Skip to main content
Top
Published in: World Journal of Surgery 12/2009

01-12-2009

“Paraduodenal” Pancreatitis: Results of Surgery on 58 Consecutives Patients from a Single Institution

Authors: L. Casetti, C. Bassi, R. Salvia, G. Butturini, R. Graziani, M. Falconi, L. Frulloni, S. Crippa, G. Zamboni, P. Pederzoli

Published in: World Journal of Surgery | Issue 12/2009

Login to get access

Abstract

Background

Cystic dystrophy of heterotopic pancreas, groove pancreatitis, pancreatic hamartoma of the duodenum, paraduodenal wall cyst, and myoadenomatosis are all terms grouped together, from a pathological viewpoint, as definitions of paraduodenal pancreatitis (PP). The objective of the present study was to investigate the clinical characteristics, therapeutic strategies, and results in 58 patients undergoing pancreatic resection for PP.

Methods

From January 1990 to December 2006 data were prospectively collected on 58 patients who were diagnosed with PP who then underwent pancreaticoduodenectomy.

Results

In this patient cohort the median age was 44.7 years; only 4 patients were women, and only 3 had non-drinker and/or non smoker habits. The overall morbidity was 18.9%, and the median hospitalization was 11 days. There were no postoperative deaths. In a median follow-up of 96.3 months, all patients noted a decrease in the pain associated with PP; 35 patients (76%) had complete disappearance of pain, whereas occasional relapsing pain occurred in the remaining 11 (24%).

