Skip to main content
Top
Published in: Aesthetic Plastic Surgery 3/2021

01-06-2021 | Mastitis | Original Article

Management of Granulomatous Mastitis Following Aesthetic Breast Surgery

Authors: Mustafa Berkesoglu, Ahmet Dag, Ferah Tuncel, Recep Okan Ustun

Published in: Aesthetic Plastic Surgery | Issue 3/2021

Login to get access

Abstract

Background

Granulomatous mastitis (GM) is not among the well-known diseases in the field of aesthetic breast surgery (ABS). The clinical presentation of GM resembles infectious diseases or malignancies, but the management of these diseases is quite different. In this study, we aimed to present the management of GM in patients who underwent ABS.

Methods

In this study, patients with GM (n = 65) and patients who underwent ABS (n = 531) were evaluated. A total of six GM patients with a history of ABS were included in the study between January 1, 2010, and January 1, 2019. The data were collected retrospectively. The quantitative variables are shown as medians (minimum–maximum), and categorical variables are shown as numbers and percentages (%).

Results

Median duration of disease onset after the ABS was 16 (8–38) months. After the diagnosis of GM was obtained, all patients received steroid treatment. Median steroid treatment duration was 10 (8–20) weeks. Methotrexate was administered in two patients due to persistent breast mass and steroid side effect. Surgical excision was performed in three patients with wide excision. No patient needed further surgery such as mastectomy. Median follow-up period was 37.5 (18–70) months.

