawicki SP, Stehly C, Hoff WS (2007) Postmortem computed tomography, “CATopsy", predicts cause of death in trauma patients. J Trauma 63:979–985PubMedCrossRef Hoey BA, Cipolla J, Grossman MD, McQuay N, Shukla PR, Stawicki SP, Stehly C, Hoff WS (2007) Postmortem computed tomography, “CATopsy", predicts cause of death in trauma patients. J Trauma 63:979–985PubMedCrossRef
30.
go back to reference Leth PM (2008) The use of CT scanning in forensic autopsy. Forensic Sci Med Pathol 3:65–69 Leth PM (2008) The use of CT scanning in forensic autopsy. Forensic Sci Med Pathol 3:65–69
31.
go back to reference Levy AD, Abbott RM, Mallak CT, Getz JM, Harcke HT, Champion HR, Pearse LA (2006) Virtual autopsy: preliminary experience in high-velocity gunshot wound victims. Radiology 240:522–528PubMedCrossRef Levy AD, Abbott RM, Mallak CT, Getz JM, Harcke HT, Champion HR, Pearse LA (2006) Virtual autopsy: preliminary experience in high-velocity gunshot wound victims. Radiology 240:522–528PubMedCrossRef
32.
go back to reference Levy G, Goldstein L, Blachar A, Apter S, Barenboim E, Bar-Dayan Y, Shamis A, Atar E (2007) Postmortem computed tomography in victims of military air mishaps: radiological-pathological correlation of CT findings. Isr Med Assoc J 9:699–702PubMed Levy G, Goldstein L, Blachar A, Apter S, Barenboim E, Bar-Dayan Y, Shamis A, Atar E (2007) Postmortem computed tomography in victims of military air mishaps: radiological-pathological correlation of CT findings. Isr Med Assoc J 9:699–702PubMed
33.
go back to reference Paperno S, Riepert T, Krug B, Rothschild MA, Schultes A, Staak M, Lackner L (2005) [Value of postmortem computed tomography in comparison to autopsy]. Rofo 177:130–136PubMed Paperno S, Riepert T, Krug B, Rothschild MA, Schultes A, Staak M, Lackner L (2005) [Value of postmortem computed tomography in comparison to autopsy]. Rofo 177:130–136PubMed
34.
go back to reference Rutty GN, Robinson CE, BouHaidar R, Jeffery AJ, Morgan B (2007) The role of mobile computed tomography in mass fatality incidents. J Forensic Sci 52:1343–1349PubMed Rutty GN, Robinson CE, BouHaidar R, Jeffery AJ, Morgan B (2007) The role of mobile computed tomography in mass fatality incidents. J Forensic Sci 52:1343–1349PubMed
35.
go back to reference Thali MJ, Yen K, Schweitzer W, Vock P, Boesch C, Ozdoba C, Schroth G, Ith M, Sonnenschein M, Doernhoefer T, Scheurer E, Plattner T, Dirnhofer R (2003) Virtopsy, a new imaging horizon in forensic pathology: virtual autopsy by postmortem multislice computed tomography (MSCT) and magnetic resonance imaging (MRI)—a feasibility study. J Forensic Sci 48:386–403PubMed Thali MJ, Yen K, Schweitzer W, Vock P, Boesch C, Ozdoba C, Schroth G, Ith M, Sonnenschein M, Doernhoefer T, Scheurer E, Plattner T, Dirnhofer R (2003) Virtopsy, a new imaging horizon in forensic pathology: virtual autopsy by postmortem multislice computed tomography (MSCT) and magnetic resonance imaging (MRI)—a feasibility study. J Forensic Sci 48:386–403PubMed
36.
go back to reference Yen K, Thali MJ, Aghayev E, Jackowski C, Schweitzer W, Boesch C, Vock P, Dirnhofer R, Sonnenschein M (2005) Strangulation signs: initial correlation of MRI, MSCT, and forensic neck findings. J Magn Reson Imaging 22:501–510PubMedCrossRef Yen K, Thali MJ, Aghayev E, Jackowski C, Schweitzer W, Boesch C, Vock P, Dirnhofer R, Sonnenschein M (2005) Strangulation signs: initial correlation of MRI, MSCT, and forensic neck findings. J Magn Reson Imaging 22:501–510PubMedCrossRef
37.
go back to reference Yen K, Sonnenschein M, Thali MJ, Ozdoba C, Weis J, Zwygart K, Aghayev E, Jackowski C, Dirnhofer R (2005) Postmortem multislice computed tomography and magnetic resonance imaging of odontoid fractures, atlantoaxial distractions and ascending medullary edema. Int J Legal Med 119:129–136PubMedCrossRef Yen K, Sonnenschein M, Thali MJ, Ozdoba C, Weis J, Zwygart K, Aghayev E, Jackowski C, Dirnhofer R (2005) Postmortem multislice computed tomography and magnetic resonance imaging of odontoid fractures, atlantoaxial distractions and ascending medullary edema. Int J Legal Med 119:129–136PubMedCrossRef
38.
