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Published in: Rheumatology International 11/2009

01-09-2009 | Original Paper

Prognostic indicators related to death in patients with Pneumocystis pneumonia associated with collagen vascular diseases

Authors: Yoko Aoki, Masahiro Iwamoto, Yasuyuki Kamata, Takao Nagashima, Taku Yoshio, Hitoaki Okazaki, Seiji Minota

Published in: Rheumatology International | Issue 11/2009

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Abstract

The objective of this study is to investigate the clinical markers of life-threatening Pneumocystis pneumonia (PCP) in patients with collagen vascular diseases (CVD). The patients who contracted Pneumocystis jeroveccii were retrospectively selected from our medical charts and conditions related to the patients’ death were reviewed. The findings indicated that lower levels of serum albumin and cholinesterase, increased alveolar–arterial oxygen gradient, intratracheal intubation, and necessity to treat in the intensive care unit were significantly related to deaths associated with PCP in CVD. A special attention should be paid to decreased serum albumin and cholinesterase as ominous predictors in PCP occurred in patients with CVD.
Literature
3.
go back to reference Yasuoka A, Tachikawa N, Shimada K et al (1996) (1 → 3) β-d-glucan as a quantitative serological marker for Pneumocystis carinii pneumonia. Clin Diagn Lab Immunol 3:197–199PubMed Yasuoka A, Tachikawa N, Shimada K et al (1996) (1 → 3) β-d-glucan as a quantitative serological marker for Pneumocystis carinii pneumonia. Clin Diagn Lab Immunol 3:197–199PubMed
4.
go back to reference Saito K, Nakayamada S, Nakano K et al (2004) Detection of Pneumocystis carinii by DNA amplication in patients with connective tissue diseases: re-evaluation of clinical features of P. carinii pneumonia in rheumatic diseases. Rheumatology 43:479–485. doi:10.1093/rheumatology/keh071 PubMedCrossRef Saito K, Nakayamada S, Nakano K et al (2004) Detection of Pneumocystis carinii by DNA amplication in patients with connective tissue diseases: re-evaluation of clinical features of P. carinii pneumonia in rheumatic diseases. Rheumatology 43:479–485. doi:10.​1093/​rheumatology/​keh071 PubMedCrossRef
5.
go back to reference Limper AH, Offord KP, Smith TF et al (1989) Pneumocystis carinii pneumonia. Differences in lung parasite number and inflammation in patients with and without AIDS. Am Rev Respir Dis 140:1204–1209PubMed Limper AH, Offord KP, Smith TF et al (1989) Pneumocystis carinii pneumonia. Differences in lung parasite number and inflammation in patients with and without AIDS. Am Rev Respir Dis 140:1204–1209PubMed
6.
go back to reference Ward MM, Donald F (1999) Pneumocystis carinii pneumonia in patients with connective tissue diseases. Arthritis Rheum 42:780–789. doi:10.1002/1529-0131(199904)42:4<780::AID-ANR23>3.0.CO;2-MPubMedCrossRef Ward MM, Donald F (1999) Pneumocystis carinii pneumonia in patients with connective tissue diseases. Arthritis Rheum 42:780–789. doi:10.1002/1529-0131(199904)42:4<780::AID-ANR23>3.0.CO;2-MPubMedCrossRef
7.
go back to reference Godeau B, Coutant-Perronne V, Huong DLT et al (1994) Pneumocystis carinii pneumonia in the course of connective tissue disease: report of 34 cases. J Rheumatol 21:246–251PubMed Godeau B, Coutant-Perronne V, Huong DLT et al (1994) Pneumocystis carinii pneumonia in the course of connective tissue disease: report of 34 cases. J Rheumatol 21:246–251PubMed
10.
go back to reference Iwama A, Yoshida M, Miwa A et al (1993) Improved survival from fungaemia in patients with haematological malignancies: analysis of risk factors for death and usefulness of early antifungal therapy. Eur J Haematol 51:156–160PubMedCrossRef Iwama A, Yoshida M, Miwa A et al (1993) Improved survival from fungaemia in patients with haematological malignancies: analysis of risk factors for death and usefulness of early antifungal therapy. Eur J Haematol 51:156–160PubMedCrossRef
Metadata
Title
Prognostic indicators related to death in patients with Pneumocystis pneumonia associated with collagen vascular diseases
Authors
Yoko Aoki
Masahiro Iwamoto
Yasuyuki Kamata
Takao Nagashima
Taku Yoshio
Hitoaki Okazaki
Seiji Minota
Publication date
01-09-2009
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 11/2009
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-009-0857-z

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