Conclusion

This is the first study to declare GM in patients who underwent ABS. Atypical clinical presentation such as breast abscess, mass or fistula after ABS should alert the surgeon about GM. Unlike other mastitis, the primary treatment of this rare disease is steroid and immunosuppressive treatment. Insufficient knowledge about GM can lead to unnecessary surgeries or breast loss.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Literature
1.
go back to reference Fischer JP, Cleveland EC, Shang EK, Nelson JA, Serletti JM (2014) Complications following reduction mammaplasty: a review of 3538 cases from the 2005–2010 NSQIP data sets. Aesthet Surg J 34:66–73CrossRef Fischer JP, Cleveland EC, Shang EK, Nelson JA, Serletti JM (2014) Complications following reduction mammaplasty: a review of 3538 cases from the 2005–2010 NSQIP data sets. Aesthet Surg J 34:66–73CrossRef
2.
go back to reference Spear SL, Dayan JH, Clemens MW (2009) Augmentation mastopexy. Clin Plast Surg 36:105–115CrossRef Spear SL, Dayan JH, Clemens MW (2009) Augmentation mastopexy. Clin Plast Surg 36:105–115CrossRef
3.
go back to reference Gurleyik G, Aktekin A, Aker F, Karagulle H, Saglam A (2012) Medical and surgical treatment of idiopathic granulomatous lobular mastitis: a benign inflammatory disease mimicking invasive carcinoma. J Breast Cancer 15:119–123CrossRef Gurleyik G, Aktekin A, Aker F, Karagulle H, Saglam A (2012) Medical and surgical treatment of idiopathic granulomatous lobular mastitis: a benign inflammatory disease mimicking invasive carcinoma. J Breast Cancer 15:119–123CrossRef
4.
go back to reference de Vita R, Buccheri EM, Villanucci A, Ragusa LA (2019) Breast asymmetry, classification, and algorithm of treatment: our experience. Aesthet Plast Surg 43(6):1439–1450CrossRef de Vita R, Buccheri EM, Villanucci A, Ragusa LA (2019) Breast asymmetry, classification, and algorithm of treatment: our experience. Aesthet Plast Surg 43(6):1439–1450CrossRef
5.
go back to reference Nava MB, Rancati A, Angrigiani C, Angrigiani C, Catanuto G, Rocco N (2017) How to prevent complications in breast augmentation. Gland Surg 6:210–217CrossRef Nava MB, Rancati A, Angrigiani C, Angrigiani C, Catanuto G, Rocco N (2017) How to prevent complications in breast augmentation. Gland Surg 6:210–217CrossRef
6.
7.
go back to reference Wirthmann AE, Welsch L, Wellenbrock SV, Kasper L, Schlosshauer T, Bozkurt A, Hüttinger S, Rieger UM (2018) Reduction mammoplasty in adolescents and elderly: a ten year case series analyzing age related outcome with focus on safety and complications. J Plast Reconstr Aesthet Surg 71:377–383CrossRef Wirthmann AE, Welsch L, Wellenbrock SV, Kasper L, Schlosshauer T, Bozkurt A, Hüttinger S, Rieger UM (2018) Reduction mammoplasty in adolescents and elderly: a ten year case series analyzing age related outcome with focus on safety and complications. J Plast Reconstr Aesthet Surg 71:377–383CrossRef
8.
go back to reference Reisman NR (2016) Medicolegal issues in breast reduction. Clin Plast Surg 43:441–444CrossRef Reisman NR (2016) Medicolegal issues in breast reduction. Clin Plast Surg 43:441–444CrossRef
9.
go back to reference Atak T, Sagiroglu J, Eren T, Ozemir IA, Alimoglu O (2015) Strategies to treat idiopathic granulomatous mastitis: retrospective analysis of 40 patients. Breast Dis 35:19–24CrossRef Atak T, Sagiroglu J, Eren T, Ozemir IA, Alimoglu O (2015) Strategies to treat idiopathic granulomatous mastitis: retrospective analysis of 40 patients. Breast Dis 35:19–24CrossRef
10.
go back to reference Altintoprak F, Kivilcim T, Ozkan OV (2014) Aetiology of idiopathic granulomatous mastitis. World J Clin Cases 16:852–858CrossRef Altintoprak F, Kivilcim T, Ozkan OV (2014) Aetiology of idiopathic granulomatous mastitis. World J Clin Cases 16:852–858CrossRef
11.
go back to reference Cohen WA, Homel P, Patel NP (2016) Does time affect patient satisfaction and health-related quality of life after reduction mammoplasty? Eplasty 21(16):e7 Cohen WA, Homel P, Patel NP (2016) Does time affect patient satisfaction and health-related quality of life after reduction mammoplasty? Eplasty 21(16):e7
12.
go back to reference Honigman RJ, Phillips KA, Castle DJ (2004) A review of psychosocial outcomes for patients seeking cosmetic surgery. Plast Reconst Surg 113:1229–1237CrossRef Honigman RJ, Phillips KA, Castle DJ (2004) A review of psychosocial outcomes for patients seeking cosmetic surgery. Plast Reconst Surg 113:1229–1237CrossRef
13.
go back to reference Klassen AF, Pusic AL, Scott A, Klok J, Cano SJ (2009) Satisfaction and quality of life in women who undergo breast surgery: a qualitative study. BMC Womens Health 9:11CrossRef Klassen AF, Pusic AL, Scott A, Klok J, Cano SJ (2009) Satisfaction and quality of life in women who undergo breast surgery: a qualitative study. BMC Womens Health 9:11CrossRef
14.
go back to reference Purohit S (2008) Reduction mammoplasty. Indian J Plast Surg 41(Suppl 01):64–79 Purohit S (2008) Reduction mammoplasty. Indian J Plast Surg 41(Suppl 01):64–79
15.
go back to reference Kessler E, Wolloch Y (1972) Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol 58:642–646CrossRef Kessler E, Wolloch Y (1972) Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol 58:642–646CrossRef
16.
go back to reference Atalay C, Kızıltan G, Ozaslan C, Pak I (2011) Idiopathic granulomatous mastitis. J Breast Health 7:203–206 Atalay C, Kızıltan G, Ozaslan C, Pak I (2011) Idiopathic granulomatous mastitis. J Breast Health 7:203–206
17.
go back to reference Aydın HO, Baykal A, Konan A, Kaynaroglu V (2019) Idiopathic granulomatous mastitis: factors influencing recovery and recurrence. Eur Res J 5:768–775 Aydın HO, Baykal A, Konan A, Kaynaroglu V (2019) Idiopathic granulomatous mastitis: factors influencing recovery and recurrence. Eur Res J 5:768–775