go back to reference Yen K, Lovblad KO, Scheurer E, Ozdoba C, Thali MJ, Aghayev E, Jackowski C, Anon J, Frickey N, Zwygart K, Weis J, Dirnhofer R (2007) Post-mortem forensic neuroimaging: correlation of MSCT and MRI findings with autopsy results. Forensic Sci Int 173:21–35PubMedCrossRef Yen K, Lovblad KO, Scheurer E, Ozdoba C, Thali MJ, Aghayev E, Jackowski C, Anon J, Frickey N, Zwygart K, Weis J, Dirnhofer R (2007) Post-mortem forensic neuroimaging: correlation of MSCT and MRI findings with autopsy results. Forensic Sci Int 173:21–35PubMedCrossRef
39.
go back to reference Hayakawa M, Yamamoto S, Motani H, Yajima D, Sato Y, Iwase H (2006) Does imaging technology overcome problems of conventional postmortem examination? A trial of computed tomography imaging for postmortem examination. Int J Legal Med 120:24–26PubMedCrossRef Hayakawa M, Yamamoto S, Motani H, Yajima D, Sato Y, Iwase H (2006) Does imaging technology overcome problems of conventional postmortem examination? A trial of computed tomography imaging for postmortem examination. Int J Legal Med 120:24–26PubMedCrossRef
40.
go back to reference Levy AD, Harcke HT, Getz JM, Mallak CT, Caruso JL, Pearse L, Frazier AA, Galvin JR (2007) Virtual autopsy: two- and three-dimensional multidetector CT findings in drowning with autopsy comparison. Radiology 243:862–868PubMedCrossRef Levy AD, Harcke HT, Getz JM, Mallak CT, Caruso JL, Pearse L, Frazier AA, Galvin JR (2007) Virtual autopsy: two- and three-dimensional multidetector CT findings in drowning with autopsy comparison. Radiology 243:862–868PubMedCrossRef
41.
go back to reference Poulsen K, Simonsen J (2007) Computed tomography as routine in connection with medico-legal autopsies. Forensic Sci Int 171:190–197PubMedCrossRef Poulsen K, Simonsen J (2007) Computed tomography as routine in connection with medico-legal autopsies. Forensic Sci Int 171:190–197PubMedCrossRef
42.
go back to reference Yamazaki K, Shiotani S, Ohashi N, Doi M, Kikuchi K, Nagata C, Honda K (2006) Comparison between computed tomography (CT) and autopsy findings in cases of abdominal injury and disease. Forensic Sci Int 162:163–166PubMedCrossRef Yamazaki K, Shiotani S, Ohashi N, Doi M, Kikuchi K, Nagata C, Honda K (2006) Comparison between computed tomography (CT) and autopsy findings in cases of abdominal injury and disease. Forensic Sci Int 162:163–166PubMedCrossRef
43.
go back to reference Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174PubMedCrossRef Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174PubMedCrossRef
44.
go back to reference Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF (1999) Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of reporting of meta-analyses. Lancet 354:1896–1900PubMedCrossRef Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF (1999) Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of reporting of meta-analyses. Lancet 354:1896–1900PubMedCrossRef
45.
go back to reference AAAM Committee on Injury Scaling (1998) Abbreviated injury scale (AIS) (1990 revision)—update 98. Association for the Advancement of Automotive Medicin, Des Plains, IL AAAM Committee on Injury Scaling (1998) Abbreviated injury scale (AIS) (1990 revision)—update 98. Association for the Advancement of Automotive Medicin, Des Plains, IL
46.
go back to reference Jackowski C, Sonnenschein M, Thali MJ, Aghayev E, von AG, Yen K, Dirnhofer R, Vock P (2005) Virtopsy: postmortem minimally invasive angiography using cross section techniques—implementation and preliminary results. J Forensic Sci 50:1175–1186PubMedCrossRef Jackowski C, Sonnenschein M, Thali MJ, Aghayev E, von AG, Yen K, Dirnhofer R, Vock P (2005) Virtopsy: postmortem minimally invasive angiography using cross section techniques—implementation and preliminary results. J Forensic Sci 50:1175–1186PubMedCrossRef
Metadata
Title
The value of postmortem computed tomography as an alternative for autopsy in trauma victims: a systematic review
Authors
M. Scholing
T. P. Saltzherr
P. H. P. Fung Kon Jin
K. J. Ponsen
J. B. Reitsma
J. S. Lameris
J. C. Goslings
Publication date
01-10-2009
Publisher
Springer-Verlag
Published in
European Radiology / Issue 10/2009
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-009-1440-4

Other articles of this Issue 10/2009

European Radiology 10/2009 Go to the issue