Skip to main content
Top
Published in: World Journal of Surgery 7/2012

01-07-2012

Subcuticular Absorbable Suture with Subcutaneous Drainage System Prevents Incisional SSI after Hepatectomy for Hepatocellular Carcinoma

Authors: Eiji Tsujita, Yo-ichi Yamashita, Kazuki Takeishi, Ayumi Matsuyama, Shin-ichi Tsutsui, Hiroyuki Matsuda, Akinobu Taketomi, Ken Shirabe, Teruyoshi Ishida, Yoshihiko Maehara

Published in: World Journal of Surgery | Issue 7/2012

Login to get access

Abstract

Background

The effectiveness of subcuticular absorbable suture with subcutaneous drainage to decrease the risk of postoperative incisional surgical site infection (SSI) in hepatocellular carcinoma (HCC) patients was evaluated.

Methods

A total of 149 patients with HCC who underwent hepatectomy (Hx) were retrospectively investigated. Patients were divided into two groups: the patients with subcuticular suture combined with subcutaneous drainage (the drainage group; 61 patients) and the patients with nylon suture without subcutaneous drainage (the nylon group; 88 patients). After the operations, the complication rate of postoperative incisional SSI was analyzed and compared between the two groups.

Results

In the drainage group the rate of incisional SSI was significantly lower compared to the nylon group: 14–3 % (p = 0.033), respectively. Patients with incisional SSI needed significantly longer postoperative hospital care than the patients without incisional SSI: 28 versus 15 days (p < 0.005). Multivariate analysis revealed that subcuticular absorbable suture with subcutaneous drainage significantly reduced the occurrence of incisional SSI (odds ratio; 0.15; p = 0.034).