Conclusions

Patients with PP have clinical characteristics similar to those of chronic pancreatitis. The diagnostic imaging modalities of choice are ultrasonographic endoscopy and magnetic resonance cholangiopancreaticography. Based on our surgical experience, pancreaticoduodenectomy seems to be a reasonable choice of treatment in patients with PP.
Literature
1.
go back to reference Adsay NV, Zamboni G (2004) Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying “cystic dystrophy of heterotopic pancreas”, “para-duodenal wall cyst”, and “groove pancreatitis”. Semin Diagn Pathol 21:247–254CrossRefPubMed Adsay NV, Zamboni G (2004) Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying “cystic dystrophy of heterotopic pancreas”, “para-duodenal wall cyst”, and “groove pancreatitis”. Semin Diagn Pathol 21:247–254CrossRefPubMed
2.
go back to reference Potet F, Duclert N (1970) Cystic dystrophy on aberrant pancreas of the duodenal wall. Arch Fr Mal App Dig 59:223–238PubMed Potet F, Duclert N (1970) Cystic dystrophy on aberrant pancreas of the duodenal wall. Arch Fr Mal App Dig 59:223–238PubMed
3.
go back to reference Flejou JF, Potet F, Molas G et al (1993) Cystic dystrophy of the gastric and duodenal wall developing in heterotopic pancreas: an unrecognised entity. Gut 34:343–347CrossRefPubMed Flejou JF, Potet F, Molas G et al (1993) Cystic dystrophy of the gastric and duodenal wall developing in heterotopic pancreas: an unrecognised entity. Gut 34:343–347CrossRefPubMed
4.
go back to reference Visset J, Jais F, Le Bodic MF et al (1992) Cystic dystrophy of aberrant pancreatic tissue in the duodenal wall. Diagnostic and therapeutic problems. Chirurgie 118:634–636PubMed Visset J, Jais F, Le Bodic MF et al (1992) Cystic dystrophy of aberrant pancreatic tissue in the duodenal wall. Diagnostic and therapeutic problems. Chirurgie 118:634–636PubMed
5.
go back to reference Hebrero J, Diego Estevez M, Martinez Arrieta F et al (1980) Cystic dystrophy in pancreatic heterotopia of the duodenal wall. Rev Esp Enferm Apar Dig 57:51–56PubMed Hebrero J, Diego Estevez M, Martinez Arrieta F et al (1980) Cystic dystrophy in pancreatic heterotopia of the duodenal wall. Rev Esp Enferm Apar Dig 57:51–56PubMed
6.
go back to reference Vullierme MP, Vilgrain V, Flejou JF et al (2000) Cystic dystrophy of the duodenal wall in the heterotopic pancreas: radiopathological correlations. J Comput Assist Tomogr 24:635–643CrossRefPubMed Vullierme MP, Vilgrain V, Flejou JF et al (2000) Cystic dystrophy of the duodenal wall in the heterotopic pancreas: radiopathological correlations. J Comput Assist Tomogr 24:635–643CrossRefPubMed
7.
go back to reference Chatelain D, Vibert E, Yzet T et al (2005) Groove pancreatitis and pancreatic heterotopia in the minor duodenal papilla. Pancreas 30:e92–e95CrossRefPubMed Chatelain D, Vibert E, Yzet T et al (2005) Groove pancreatitis and pancreatic heterotopia in the minor duodenal papilla. Pancreas 30:e92–e95CrossRefPubMed
8.
go back to reference Becker V, Mischke U (1991) Groove pancreatitis. Int J Pancreatol 10:173–182PubMed Becker V, Mischke U (1991) Groove pancreatitis. Int J Pancreatol 10:173–182PubMed
9.
go back to reference Scapa E, Broide E, Halevy A et al (1994) Groove pancreatitis and adenocarcinoma of the pancreatic head. Harefuah 127:161–162, 215 Scapa E, Broide E, Halevy A et al (1994) Groove pancreatitis and adenocarcinoma of the pancreatic head. Harefuah 127:161–162, 215
10.
go back to reference Fujita N, Shirai Y, Tsukada K et al (1997) Groove pancreatitis with recurrent duodenal obstruction. Report of a case successfully treated with pylorus-preserving pancreaticoduodenectomy. Int J Pancreatol 21:185–188PubMed Fujita N, Shirai Y, Tsukada K et al (1997) Groove pancreatitis with recurrent duodenal obstruction. Report of a case successfully treated with pylorus-preserving pancreaticoduodenectomy. Int J Pancreatol 21:185–188PubMed
11.
go back to reference Wu SS, Vargas HI, French SW (1998) Pancreatic hamartoma with Langerhans cell histiocytosis in a draining lymph node. Histopathology 33:485–487CrossRefPubMed Wu SS, Vargas HI, French SW (1998) Pancreatic hamartoma with Langerhans cell histiocytosis in a draining lymph node. Histopathology 33:485–487CrossRefPubMed
12.
go back to reference McFaul CD, Vitone LJ, Campbell F et al (2004) Pancreatic hamartoma. Pancreatology 4:533–537; discussion 537–538CrossRefPubMed McFaul CD, Vitone LJ, Campbell F et al (2004) Pancreatic hamartoma. Pancreatology 4:533–537; discussion 537–538CrossRefPubMed
