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World Journal of Surgery

Published in:

01-03-2007

Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia

Results of a Randomized Controlled Trial

Authors: S. Kostic, A. Kjellin, M. Ruth, H. Lönroth, E. Johnsson, M. Andersson, L. Lundell

Published in: World Journal of Surgery | Issue 3/2007

Abstract

Background

The most effective therapeutic strategy in newly diagnosed achalasia is yet to be established. Therefore we designed a study in which pneumatic dilatation was compared to laparoscopic cardiomyotomy to which was added a partial posterior fundoplication.

Patients and Results

A series of 51 patients (24 males, mean age 44 years) were randomly allocated to the therapeutic modalities (dilatation = 26, surgery = 25). All patients were followed for at least 12 months, and during that period the pneumatic dilatations strategy had significantly more treatment failures (P = 0.04). Only minor differences emerged between the study groups when symptoms, dysphagia scorings, and quality-of-life assessments were evaluated 12 months after initiation of therapy.

Conclusions

Laparoscopic myotomy was found to be superior to an endoscopic balloon dilatation strategy in the treatment of achalasia when studied during the first 12 months after treatment.

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Title: Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia
Results of a Randomized Controlled Trial
Authors: S. Kostic
A. Kjellin
M. Ruth
H. Lönroth
E. Johnsson
M. Andersson
L. Lundell
Publication date: 01-03-2007
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 3/2007
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-006-0600-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia

Results of a Randomized Controlled Trial

Abstract

Background

Patients and Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Patients and Results

Conclusions

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