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CardioVascular and Interventional Radiology

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01-10-2014 | Clinical Investigation

Comparison of CT-Guided Percutaneous Biopsy with and Without Registration of Prior PET/CT Images to Diagnose Mediastinal Tumors

Authors: Koichi Yokoyama, Osamu Ikeda, Koichi Kawanaka, Yutaka Nakasone, Yoshitaka Tamura, Seijiro Inoue, Fumi Sakamoto, Morikatsu Yoshida, Shinya Shiraishi, Yasuyuki Yamashita

Published in: CardioVascular and Interventional Radiology | Issue 5/2014

Abstract

Purpose

To compare computed tomography (CT)-guided percutaneous biopsy with and without registration of prior positron emission tomography (PET)/CT images in the diagnosis of mediastinal tumors.

Methods

We performed clinically indicated percutaneous biopsy in 106 patients with mediastinal tumors in the anterior (n = 61), posterior (n = 21), middle (n = 16), and superior mediastinum (n = 8). The final diagnosis was based on surgical outcomes, or imaging findings and the results of at least 6-month follow-up. The patients underwent CT-guided percutaneous biopsy with (group 1, n = 56) or without (group 2, n = 50) registration of prior PET/CT images obtained no more than 22 days earlier. The registered images were used to plan the procedure and help target the tumors.

Results

CT-guided percutaneous needle biopsy yielded adequate samples in 101 of 106 (95 %) patients (group 1, n = 53; group 2, n = 48); in 95 patients (94 %), the diagnosis was confirmed by specific histological typing (group 1, n = 51; group 2, n = 44). The diagnostic accuracy of CT-guided percutaneous biopsy with and without the registration of prior PET/CT images was not statistically different (group 1, 96 %; group 2, 93 %, p = 0.324).

Conclusion

CT-guided percutaneous biopsy is an easy and safe procedure that can provide a precise diagnosis in the majority of mediastinal tumors. PET/CT-guided biopsy yielded no special diagnostic advantages.

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Title: Comparison of CT-Guided Percutaneous Biopsy with and Without Registration of Prior PET/CT Images to Diagnose Mediastinal Tumors
Authors: Koichi Yokoyama
Osamu Ikeda
Koichi Kawanaka
Yutaka Nakasone
Yoshitaka Tamura
Seijiro Inoue
Fumi Sakamoto
Morikatsu Yoshida
Shinya Shiraishi
Yasuyuki Yamashita
Publication date: 01-10-2014
Publisher: Springer US
Published in: CardioVascular and Interventional Radiology / Issue 5/2014
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-013-0793-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Comparison of CT-Guided Percutaneous Biopsy with and Without Registration of Prior PET/CT Images to Diagnose Mediastinal Tumors

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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