13.
go back to reference Noltenius H, Colmant HJ (1977) Excessive hyperplasia of the exocrine pancreatic tissue and Wernicke’s encephalopathy (author’s transl). Med Klin 72:2155–2158PubMed Noltenius H, Colmant HJ (1977) Excessive hyperplasia of the exocrine pancreatic tissue and Wernicke’s encephalopathy (author’s transl). Med Klin 72:2155–2158PubMed
14.
go back to reference Izbicki JR, Knoefel WT, Muller-Hocker J et al (1994) Pancreatic hamartoma: a benign tumor of the pancreas. Am J Gastroenterol 89:1261–1262PubMed Izbicki JR, Knoefel WT, Muller-Hocker J et al (1994) Pancreatic hamartoma: a benign tumor of the pancreas. Am J Gastroenterol 89:1261–1262PubMed
15.
go back to reference Stolte M, Zink W, Schaffner O (1983) Duodenal wall cysts and diseases of the pancreas. Leber Magen Darm 13:140–149PubMed Stolte M, Zink W, Schaffner O (1983) Duodenal wall cysts and diseases of the pancreas. Leber Magen Darm 13:140–149PubMed
16.
go back to reference Holstege A, Barner S, Brambs HJ et al (1985) Relapsing pancreatitis associated with duodenal wall cysts. Diagnostic approach and treatment. Gastroenterology 88:814–819PubMed Holstege A, Barner S, Brambs HJ et al (1985) Relapsing pancreatitis associated with duodenal wall cysts. Diagnostic approach and treatment. Gastroenterology 88:814–819PubMed
17.
go back to reference Seitz K, Rettenmaier G, Stolte M (1985) Groove pancreatitis—its pathological anatomy and sonographic findings. Ultraschall Med 6:131–133CrossRefPubMed Seitz K, Rettenmaier G, Stolte M (1985) Groove pancreatitis—its pathological anatomy and sonographic findings. Ultraschall Med 6:131–133CrossRefPubMed
18.
go back to reference Suda K, Takase M, Shiono S et al (2002) Duodenal wall cysts may be derived from a ductal component of ectopic pancreatic tissue. Histopathology 41:351–356CrossRefPubMed Suda K, Takase M, Shiono S et al (2002) Duodenal wall cysts may be derived from a ductal component of ectopic pancreatic tissue. Histopathology 41:351–356CrossRefPubMed
19.
go back to reference Bill K, Belber JP, Carson JW (1982) Adenomyoma (pancreatic heterotopia) of the duodenum producing common bile duct obstruction. Gastrointest Endosc 28:182–184CrossRefPubMed Bill K, Belber JP, Carson JW (1982) Adenomyoma (pancreatic heterotopia) of the duodenum producing common bile duct obstruction. Gastrointest Endosc 28:182–184CrossRefPubMed
20.
go back to reference Aoun N, Zafatayeff S, Smayra T et al (2005) Adenomyoma of the ampullary region: imaging findings in four patients. Abdom Imaging 30:86–89CrossRefPubMed Aoun N, Zafatayeff S, Smayra T et al (2005) Adenomyoma of the ampullary region: imaging findings in four patients. Abdom Imaging 30:86–89CrossRefPubMed
21.
go back to reference Parc R, Soprani A, Louvel A (1977) Heterotopic cystic pancreas of the duodenal wall without associated chronic pancreatitis (author’s transl). J Chir (Paris) 114:185–192 Parc R, Soprani A, Louvel A (1977) Heterotopic cystic pancreas of the duodenal wall without associated chronic pancreatitis (author’s transl). J Chir (Paris) 114:185–192
22.
go back to reference Ozeki Y, Onitsuka A, Hayashi M et al (1991) Idiopathic duodenal obstruction resembling pure groove pancreatitis: a case report. Nippon Shokakibyo Gakkai Zasshi 88:1140–1144PubMed Ozeki Y, Onitsuka A, Hayashi M et al (1991) Idiopathic duodenal obstruction resembling pure groove pancreatitis: a case report. Nippon Shokakibyo Gakkai Zasshi 88:1140–1144PubMed
23.
go back to reference Shudo R, Obara T, Tanno S et al (1998) Segmental groove pancreatitis accompanied by protein plugs in Santorini’s duct. J Gastroenterol 33:289–294CrossRefPubMed Shudo R, Obara T, Tanno S et al (1998) Segmental groove pancreatitis accompanied by protein plugs in Santorini’s duct. J Gastroenterol 33:289–294CrossRefPubMed
24.
go back to reference Prandi D, Maillard JN, Potet F (1972) Surgical treatment of cystic dystrophy on aberrant pancreas of the duodenal wall (apropos of 3 cases). Arch Fr Mal App Dig 61:193–198PubMed Prandi D, Maillard JN, Potet F (1972) Surgical treatment of cystic dystrophy on aberrant pancreas of the duodenal wall (apropos of 3 cases). Arch Fr Mal App Dig 61:193–198PubMed
25.
26.
