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CardioVascular and Interventional Radiology

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01-11-2019 | Liver Transplantation | Clinical Investigation

Transjugular Liver Biopsy Following Left Lobe or Lateral Segment Transplantation in Pediatric Patients

Authors: Doan-Khac-Viet Tran, Gi-Young Ko, Kyu-Bo Sung, Dong Il Gwon

Published in: CardioVascular and Interventional Radiology | Issue 11/2019

Abstract

Purpose

To evaluate the efficacy and safety of transjugular liver biopsy in pediatric patients with left lobe or lateral segment liver transplant.

Materials and Methods

This was a retrospective study of data from 104 transjugular liver biopsies (57 children) using an 18- or 19-G biopsy needle. Transjugular liver biopsy was selected due to coagulopathy and/or ascites in 56 (54%) procedures. The median patient age, body weight, and interval from liver transplantation were 56 months, 16 kg, and 2 months, respectively. Technical success was defined as adequate liver specimens yield determined by the operator at the time of procedure. Complications, the longest length of obtained liver specimens according to needle type, and adequacy for histological diagnosis were analyzed.

Result

Biopsy using a biopsy needle was successfully achieved in 103 procedures (99%). In one procedure, liver samples were obtained using biopsy forceps following unsuccessful attempts with a biopsy needle. Major complication occurred in one procedure following biopsies using both a biopsy needle and biopsy forceps. The patient received transfusion to manage decreased blood pressure and hemoglobin levels although post-biopsy venography did not show extravasation. The median longest length of liver specimens using 18-G (n = 63) and 19-G (n = 40) needles were 10 mm (range, 5–20) and 10 mm (range, 5–20), respectively (p = 0.704). Liver specimens were adequate for histological diagnosis in all procedures.

Conclusion

Transjugular liver biopsy using a biopsy needle appears to be a safe and effective method to obtain liver specimens for histological diagnosis in pediatric patients with left lobe or lateral segment liver transplant.

Level of Evidence

Level 4, case series.

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Title: Transjugular Liver Biopsy Following Left Lobe or Lateral Segment Transplantation in Pediatric Patients
Authors: Doan-Khac-Viet Tran
Gi-Young Ko
Kyu-Bo Sung
Dong Il Gwon
Publication date: 01-11-2019
Publisher: Springer US
Keywords: Liver Transplantation
Liver Transplantation
Liver Transplantation
Ascites
Liver Transplantation
Liver Transplantation
Phlebography
Published in: CardioVascular and Interventional Radiology / Issue 11/2019
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-019-02301-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Transjugular Liver Biopsy Following Left Lobe or Lateral Segment Transplantation in Pediatric Patients

Abstract

Purpose

Materials and Methods

Result

Conclusion

Level of Evidence

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and Methods

Result

Conclusion

Level of Evidence

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