Published in:
01-08-2011
Predictive Factors for Bile Leakage After Hepatectomy: Analysis of 505 Consecutive Patients
Authors:
Ryuji Yoshioka, Akio Saiura, Rintaro Koga, Makoto Seki, Yoji Kishi, Junji Yamamoto
Published in:
World Journal of Surgery
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Issue 8/2011
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Abstract
Background
Bile leakage is the most common complication after hepatectomy and its incidence is not declining. The aim of the present study was to identify predictive factors for bile leakage.
Methods
Clinical data from 505 consecutive patients who underwent hepatectomy without extrahepatic bile duct resection in our department between January 2006 and December 2009 were reviewed retrospectively.
Results
The incidence of bile leakage was found to be 6.7%. Multivariate analysis identified three independent factors that were significantly correlated with the occurrence of bile leakage: (1) repeat hepatectomy (P = 0.002; odds ratio [OR] 3.439; 95% confidence interval [CI] 1.552–7.618), (2) a cut surface area ≥57.5 cm2 (P = 0.004; OR 5.296; 95% CI 1.721–16.302), and (3) intraoperative blood loss ≥775 ml (P = 0.01; OR 2.808; 95% CI 1.280–6.160).
Conclusion
More meticulous management is needed to prevent bile leakage in high-risk patients.