18.
go back to reference Pluguez-Turull CW, Nanyes JE, Quintero CJ, Alizai H, Mais DD, Kist KA, Dornbluth NC (2018) Idiopathic granulomatous mastitis: manifestations at multimodality imaging and pitfalls. Radiographics 38:330–356CrossRef Pluguez-Turull CW, Nanyes JE, Quintero CJ, Alizai H, Mais DD, Kist KA, Dornbluth NC (2018) Idiopathic granulomatous mastitis: manifestations at multimodality imaging and pitfalls. Radiographics 38:330–356CrossRef
19.
go back to reference Özşen M, Tolunay Ş, Gökgöz MŞ (2018) Granulomatous lobular mastitis: clinicopathologic presentation of 90 cases. Age 34:215–219 Özşen M, Tolunay Ş, Gökgöz MŞ (2018) Granulomatous lobular mastitis: clinicopathologic presentation of 90 cases. Age 34:215–219
20.
go back to reference Hoda SA (2014) Inflammatory and reactive tumors. In: Hoda SA, Brogi E, Koerner FC, Rosen PP (eds) Rosen’s breast pathology, 4th edn. Lippincott Williams and Wilkins, Philadelphia, pp 37–77 Hoda SA (2014) Inflammatory and reactive tumors. In: Hoda SA, Brogi E, Koerner FC, Rosen PP (eds) Rosen’s breast pathology, 4th edn. Lippincott Williams and Wilkins, Philadelphia, pp 37–77
21.
go back to reference Lester SC, Hicks DG (2016) Inflammatory lesions: granulomatous lobuler mastitis. In: Lester SC, Hicks DG (eds) Diagnostic pathology: breast, 2nd edn. Elsevier, Salt Lake City, UT, pp 596–601 Lester SC, Hicks DG (2016) Inflammatory lesions: granulomatous lobuler mastitis. In: Lester SC, Hicks DG (eds) Diagnostic pathology: breast, 2nd edn. Elsevier, Salt Lake City, UT, pp 596–601
22.
go back to reference Wolfrum A, Kümmel S, Theuerkauf I, Pelz E, Reinisch M (2018) Granulomatous mastitis: a therapeutic and diagnostic challenge. Breast Care (Basel) 13:413–418CrossRef Wolfrum A, Kümmel S, Theuerkauf I, Pelz E, Reinisch M (2018) Granulomatous mastitis: a therapeutic and diagnostic challenge. Breast Care (Basel) 13:413–418CrossRef
23.
go back to reference Illman JE, Terra SB, Clapp AJ, Hunt KN, Fazzio RT, Shah SS, Glazebrook KN (2018) Granulomatous diseases of the breast and axilla: radiological findings with pathological correlation. Insights Imaging 9:59–71CrossRef Illman JE, Terra SB, Clapp AJ, Hunt KN, Fazzio RT, Shah SS, Glazebrook KN (2018) Granulomatous diseases of the breast and axilla: radiological findings with pathological correlation. Insights Imaging 9:59–71CrossRef
24.
go back to reference Bakaris S, Yuksel M, Ciragil P, Guven MA, Ezberci F, Bulbuloglu E (2006) Granulomatous mastitis including breast tuberculosis and idiopathic lobular granulomatous mastitis. Can J Surg 49:427–430PubMedPubMedCentral Bakaris S, Yuksel M, Ciragil P, Guven MA, Ezberci F, Bulbuloglu E (2006) Granulomatous mastitis including breast tuberculosis and idiopathic lobular granulomatous mastitis. Can J Surg 49:427–430PubMedPubMedCentral
25.
go back to reference Vural S, Ertop P, Ceyhan K, Şanli H (2017) An unusual cause of oligoarthritis and erythema nodosum: idiopathic granulomatous mastitis. Arch Rheumatol 32:71–75CrossRef Vural S, Ertop P, Ceyhan K, Şanli H (2017) An unusual cause of oligoarthritis and erythema nodosum: idiopathic granulomatous mastitis. Arch Rheumatol 32:71–75CrossRef
26.
go back to reference Wong T, Lo LW, Fung PY, Lai HYM, She HLH, Ng WKC, Kwok KMK, Lee CM (2016) Magnetic resonance imaging of breast augmentation: a pictorial review. Insights Imaging 7:399–410CrossRef Wong T, Lo LW, Fung PY, Lai HYM, She HLH, Ng WKC, Kwok KMK, Lee CM (2016) Magnetic resonance imaging of breast augmentation: a pictorial review. Insights Imaging 7:399–410CrossRef
27.
go back to reference Margolis NE, Morley C, Lotfi P, Shaylor SD, Palestrant S, Moy L, Melsaether AN (2014) Update on imaging of the postsurgical breast. Radiographics 34:642–660CrossRef Margolis NE, Morley C, Lotfi P, Shaylor SD, Palestrant S, Moy L, Melsaether AN (2014) Update on imaging of the postsurgical breast. Radiographics 34:642–660CrossRef
28.
go back to reference Velidedeoglu M, Kilic F, Mete B, Yemisen M, Celik V, Gazioglu E, Ferahman M, Ozaras R, Yilmaz MH, Aydogan F (2016) Bilateral idiopathic granulomatous mastitis. Asian J Surg 39:12–20CrossRef Velidedeoglu M, Kilic F, Mete B, Yemisen M, Celik V, Gazioglu E, Ferahman M, Ozaras R, Yilmaz MH, Aydogan F (2016) Bilateral idiopathic granulomatous mastitis. Asian J Surg 39:12–20CrossRef
29.
go back to reference Garcia-Rodiguez JA, Pattullo A (2013) Idiopathic granulomatous mastitis: a mimicking disease in a pregnant woman: a case report. BMC Res Notes 14:95CrossRef Garcia-Rodiguez JA, Pattullo A (2013) Idiopathic granulomatous mastitis: a mimicking disease in a pregnant woman: a case report. BMC Res Notes 14:95CrossRef
30.
go back to reference Néel A, Hello M, Cottereau A, Graveleau J, De Faucal P, Costedoat-Chalumeau N, Rondeau-Lutz M, Lavigne C, Chiche L, Hachulla E, Seiberras S, Cabane J, Tournemaine N, Hamidou M (2013) Long-term outcome in idiopathic granulomatous mastitis: a western multicentre study. QJM 106:433–441CrossRef Néel A, Hello M, Cottereau A, Graveleau J, De Faucal P, Costedoat-Chalumeau N, Rondeau-Lutz M, Lavigne C, Chiche L, Hachulla E, Seiberras S, Cabane J, Tournemaine N, Hamidou M (2013) Long-term outcome in idiopathic granulomatous mastitis: a western multicentre study. QJM 106:433–441CrossRef
Metadata
Title
Management of Granulomatous Mastitis Following Aesthetic Breast Surgery
Authors
Mustafa Berkesoglu
Ahmet Dag
Ferah Tuncel
Recep Okan Ustun
Publication date
01-06-2021
Publisher
Springer US
Published in
Aesthetic Plastic Surgery / Issue 3/2021
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-020-01992-9

Other articles of this Issue 3/2021

Aesthetic Plastic Surgery 3/2021 Go to the issue