Skip to main content
Top
Published in: European Radiology 2/2006

01-02-2006 | Musculoskeletal

Cervical spine and crystal-associated diseases: imaging findings

Authors: Antoine Feydy, Frédéric Lioté, Robert Carlier, Alain Chevrot, Jean-Luc Drapé

Published in: European Radiology | Issue 2/2006

Login to get access

Abstract

The cervical spine may be specifically involved in crystal-associated arthropathies. In this article, we focus on the three common crystals and diseases: hydroxyapatite crystal deposition disease, calcium pyrophosphate dihydrate (CPPD) deposition disease, and monosodium urate crystals (gout). The cervical involvement in crystal-associated diseases may provoke a misleading clinical presentation with acute neck pain, fever, or neurological symptoms. Imaging allows an accurate diagnosis in typical cases with calcific deposits and destructive lesions of the discs and joints. Most of the cases are related to CPPD or hydroxyapatite crystal deposition; gout is much less common.
Literature
1.
go back to reference Rubenstein J, Pritzker KP (1989) Crystal-associated arthropathies. Am J Roentgenol 152:685–695 Rubenstein J, Pritzker KP (1989) Crystal-associated arthropathies. Am J Roentgenol 152:685–695
2.
go back to reference Uri DS, Dalinka MK (1996) Imaging of arthropathies. Crystal disease. Radiol Clin North Am 34:359–374 Uri DS, Dalinka MK (1996) Imaging of arthropathies. Crystal disease. Radiol Clin North Am 34:359–374
3.
go back to reference Steinbach LS (2004) Calcium pyrophosphate dihydrate and calcium hydroxyapatite crystal deposition diseases: imaging perspectives. Radiol Clin North Am 42:185–205 Steinbach LS (2004) Calcium pyrophosphate dihydrate and calcium hydroxyapatite crystal deposition diseases: imaging perspectives. Radiol Clin North Am 42:185–205
4.
go back to reference Garcia GM, McCord GC, Kumar R (2003) Hydroxyapatite crystal deposition disease. Semin Musculoskelet Radiol 7:187–193 Garcia GM, McCord GC, Kumar R (2003) Hydroxyapatite crystal deposition disease. Semin Musculoskelet Radiol 7:187–193
5.
go back to reference Bencardino JT, Hassankhani A (2003) Calcium pyrophosphate dihydrate crystal deposition disease. Semin Musculoskelet Radiol 7:175–185 Bencardino JT, Hassankhani A (2003) Calcium pyrophosphate dihydrate crystal deposition disease. Semin Musculoskelet Radiol 7:175–185
6.
go back to reference Ring D, Vaccaro AR, Scuderi G, Pathria MN, Garfin SR (1994) Acute calcific retropharyngeal tendinitis. J Bone Jt Surg 76-A:1636–1642 Ring D, Vaccaro AR, Scuderi G, Pathria MN, Garfin SR (1994) Acute calcific retropharyngeal tendinitis. J Bone Jt Surg 76-A:1636–1642
7.
go back to reference Haun CL (1978) Retropharyngeal tendinitis. Am J Roentgenol 130:1137–1140 Haun CL (1978) Retropharyngeal tendinitis. Am J Roentgenol 130:1137–1140
8.
go back to reference Newmark H III, Forrester DM, Brown JC, Robinson A, Oiken SM, Bledsoe R (1978) Calcific tendinitis of the neck. Radiology 128:355–358 Newmark H III, Forrester DM, Brown JC, Robinson A, Oiken SM, Bledsoe R (1978) Calcific tendinitis of the neck. Radiology 128:355–358
9.
go back to reference Hall FM, Docken WP, Curtis HW (1986) Calcific tendinitis of the longus coli: diagnosis by CT. Am J Roentgenol 147:742–743 Hall FM, Docken WP, Curtis HW (1986) Calcific tendinitis of the longus coli: diagnosis by CT. Am J Roentgenol 147:742–743
10.
go back to reference Newmark H III, Blackford D, Roberts D, Chakmakian V, Adler J (1986) Computed tomography of acute cervical spine tendinitis. J Comput Tomogr 10:373–375 Newmark H III, Blackford D, Roberts D, Chakmakian V, Adler J (1986) Computed tomography of acute cervical spine tendinitis. J Comput Tomogr 10:373–375
11.
go back to reference Eastwood JD, Hudgins PA, Malone D (1998) Retropharyngeal effusion in acute calcific prevertebral tendinitis: diagnosis with CT and MR imaging. Am J Neuroradiol 19:1789–1792 Eastwood JD, Hudgins PA, Malone D (1998) Retropharyngeal effusion in acute calcific prevertebral tendinitis: diagnosis with CT and MR imaging. Am J Neuroradiol 19:1789–1792
