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World Journal of Surgery

Published in:

01-12-2010

Gastric Tube Reconstruction by Laparoscopy-Assisted Surgery Attenuates Postoperative Systemic Inflammatory Response after Esophagectomy for Esophageal Cancer

Authors: Hironori Tsujimoto, Satoshi Ono, Hidekazu Sugasawa, Takashi Ichikura, Junji Yamamoto, Kazuo Hase

Published in: World Journal of Surgery | Issue 12/2010

Abstract

Background

Conventional open procedures have been supplanted in part by less invasive approaches, such as laparoscopic surgery developed for treating gastrointestinal malignancies. However, it is unclear whether laparoscopy-assisted gastric tube reconstruction (LAGT) can attenuate the postoperative systemic inflammatory response after esophagectomy for esophageal cancer.

Methods

We investigated the postoperative clinical course of the systemic inflammatory response syndrome (SIRS) in patients who underwent an esophagectomy for esophageal cancer by LAGT (LAGT group) and gastric tube reconstruction by conventional open surgery (Open group).

Results

Compared with the Open group, the LAGT group had a significantly shorter operative time (539.6 min vs. 639.8 min), shorter duration of postoperative mechanical ventilation (1.1 days vs. 2.8 days), and shorter length of stay in the intensive care unit (2.1 days vs. 4.4 days). The LAGT group also had a significantly shorter SIRS duration (1.4 days vs. 2.7 days), a significantly lower incidence of SIRS, and a smaller number of positive SIRS criteria. Throughout the investigation period, the postoperative white blood cell count was lower in the LAGT group than in the Open group. Additionally, in the LAGT group, the heart rate was lower on each postoperative day (POD), and the respiratory rate was significantly lower on postoperative days (PODs) 1 and 4. There was no difference in postoperative oxygenation, morbidity, and mortality between the groups. The C-reactive protein level on PODs 3 and 4 was significantly lower in the LAGT group than in the Open group.

Conclusions

Laparoscopy-assisted gastric tube reconstruction significantly attenuates postoperative SIRS, and it is therefore a potentially less invasive surgical procedure.

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Title: Gastric Tube Reconstruction by Laparoscopy-Assisted Surgery Attenuates Postoperative Systemic Inflammatory Response after Esophagectomy for Esophageal Cancer
Authors: Hironori Tsujimoto
Satoshi Ono
Hidekazu Sugasawa
Takashi Ichikura
Junji Yamamoto
Kazuo Hase
Publication date: 01-12-2010
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 12/2010
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-010-0757-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Gastric Tube Reconstruction by Laparoscopy-Assisted Surgery Attenuates Postoperative Systemic Inflammatory Response after Esophagectomy for Esophageal Cancer

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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