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Published in: World Journal of Surgery 9/2019

Open Access 01-09-2019 | Laryngoscopy

Incidence, Risk Factors, and Natural Outcome of Vocal Fold Paresis in 920 Thyroid Operations with Routine Pre- and Postoperative Laryngoscopic Evaluation

Authors: Maria Heikkinen, Kimmo Mäkinen, Elina Penttilä, Mari Qvarnström, Tatu Kemppainen, Heikki Löppönen, Jussi M. Kärkkäinen

Published in: World Journal of Surgery | Issue 9/2019

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Abstract

Background

The aim of this study was to determine the incidence, risk factors, and spontaneous recovery rate of vocal fold paresis (VFP) with routine laryngoscopy before and after thyroid surgery.

Methods

All consecutive patients undergoing primary or redo thyroid surgery between years 2011–2016 were prospectively registered in an electronic database, and scheduled for pre- and postoperative laryngoscopic vocal fold inspection by otolaryngologists independently of the surgical team.

Results

A total of 920 thyroid operations with 1296 nerves at risk were performed in 866 patients. Pre- and postoperative laryngoscopy was done in 95% and 98%, respectively. Preoperative VFP was detected in 24 (2.8%) patients. New postoperative VFP was found in 53 of 920 operations (5.8%) and in 55 of 1296 nerves at risk (4.2%). After 12 months, 14 had recovered full vocal fold function and eight had near-complete recovery. VFP was permanent after 29 operations (3.2%); two patients were lost to follow-up with uncertain outcome. Of the 1296 nerves at risk, injury was permanent in 30 (2.3%). In multivariate analysis, patients operated for recurrent goiter had nearly nine times higher risk of new VFP (23% rate), whereas patients with malignant histology had three times higher risk of postoperative VFP (up to 22% rate).

Conclusion

VFP continues to be a serious complication of thyroid surgery, especially in operations for redo goiter and thyroid malignancy. The incidence of VFP may be underestimated unless laryngoscopic examinations are performed routinely.
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Metadata
Title
Incidence, Risk Factors, and Natural Outcome of Vocal Fold Paresis in 920 Thyroid Operations with Routine Pre- and Postoperative Laryngoscopic Evaluation
Authors
Maria Heikkinen
Kimmo Mäkinen
Elina Penttilä
Mari Qvarnström
Tatu Kemppainen
Heikki Löppönen
Jussi M. Kärkkäinen
Publication date
01-09-2019
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 9/2019
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-019-05021-y

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