12.
go back to reference Bouvet J-P, LeParc J-M, Michalski B, Benlahrache C, Auquier L (1985) Acute neck pain due to calcifications surrounding the odontoid process: the crowned dens syndrome. Arthritis Rheum 28:1417–1420 Bouvet J-P, LeParc J-M, Michalski B, Benlahrache C, Auquier L (1985) Acute neck pain due to calcifications surrounding the odontoid process: the crowned dens syndrome. Arthritis Rheum 28:1417–1420
13.
go back to reference Ziza JM, Bouvet JP, Auquier L (1982) Cervicalgie aiguë sous-occipitale d’origine calcique. Rev Rhum 49:549–551 Ziza JM, Bouvet JP, Auquier L (1982) Cervicalgie aiguë sous-occipitale d’origine calcique. Rev Rhum 49:549–551
14.
go back to reference Malca S, Roche PH, Pellet W, Combalbert A (1995) Crowned dens syndrome: a manifestation of hydroxyapatite rheumatism. Acta Neurochir 135:126–130 Malca S, Roche PH, Pellet W, Combalbert A (1995) Crowned dens syndrome: a manifestation of hydroxyapatite rheumatism. Acta Neurochir 135:126–130
15.
go back to reference Resnick D, Pineda C (1984) Vertebral involvement in calcium pyrophosphate dihydrate crystal deposition disease. Radiographic-pathological correlation. Radiology 153:55–60 Resnick D, Pineda C (1984) Vertebral involvement in calcium pyrophosphate dihydrate crystal deposition disease. Radiographic-pathological correlation. Radiology 153:55–60
16.
go back to reference Chanchairujira K, Chung CB, Kim JY, Papakonstantinou O, Lee MH, Clopton P, Resnick D (2004) Intervertebral disk calcification of the spine in an elderly population: radiographic prevalence, location, and distribution and correlation with spinal degeneration. Radiology 230:499–503 Chanchairujira K, Chung CB, Kim JY, Papakonstantinou O, Lee MH, Clopton P, Resnick D (2004) Intervertebral disk calcification of the spine in an elderly population: radiographic prevalence, location, and distribution and correlation with spinal degeneration. Radiology 230:499–503
17.
go back to reference Benoist M, Bloch-Michel H, Kahn MF, Polack Y (1980) Les manifestations vertébrales de la chondrocalcinose articulaire. A propos de 80 observations. Rev Rhum Mal Osteo-articul 47:337–343 Benoist M, Bloch-Michel H, Kahn MF, Polack Y (1980) Les manifestations vertébrales de la chondrocalcinose articulaire. A propos de 80 observations. Rev Rhum Mal Osteo-articul 47:337–343
18.
go back to reference Ellman MH, Vazquez T, Ferguson L, Mandel N (1978) Calcium pyrophosphate deposition in ligamentum flavum. Arthritis Rheum 21:611–613 Ellman MH, Vazquez T, Ferguson L, Mandel N (1978) Calcium pyrophosphate deposition in ligamentum flavum. Arthritis Rheum 21:611–613
19.
go back to reference Iwasaki Y, Akino M, Abe H et al (1983) Calcification of the ligamentum flavum of the cervical spine. Report of four cases. J Neurosurg 59:531–534 Iwasaki Y, Akino M, Abe H et al (1983) Calcification of the ligamentum flavum of the cervical spine. Report of four cases. J Neurosurg 59:531–534
20.
go back to reference Baba H, Maezawa Y, Kawahara N, Tomita K, Furusawa N, Imura S (1993) Calcium crystal deposition in the ligamentum flavum of the cervical spine. Spine 18:2174–2181 Baba H, Maezawa Y, Kawahara N, Tomita K, Furusawa N, Imura S (1993) Calcium crystal deposition in the ligamentum flavum of the cervical spine. Spine 18:2174–2181
21.
go back to reference Kawano N, Matsumo T, Miyazawa S et al (1988) Calcium pyrophosphate dihydrate crystal deposition disease in the cervical ligamentum flavum. J Neurosurg 68:613–620 Kawano N, Matsumo T, Miyazawa S et al (1988) Calcium pyrophosphate dihydrate crystal deposition disease in the cervical ligamentum flavum. J Neurosurg 68:613–620
22.
go back to reference Chazerain P, Kaplan G (1990) Arthropathies destructrices dégénératives de la charnière cervico-occipitale. Rev Rhum Mal Osteo-articul 57:549–552 Chazerain P, Kaplan G (1990) Arthropathies destructrices dégénératives de la charnière cervico-occipitale. Rev Rhum Mal Osteo-articul 57:549–552
23.
