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Published in: Aesthetic Plastic Surgery 6/2023

21-08-2023 | Autologous Fat | Review

Autologous Fat Grafting for Functional and Aesthetic Improvement in Patients with Head and Neck Cancer: A Systematic Review

Authors: Yu Wang, Lili Hou, Mingyi Wang, Fuping Xiang, Xiaomei Zhao, Meizhen Qian

Published in: Aesthetic Plastic Surgery | Issue 6/2023

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Abstract

Introduction

The efficacy and safety of autologous fat grafting for use in oncology patients are controversial. Patients with head and neck cancer have complex anatomy and require reconstructive repair of the head and neck after comprehensive treatment. The limited additional aesthetic and functional studies on the use of autologous fat fillers in patients with head and neck cancer are unclear. This study systematically evaluates the additional function of autologous fat fillers in the head and neck and systematically reviews issues related to autologous fat grafting after comprehensive head and neck cancer treatment, including current indications, techniques, potential complications, graft survival, and patient satisfaction.

Methods

A systematic literature review was performed using PubMed, The Cochrane Library, EMBASE, and Web of Science (last accessed on January 9, 2023).

Results

A total of 249 cases of autologous fat fillers in patients with head and neck cancer were reported in 10 clinical publications. Observations were based mainly on subjective physician and patient evaluation indicators, and all studies reported the beneficial effects of autologous fat fillers on aesthetics and function after treatment for head and neck cancer.

Conclusions

Autologous fat fillers are effective in improving the aesthetics and function of head and neck cancer, and due to the limitations of the original study, future studies with large samples are needed to support this. PROSPERO registration number is CRD42020222870.

Level of Evidence III

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Literature
1.
go back to reference Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I (2021) Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209–249CrossRefPubMed Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I (2021) Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209–249CrossRefPubMed
4.
14.
go back to reference Howick J, Chalmers I, Glasziou P (2011) OCEBM levels of evidence working group ‘The Oxford 2011 levels of evidence. Oxford Centre for Evidence-Based Medicine, Oxford Howick J, Chalmers I, Glasziou P (2011) OCEBM levels of evidence working group ‘The Oxford 2011 levels of evidence. Oxford Centre for Evidence-Based Medicine, Oxford
Metadata
Title
Autologous Fat Grafting for Functional and Aesthetic Improvement in Patients with Head and Neck Cancer: A Systematic Review
Authors
Yu Wang
Lili Hou
Mingyi Wang
Fuping Xiang
Xiaomei Zhao
Meizhen Qian
Publication date
21-08-2023
Publisher
Springer US
Published in
Aesthetic Plastic Surgery / Issue 6/2023
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-023-03331-0

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