Conclusions

We have demonstrated that the subcuticular suture with subcutaneous drainage is effective in preventing incisional SSI in patients undergoing Hx for HCC.
Literature
1.
go back to reference Taketomi A, Kitagawa D, Itoh S et al (2007) Trends in morbidity and mortality after hepatic resection for hepatocellular carcinoma: an institute’s experience with 625 patients. J Am Coll Surg 204:580–587PubMedCrossRef Taketomi A, Kitagawa D, Itoh S et al (2007) Trends in morbidity and mortality after hepatic resection for hepatocellular carcinoma: an institute’s experience with 625 patients. J Am Coll Surg 204:580–587PubMedCrossRef
2.
go back to reference Belghiti J, Hiramatsu K, Benoist S et al (2000) Seven hundred forty-seven hepatectomies in the 1990s: an update to evaluate the actual risk of liver resection. J Am Coll Surg 191:38–46PubMedCrossRef Belghiti J, Hiramatsu K, Benoist S et al (2000) Seven hundred forty-seven hepatectomies in the 1990s: an update to evaluate the actual risk of liver resection. J Am Coll Surg 191:38–46PubMedCrossRef
3.
go back to reference McGowan JE Jr (1991) Cost and benefit of perioperative antimicrobial prophylaxis: methods for economic analysis. Rev Infect Dis 13:S879–S889PubMedCrossRef McGowan JE Jr (1991) Cost and benefit of perioperative antimicrobial prophylaxis: methods for economic analysis. Rev Infect Dis 13:S879–S889PubMedCrossRef
4.
go back to reference Taylor GD, Kirkland TA, McKenzie MM et al (1995) The effect of surgical wound infection on postoperative hospital stay. Can J Surg 38:149–153PubMed Taylor GD, Kirkland TA, McKenzie MM et al (1995) The effect of surgical wound infection on postoperative hospital stay. Can J Surg 38:149–153PubMed
5.
go back to reference Iñigo JJ, Bermejo B, Oronoz B et al (2006) Surgical site infection in general surgery: 5-year analysis and assessment of the national nosocomial infection surveillance (NNIS) index. Cir Esp 79:224–230PubMedCrossRef Iñigo JJ, Bermejo B, Oronoz B et al (2006) Surgical site infection in general surgery: 5-year analysis and assessment of the national nosocomial infection surveillance (NNIS) index. Cir Esp 79:224–230PubMedCrossRef
6.
go back to reference Moy RL, Lee A, Zalka A (1991) Commonly used suture materials in skin surgery. Am Fam Physician 44:2123–2128PubMed Moy RL, Lee A, Zalka A (1991) Commonly used suture materials in skin surgery. Am Fam Physician 44:2123–2128PubMed
7.
go back to reference Higson RH, Kettlewell MG (1978) Parietal wound drainage in abdominal surgery. Br J Surg 65:326–329PubMedCrossRef Higson RH, Kettlewell MG (1978) Parietal wound drainage in abdominal surgery. Br J Surg 65:326–329PubMedCrossRef
8.
go back to reference Gallup DC, Gallup DG, Nolan TE et al (1996) Use of a subcutaneous closed drainage system and antibiotics in obese gynecologic patients. Am J Obstet Gynecol 175:358–361PubMedCrossRef Gallup DC, Gallup DG, Nolan TE et al (1996) Use of a subcutaneous closed drainage system and antibiotics in obese gynecologic patients. Am J Obstet Gynecol 175:358–361PubMedCrossRef
9.
go back to reference Allaire AD, Fisch J, McMahon MJ (2000) Subcutaneous drain versus suture in obese women undergoing cesarean delivery. A prospective, randomized trial. J Reprod Med 45:327–331PubMed Allaire AD, Fisch J, McMahon MJ (2000) Subcutaneous drain versus suture in obese women undergoing cesarean delivery. A prospective, randomized trial. J Reprod Med 45:327–331PubMed
10.
go back to reference Inotsume-Kojima Y, Uchida T, Abe M et al (2011) A combination of subcuticular sutures and a drain for skin closure reduces wound complications in obese women undergoing surgery using vertical incisions. J Hosp Infect 77:162–165PubMedCrossRef Inotsume-Kojima Y, Uchida T, Abe M et al (2011) A combination of subcuticular sutures and a drain for skin closure reduces wound complications in obese women undergoing surgery using vertical incisions. J Hosp Infect 77:162–165PubMedCrossRef
11.
go back to reference Fujii T, Tabe Y, Yajima R et al. Effects of subcutaneous drain for the prevention of incisional SSI in high-risk patients undergoing colorectal surgery. Int J Colorectal Dis 26: 1551-1555 (in press) Fujii T, Tabe Y, Yajima R et al. Effects of subcutaneous drain for the prevention of incisional SSI in high-risk patients undergoing colorectal surgery. Int J Colorectal Dis 26: 1551-1555 (in press)
12.
