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Published in: World Journal of Surgery 8/2011

01-08-2011

Predictive Factors for Bile Leakage After Hepatectomy: Analysis of 505 Consecutive Patients

Authors: Ryuji Yoshioka, Akio Saiura, Rintaro Koga, Makoto Seki, Yoji Kishi, Junji Yamamoto

Published in: World Journal of Surgery | Issue 8/2011

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Abstract

Background

Bile leakage is the most common complication after hepatectomy and its incidence is not declining. The aim of the present study was to identify predictive factors for bile leakage.

Methods

Clinical data from 505 consecutive patients who underwent hepatectomy without extrahepatic bile duct resection in our department between January 2006 and December 2009 were reviewed retrospectively.

Results

The incidence of bile leakage was found to be 6.7%. Multivariate analysis identified three independent factors that were significantly correlated with the occurrence of bile leakage: (1) repeat hepatectomy (P = 0.002; odds ratio [OR] 3.439; 95% confidence interval [CI] 1.552–7.618), (2) a cut surface area ≥57.5 cm2 (P = 0.004; OR 5.296; 95% CI 1.721–16.302), and (3) intraoperative blood loss ≥775 ml (P = 0.01; OR 2.808; 95% CI 1.280–6.160).

Conclusion

More meticulous management is needed to prevent bile leakage in high-risk patients.
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Metadata
Title
Predictive Factors for Bile Leakage After Hepatectomy: Analysis of 505 Consecutive Patients
Authors
Ryuji Yoshioka
Akio Saiura
Rintaro Koga
Makoto Seki
Yoji Kishi
Junji Yamamoto
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 8/2011
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-011-1114-7

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