go back to reference Brem JB (1982) Vertebral ankylosis in a patient with hereditary chondrocalcinosis: a chance association? Arthritis Rheum 25:1257–1263 Brem JB (1982) Vertebral ankylosis in a patient with hereditary chondrocalcinosis: a chance association? Arthritis Rheum 25:1257–1263
24.
go back to reference Cottin S, LeGall G, Lanoiselee JM, Rault D (1980) Les pseudo-spondylodiscites de la chondrocalcinose articulaire diffuse. Nouv Presse Méd 9:1827–1830 Cottin S, LeGall G, Lanoiselee JM, Rault D (1980) Les pseudo-spondylodiscites de la chondrocalcinose articulaire diffuse. Nouv Presse Méd 9:1827–1830
25.
go back to reference Lambert P, Bacques O, Marteau J, Lamotte JC, de Bary A, Grange V (1982) Spondylodiscite ou pseudo-spondylodiscite plurifocale et chondrocalcinose articulaire. Rev Rhum Mal Osteo-articul 49:701–706 Lambert P, Bacques O, Marteau J, Lamotte JC, de Bary A, Grange V (1982) Spondylodiscite ou pseudo-spondylodiscite plurifocale et chondrocalcinose articulaire. Rev Rhum Mal Osteo-articul 49:701–706
26.
go back to reference Fye KH, Weinstein PR, Donald F (1999) Compressive cervical myelopathy due to calcium pyrophosphate dihydrate deposition disease. Report of a case and review of the literature. Arch Intern Med 159:189–193 Fye KH, Weinstein PR, Donald F (1999) Compressive cervical myelopathy due to calcium pyrophosphate dihydrate deposition disease. Report of a case and review of the literature. Arch Intern Med 159:189–193
27.
go back to reference Dirheimer Y, Bensimon C, Christmann D, Wackenheim C (1983) Syndesmoodontoid joint and calcium pyrophosphate dihydrate deposition disease (CPPD). Neuroradiology 25:319–321 Dirheimer Y, Bensimon C, Christmann D, Wackenheim C (1983) Syndesmoodontoid joint and calcium pyrophosphate dihydrate deposition disease (CPPD). Neuroradiology 25:319–321
28.
go back to reference Dirheimer Y, Wackenheim C, Dietemann JL (1985) Calcification of the transverse ligament in calcium dihydrate deposition disease (CPPD). Neuroradiology 27:87 Dirheimer Y, Wackenheim C, Dietemann JL (1985) Calcification of the transverse ligament in calcium dihydrate deposition disease (CPPD). Neuroradiology 27:87
29.
go back to reference Baysal T, Baysal O, Kutlu R, Karaman I, Mizrak B (2000) The crowned dens syndrome: a rare form of calcium pyrophosphate deposition disease. Eur Radiol 10:1003–1005 Baysal T, Baysal O, Kutlu R, Karaman I, Mizrak B (2000) The crowned dens syndrome: a rare form of calcium pyrophosphate deposition disease. Eur Radiol 10:1003–1005
30.
go back to reference Aouba A, Lidove O, Gepner P et al (2003) Crowned dens syndrome: three new cases. Rev Méd Intern 24:49–54 Aouba A, Lidove O, Gepner P et al (2003) Crowned dens syndrome: three new cases. Rev Méd Intern 24:49–54
31.
go back to reference Kakitsubata Y, Boutin RD, Theodorou DJ et al (2000) Calcium pyrophosphate dihydrate crystal deposition in and around the atlantoaxial joint: association with type 2 odontoid fractures in nine patients. Radiology 216:213–219 Kakitsubata Y, Boutin RD, Theodorou DJ et al (2000) Calcium pyrophosphate dihydrate crystal deposition in and around the atlantoaxial joint: association with type 2 odontoid fractures in nine patients. Radiology 216:213–219
32.
go back to reference El-Khoury GY, Tozzi JE, Clark CR, Foucar E, Menezes AH, Smoker WRK (1985) Massive calcium pyrophosphate crystal deposition at the craniovertebral junction. Am J Roentgenol 145:777–778 El-Khoury GY, Tozzi JE, Clark CR, Foucar E, Menezes AH, Smoker WRK (1985) Massive calcium pyrophosphate crystal deposition at the craniovertebral junction. Am J Roentgenol 145:777–778
33.
go back to reference Assaker R, Louis E, Boutry N, Bera-Louville A, Lejeune JP (2001) Foramen magnum syndrome secondary to calcium pyrophosphate crystal deposition in the transverse ligament of the atlas. Spine 26:1396–1400 Assaker R, Louis E, Boutry N, Bera-Louville A, Lejeune JP (2001) Foramen magnum syndrome secondary to calcium pyrophosphate crystal deposition in the transverse ligament of the atlas. Spine 26:1396–1400
34.