go back to reference Yamashita Y, Taketomi A, Itoh S et al (2007) Longterm favorable results of limited hepatic resections for patients with hepatocellular carcinoma: 20 years of experience. J Am Coll Surg 205:19–26PubMedCrossRef Yamashita Y, Taketomi A, Itoh S et al (2007) Longterm favorable results of limited hepatic resections for patients with hepatocellular carcinoma: 20 years of experience. J Am Coll Surg 205:19–26PubMedCrossRef
13.
go back to reference Pugh RN, Murray-Lyon IM, Dawson JL et al (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60:646–649PubMedCrossRef Pugh RN, Murray-Lyon IM, Dawson JL et al (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60:646–649PubMedCrossRef
14.
go back to reference Liver Cancer Study Group of Japan (2008) The general rules for the clinical and pathological study of primary liver cancer. Tokyo, Kanehara & Co., Ltd Liver Cancer Study Group of Japan (2008) The general rules for the clinical and pathological study of primary liver cancer. Tokyo, Kanehara & Co., Ltd
15.
go back to reference Fiennes AG (1985) Interrupted subcuticular polyglactin sutures for abdominal wounds. Ann R Coll Surg Engl 67:121PubMed Fiennes AG (1985) Interrupted subcuticular polyglactin sutures for abdominal wounds. Ann R Coll Surg Engl 67:121PubMed
16.
go back to reference Yamashita Y, Hamatsu T, Rikimaru T et al (2001) Bile leakage after hepatic resection. Ann Surg 233:45–50PubMedCrossRef Yamashita Y, Hamatsu T, Rikimaru T et al (2001) Bile leakage after hepatic resection. Ann Surg 233:45–50PubMedCrossRef
17.
go back to reference Okabayashi T, Nishimori I, Yamashita K et al (2009) Risk factors and predictors for surgical site infection after hepatic resection. J Hosp Infect 73:47–53PubMedCrossRef Okabayashi T, Nishimori I, Yamashita K et al (2009) Risk factors and predictors for surgical site infection after hepatic resection. J Hosp Infect 73:47–53PubMedCrossRef
18.
go back to reference Horan TC, Gaynes RP, Martone WJ et al (1992) CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13:606–608PubMedCrossRef Horan TC, Gaynes RP, Martone WJ et al (1992) CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13:606–608PubMedCrossRef
20.
go back to reference Parell GJ, Becker GD (2003) Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds. Arch Facial Plast Surg 5:488–490PubMedCrossRef Parell GJ, Becker GD (2003) Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds. Arch Facial Plast Surg 5:488–490PubMedCrossRef
22.
go back to reference Togo S, Kubota T, Takahashi T et al (2008) Usefulness of absorbable sutures in preventing surgical site infection in hepatectomy. J Gastrointest Surg 12:1041–1046PubMedCrossRef Togo S, Kubota T, Takahashi T et al (2008) Usefulness of absorbable sutures in preventing surgical site infection in hepatectomy. J Gastrointest Surg 12:1041–1046PubMedCrossRef
23.
go back to reference Kusano T, Sasaki A, Kai S et al (2009) Predictors and prognostic significance of operative complications in patients with hepatocellular carcinoma who underwent hepatic resection. Eur J Surg Oncol 35:1179–1185PubMedCrossRef Kusano T, Sasaki A, Kai S et al (2009) Predictors and prognostic significance of operative complications in patients with hepatocellular carcinoma who underwent hepatic resection. Eur J Surg Oncol 35:1179–1185PubMedCrossRef
24.
go back to reference Sadamori H, Yagi T, Matsuda H et al (2010) Risk factors for major morbidity after hepatectomy for hepatocellular carcinoma in 293 recent cases. J Hepatobiliary Pancreat Sci 17:709–718PubMedCrossRef Sadamori H, Yagi T, Matsuda H et al (2010) Risk factors for major morbidity after hepatectomy for hepatocellular carcinoma in 293 recent cases. J Hepatobiliary Pancreat Sci 17:709–718PubMedCrossRef
25.
go back to reference Liu CL, Fan ST, Lo CM et al (2004) Abdominal drainage after hepatic resection is contraindicated in patients with chronic liver diseases. Ann Surg 239:194–201PubMedCrossRef Liu CL, Fan ST, Lo CM et al (2004) Abdominal drainage after hepatic resection is contraindicated in patients with chronic liver diseases. Ann Surg 239:194–201PubMedCrossRef
26.
go back to reference Harimoto N, Shirabe K, Abe T et al (2011) Prospective randomized controlled trial investigating the type of sutures used during hepatectomy. World J Gastroenterol 14:2338–2342CrossRef Harimoto N, Shirabe K, Abe T et al (2011) Prospective randomized controlled trial investigating the type of sutures used during hepatectomy. World J Gastroenterol 14:2338–2342CrossRef