go back to reference Falconi M, Valerio A, Caldiron E et al (2000) Changes in pancreatic resection for chronic pancreatitis over 28 years in a single institution. Br J Surg 87:428–433CrossRefPubMed Falconi M, Valerio A, Caldiron E et al (2000) Changes in pancreatic resection for chronic pancreatitis over 28 years in a single institution. Br J Surg 87:428–433CrossRefPubMed
27.
go back to reference Beger HG, Schlosser W, Friess HM et al (1999) Duodenum-preserving head resection in chronic pancreatitis changes the natural course of the disease: a single-center 26-year experience. Ann Surg 230:512–519; discussion 519–523CrossRefPubMed Beger HG, Schlosser W, Friess HM et al (1999) Duodenum-preserving head resection in chronic pancreatitis changes the natural course of the disease: a single-center 26-year experience. Ann Surg 230:512–519; discussion 519–523CrossRefPubMed
28.
go back to reference Tison C, Leborgne J (2001) Cystic dystrophy of heterotopic duodenal pancreas. J Chir (Paris) 138:205–214 Tison C, Leborgne J (2001) Cystic dystrophy of heterotopic duodenal pancreas. J Chir (Paris) 138:205–214
29.
go back to reference Marmorale A, Tercier S, Peroux JL et al (2003) Cystic dystrophy in heterotopic pancreas of the second part of the duodenum. One case of conservative surgical procedure. Ann Chir 128:180–184CrossRefPubMed Marmorale A, Tercier S, Peroux JL et al (2003) Cystic dystrophy in heterotopic pancreas of the second part of the duodenum. One case of conservative surgical procedure. Ann Chir 128:180–184CrossRefPubMed
30.
go back to reference Glaser M, Roskar Z, Skalicky M et al (2002) Cystic dystrophy of the duodenal wall in a heterotopic pancreas. Wien Klin Wochenschr 114:1013–1016PubMed Glaser M, Roskar Z, Skalicky M et al (2002) Cystic dystrophy of the duodenal wall in a heterotopic pancreas. Wien Klin Wochenschr 114:1013–1016PubMed
31.
go back to reference Bittar I, Cohen Solal JL et al (2000) Cystic dystrophy of an aberrant pancreas. Surgery after failure of medical therapy. Presse Med 29:1118–1120PubMed Bittar I, Cohen Solal JL et al (2000) Cystic dystrophy of an aberrant pancreas. Surgery after failure of medical therapy. Presse Med 29:1118–1120PubMed
32.
go back to reference Desrame J, Minvielle F, Thiolet C et al (2000) Cystic dystrophia of the duodenal wall with aberrant pancreas. Value of magnetic resonance imaging for diagnosis. Presse Med 29:1759–1761PubMed Desrame J, Minvielle F, Thiolet C et al (2000) Cystic dystrophia of the duodenal wall with aberrant pancreas. Value of magnetic resonance imaging for diagnosis. Presse Med 29:1759–1761PubMed
33.
go back to reference Rey P, Carrere C, Tissier S et al (2003) Groove pancreatitis. Diagnostic impact of dynamic radiology. Presse Med 32:1705–1706PubMed Rey P, Carrere C, Tissier S et al (2003) Groove pancreatitis. Diagnostic impact of dynamic radiology. Presse Med 32:1705–1706PubMed
34.
go back to reference Gabata T, Kadoya M, Terayama N et al (2003) Groove pancreatic carcinomas: radiological and pathological findings. Eur Radiol 13:1679–1684CrossRefPubMed Gabata T, Kadoya M, Terayama N et al (2003) Groove pancreatic carcinomas: radiological and pathological findings. Eur Radiol 13:1679–1684CrossRefPubMed
35.
go back to reference Regent D, Laurent V, Antunes L et al (2002) Fibrous tissue(s): a key for lesion characterization in digestive diseases. J Radiol 83(2 Pt 2):292–312PubMed Regent D, Laurent V, Antunes L et al (2002) Fibrous tissue(s): a key for lesion characterization in digestive diseases. J Radiol 83(2 Pt 2):292–312PubMed
36.
37.
go back to reference Irie H, Honda H, Kuroiwa T et al (1998) MRI of groove pancreatitis. J Comput Assist Tomogr 22:651–655CrossRefPubMed Irie H, Honda H, Kuroiwa T et al (1998) MRI of groove pancreatitis. J Comput Assist Tomogr 22:651–655CrossRefPubMed
38.
go back to reference Procacci C, Graziani R, Zamboni G et al (1997) Cystic dystrophy of the duodenal wall: radiologic findings. Radiology 205:741–747PubMed Procacci C, Graziani R, Zamboni G et al (1997) Cystic dystrophy of the duodenal wall: radiologic findings. Radiology 205:741–747PubMed
39.
go back to reference Hwang JY, Park KS, Cho KB et al (2003) Segmental groove pancreatitis: report of one case. Korean J Intern Med 18:234–237PubMed Hwang JY, Park KS, Cho KB et al (2003) Segmental groove pancreatitis: report of one case. Korean J Intern Med 18:234–237PubMed
40.
go back to reference Basili E, Allemand I, Ville E et al (2001) Lanreotide acetate may cure cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 25:1108–1111PubMed Basili E, Allemand I, Ville E et al (2001) Lanreotide acetate may cure cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 25:1108–1111PubMed