go back to reference Kobayashi Y, Mochida J, Saito I, Matui S, Toh E (2001) Calcification of the alar ligament of the cervical spine: imaging findings and clinical course. Skelet Radiol 30:295–297 Kobayashi Y, Mochida J, Saito I, Matui S, Toh E (2001) Calcification of the alar ligament of the cervical spine: imaging findings and clinical course. Skelet Radiol 30:295–297
35.
go back to reference Sato R, Takahashi M, Yamashita Y et al (1992) Calcium crystal deposition in cervical ligamentum flavum: CT and MR findings. J Comput Assist Tomogr 16:352–355 Sato R, Takahashi M, Yamashita Y et al (1992) Calcium crystal deposition in cervical ligamentum flavum: CT and MR findings. J Comput Assist Tomogr 16:352–355
36.
go back to reference Brown TR, Quinn SF, D’Agostino AN (1991) Deposition of calcium pyrophosphate dihydrate crystals in the ligamentum flavum: evaluation with MR imaging and CT. Radiology 178:871–873 Brown TR, Quinn SF, D’Agostino AN (1991) Deposition of calcium pyrophosphate dihydrate crystals in the ligamentum flavum: evaluation with MR imaging and CT. Radiology 178:871–873
37.
go back to reference Zapletal J, Hekster RE, Straver JS, Wilmink JT (1995) Atlanto-odontoid osteoarthritis. Appearance and prevalence at computed tomography. Spine 20:49–53 Zapletal J, Hekster RE, Straver JS, Wilmink JT (1995) Atlanto-odontoid osteoarthritis. Appearance and prevalence at computed tomography. Spine 20:49–53
38.
go back to reference Prost A, Tanguy G, Audran M, Cottin S, Calvez A, Elie JP (1982) Arthroses érosives atloïdo-axoïdiennes. Rev Rhum 49:365–369 Prost A, Tanguy G, Audran M, Cottin S, Calvez A, Elie JP (1982) Arthroses érosives atloïdo-axoïdiennes. Rev Rhum 49:365–369
39.
go back to reference Miller JDR, Percy JS (1984) Tophaceous gout in the cervical spine. J Rheumatol 11:862–865 Miller JDR, Percy JS (1984) Tophaceous gout in the cervical spine. J Rheumatol 11:862–865
40.
go back to reference Lagier R, MacGee W (1983) Spondylodiscal erosions due to gout: anatomicoradiological study of a case. Ann Rheum Dis 42:350–353 Lagier R, MacGee W (1983) Spondylodiscal erosions due to gout: anatomicoradiological study of a case. Ann Rheum Dis 42:350–353
41.
go back to reference Marsaudon E, Bouchard C, Langand D (1999) Compression radiculaire par un tophus goutteux vertébral: à propos d’un cas et revue de la littérature. Rev Méd Intern 20:253–257 Marsaudon E, Bouchard C, Langand D (1999) Compression radiculaire par un tophus goutteux vertébral: à propos d’un cas et revue de la littérature. Rev Méd Intern 20:253–257
42.
go back to reference Duprez TP, Malghem J, Vande Berg BC, Noel HM, Munting EA, Maldague BE (1996) Gout in the cervical spine: MR pattern mimicking diskovertebral infection. Am J Neuroradiol 17:151–153 Duprez TP, Malghem J, Vande Berg BC, Noel HM, Munting EA, Maldague BE (1996) Gout in the cervical spine: MR pattern mimicking diskovertebral infection. Am J Neuroradiol 17:151–153
43.
go back to reference Van de Perre S, Vanhoenacker FM, Op de Beeck B, Gielen JL, De Schepper AM (2003) Paraspinal cervical calcifications associated with scleroderma. JBR-BTR 86:80–82 Van de Perre S, Vanhoenacker FM, Op de Beeck B, Gielen JL, De Schepper AM (2003) Paraspinal cervical calcifications associated with scleroderma. JBR-BTR 86:80–82
44.
go back to reference Menkes CJ, Kahan A, Feldmann JL, Vinh T (1983) Destructive cervical spondylitis. An unusual initial manifestation of ankylosing spondylitis. Presse Med 12:227–229 Menkes CJ, Kahan A, Feldmann JL, Vinh T (1983) Destructive cervical spondylitis. An unusual initial manifestation of ankylosing spondylitis. Presse Med 12:227–229
Metadata
Title
Cervical spine and crystal-associated diseases: imaging findings
Authors
Antoine Feydy
Frédéric Lioté
Robert Carlier
Alain Chevrot
Jean-Luc Drapé
Publication date
01-02-2006
Publisher
Springer-Verlag
Published in
European Radiology / Issue 2/2006
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-005-2776-z

Other articles of this Issue 2/2006

European Radiology 2/2006 Go to the issue