27.
go back to reference Pessaux P, Msika S, Atalla D, The French Association for Surgical Research et al (2003) Risk factors for postoperative infectious complications in noncolorectal abdominal surgery: a multivariate analysis based on a prospective multicenter study of 4718 patients. Arch Surg 138:314–324PubMedCrossRef Pessaux P, Msika S, Atalla D, The French Association for Surgical Research et al (2003) Risk factors for postoperative infectious complications in noncolorectal abdominal surgery: a multivariate analysis based on a prospective multicenter study of 4718 patients. Arch Surg 138:314–324PubMedCrossRef
28.
go back to reference Rimola A (1987) Infections au cours des maladies hépatiques. In Hépatologie Clinique. Paris, Flammarion Médecine-Sciences p 1272–1284 Rimola A (1987) Infections au cours des maladies hépatiques. In Hépatologie Clinique. Paris, Flammarion Médecine-Sciences p 1272–1284
29.
go back to reference Hirsch S, Bunout D, De la Maza MP et al (1993) Controlled trial on nutrition supplementation in outpatients with symptomatic alcoholic cirrhosis. JPEN 17:119–124CrossRef Hirsch S, Bunout D, De la Maza MP et al (1993) Controlled trial on nutrition supplementation in outpatients with symptomatic alcoholic cirrhosis. JPEN 17:119–124CrossRef
30.
go back to reference Hirsch S, de la Maza MP, Gattás V et al (1999) Nutritional support in alcoholic cirrhotic patients improves host defenses. J Am Coll Nutr 18:434–441PubMed Hirsch S, de la Maza MP, Gattás V et al (1999) Nutritional support in alcoholic cirrhotic patients improves host defenses. J Am Coll Nutr 18:434–441PubMed
31.
go back to reference Sorg H, Schulz T, Krueger C et al (2009) Consequences of surgical stress on the kinetics of skin wound healing: partial hepatectomy delays and functionally alters dermal repair. Wound Repair Regen 17:367–377PubMedCrossRef Sorg H, Schulz T, Krueger C et al (2009) Consequences of surgical stress on the kinetics of skin wound healing: partial hepatectomy delays and functionally alters dermal repair. Wound Repair Regen 17:367–377PubMedCrossRef
32.
go back to reference Zografos GC, Iftikhar SY, Harrison J et al (1990) Evaluation of blood flow in human rectal tumours using a laser Doppler flowmeter. Eur J Surg Oncol 16:497–499PubMed Zografos GC, Iftikhar SY, Harrison J et al (1990) Evaluation of blood flow in human rectal tumours using a laser Doppler flowmeter. Eur J Surg Oncol 16:497–499PubMed
33.
go back to reference Ray JA, Doddi N, Regula D et al (1981) (Polydioxanone (PDS), a novel monofilament synthetic absorbable suture. Surg Gynecol Obstet 153:497–507PubMed Ray JA, Doddi N, Regula D et al (1981) (Polydioxanone (PDS), a novel monofilament synthetic absorbable suture. Surg Gynecol Obstet 153:497–507PubMed
34.
go back to reference Ramsey PS, White AM, Guinn DA et al (2005) Subcutaneous tissue reapproximation, alone or in combination with drain, in obese women undergoing cesarean delivery. Obstet Gynecol 105:967–973PubMedCrossRef Ramsey PS, White AM, Guinn DA et al (2005) Subcutaneous tissue reapproximation, alone or in combination with drain, in obese women undergoing cesarean delivery. Obstet Gynecol 105:967–973PubMedCrossRef
35.
go back to reference Cardosi RJ, Drake J, Holmes S et al (2006) Subcutaneous management of vertical incisions with 3 or more centimeters of subcutaneous fat. Am J Obstet Gynecol 195:607–614PubMedCrossRef Cardosi RJ, Drake J, Holmes S et al (2006) Subcutaneous management of vertical incisions with 3 or more centimeters of subcutaneous fat. Am J Obstet Gynecol 195:607–614PubMedCrossRef
36.
go back to reference Johnson A, Young D, Reilly J (2006) Caesarean section surgical site infection surveillance. J Hosp Infect 64:30–35PubMedCrossRef Johnson A, Young D, Reilly J (2006) Caesarean section surgical site infection surveillance. J Hosp Infect 64:30–35PubMedCrossRef
Metadata
Title
Subcuticular Absorbable Suture with Subcutaneous Drainage System Prevents Incisional SSI after Hepatectomy for Hepatocellular Carcinoma
Authors
Eiji Tsujita
Yo-ichi Yamashita
Kazuki Takeishi
Ayumi Matsuyama
Shin-ichi Tsutsui
Hiroyuki Matsuda
Akinobu Taketomi
Ken Shirabe
Teruyoshi Ishida
Yoshihiko Maehara
Publication date
01-07-2012
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 7/2012
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-012-1524-1

Other articles of this Issue 7/2012

World Journal of Surgery 7/2012 Go to the issue