41.
go back to reference Arisaka Y, Tada H, Hongoh Y et al (1998) A case of groove pancreatitis successfully treated with conservative therapy. Nippon Shokakibyo Gakkai Zasshi 95:1157–1161PubMed Arisaka Y, Tada H, Hongoh Y et al (1998) A case of groove pancreatitis successfully treated with conservative therapy. Nippon Shokakibyo Gakkai Zasshi 95:1157–1161PubMed
42.
go back to reference de Parades V, Roulot D, Palazzo L et al (1996) Treatment with octreotide of stenosing cystic dystrophy on heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 20:601–604PubMed de Parades V, Roulot D, Palazzo L et al (1996) Treatment with octreotide of stenosing cystic dystrophy on heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 20:601–604PubMed
43.
go back to reference Pessaux P, Lada P, Etienne S et al (2006) Duodenopancreatectomy for cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 30:24–28PubMedCrossRef Pessaux P, Lada P, Etienne S et al (2006) Duodenopancreatectomy for cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 30:24–28PubMedCrossRef
44.
go back to reference Isayama H, Kawabe T, Komatsu Y et al (2005) Successful treatment for groove pancreatitis by endoscopic drainage via the minor papilla. Gastrointest Endosc 61:175–178CrossRefPubMed Isayama H, Kawabe T, Komatsu Y et al (2005) Successful treatment for groove pancreatitis by endoscopic drainage via the minor papilla. Gastrointest Endosc 61:175–178CrossRefPubMed
45.
go back to reference Beaulieu S, Vitte RL, Le Corguille M et al (2004) Endoscopic drainage of cystic dystrophy of the duodenal wall: report of three cases. Gastroenterol Clin Biol 28:1159–1164PubMed Beaulieu S, Vitte RL, Le Corguille M et al (2004) Endoscopic drainage of cystic dystrophy of the duodenal wall: report of three cases. Gastroenterol Clin Biol 28:1159–1164PubMed
46.
go back to reference Fekete F, Noun R, Sauvanet A et al (1996) Pseudotumor developing in heterotopic pancreas. World J Surg 20:295–298CrossRefPubMed Fekete F, Noun R, Sauvanet A et al (1996) Pseudotumor developing in heterotopic pancreas. World J Surg 20:295–298CrossRefPubMed
47.
go back to reference Munthali Lovemore CE, Hsu JT, Chiu CT et al (2001) Groove pancreatitis: case report and literature review. Chang Gung Med J 24:512–516PubMed Munthali Lovemore CE, Hsu JT, Chiu CT et al (2001) Groove pancreatitis: case report and literature review. Chang Gung Med J 24:512–516PubMed
48.
go back to reference Di Sebastiano P, di Mola FF, Buchler MW et al (2004) Pathogenesis of pain in chronic pancreatitis. Dig Dis 22:267–272CrossRefPubMed Di Sebastiano P, di Mola FF, Buchler MW et al (2004) Pathogenesis of pain in chronic pancreatitis. Dig Dis 22:267–272CrossRefPubMed
49.
go back to reference Bassi C, Falconi M, Molinari E et al (2005) Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative study. Ann Surg 242:767–771; discussion 771–763CrossRefPubMed Bassi C, Falconi M, Molinari E et al (2005) Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative study. Ann Surg 242:767–771; discussion 771–763CrossRefPubMed
50.
go back to reference Bassi C, Falconi M, Molinari E et al (2003) Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial. Surgery 134:766–771CrossRefPubMed Bassi C, Falconi M, Molinari E et al (2003) Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial. Surgery 134:766–771CrossRefPubMed
51.
go back to reference Bassi C, Falconi M, Salvia R et al (2001) Management of complications after pancreaticoduodenectomy in a high volume centre: results on 150 consecutive patients. Dig Surg 18:453–457; discussion 458CrossRefPubMed Bassi C, Falconi M, Salvia R et al (2001) Management of complications after pancreaticoduodenectomy in a high volume centre: results on 150 consecutive patients. Dig Surg 18:453–457; discussion 458CrossRefPubMed
Metadata
Title
“Paraduodenal” Pancreatitis: Results of Surgery on 58 Consecutives Patients from a Single Institution
Authors
L. Casetti
C. Bassi
R. Salvia
G. Butturini
R. Graziani
M. Falconi
L. Frulloni
S. Crippa
G. Zamboni
P. Pederzoli
Publication date
01-12-2009
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 12/2009
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-009-0238-5

Other articles of this Issue 12/2009

World Journal of Surgery 12/2009 Go to the issue