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Published in: World Journal of Surgery 3/2013

01-03-2013

One-Stage Hepatectomy Following Portal Vein Embolization for Colorectal Liver Metastasis

Authors: Suguru Yamashita, Kiyoshi Hasegawa, Michiro Takahashi, Yosuke Inoue, Yoshihiro Sakamoto, Taku Aoki, Yasuhiko Sugawara, Norihiro Kokudo

Published in: World Journal of Surgery | Issue 3/2013

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Abstract

Background

Although portal vein embolization (PVE) has been applied for surgical resection of colorectal liver metastases (CLM), the clinical usefulness of liver surgery following PVE for CLM remains unknown.

Methods

A total of 115 patients were evaluated retrospectively. Among them, 49 underwent one-stage hepatectomy following PVE (PVE group). The remaining 66 patients underwent at least hemihepatectomy without PVE (non-PVE group). This analysis compared the short- and long-term outcomes between the PVE and non-PVE groups.

Results

There were no deaths in either group. Using the Clavien–Dindo classification, the rates of postoperative morbidity ≥ grade 1 were 34.7 % in the PVE group and 25.0 % in the non-PVE group (p = 0.26). The 3-year overall survival rates were 54.6 and 64.5 % in the PVE and non-PVE groups, respectively (p = 0.89). The multivariate analysis the variable performance/nonperformance of PVE was not detected as an independent predictor of poor survival.

Conclusions

Our one-stage hepatectomy policy of using PVE provides acceptable morbidity and favorable long-term outcomes.
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Metadata
Title
One-Stage Hepatectomy Following Portal Vein Embolization for Colorectal Liver Metastasis
Authors
Suguru Yamashita
Kiyoshi Hasegawa
Michiro Takahashi
Yosuke Inoue
Yoshihiro Sakamoto
Taku Aoki
Yasuhiko Sugawara
Norihiro Kokudo
Publication date
01-03-2013
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 3/2013
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-012-1861-0

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