Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Aesthetic Plastic Surgery
Published in: Aesthetic Plastic Surgery 4/2011

01-08-2011 | Original Article

A Novel Autologous Scaffold for Diced-cartilage Grafts in Dorsal Augmentation Rhinoplasty

Authors: Jamal M. Bullocks, Anthony Echo, Gerardo Guerra, Samuel Stal, Eser Yuksel

Published in: Aesthetic Plastic Surgery | Issue 4/2011

Login to get access

Abstract

Background

Diced-cartilage grafts have been used for dorsal nasal augmentation for several years with good results. However, compounds such as Surgicel and temporalis fascia used as a wrap have inherent problems associated with them, predominantly inflammation and graft resorption. An autologous carrier could provide stabilization of cartilage grafts while avoiding the complications seen with earlier techniques.

Methods

In our patients, a malleable construct was used for dorsal nasal augmentation in which autologous diced-cartilage grafts were stabilized with autologous tissue glue (ATG) created from platelet-rich plasma (platelet gel) and platelet-poor plasma (fibrin glue).

Results

A prospective analysis of 68 patients, who underwent dorsal nasal augmentation utilizing ATG and diced-cartilage grafts between 2005 and 2008, were included in the study. Although there was notable maintenance of the dorsal height, no complications occurred that required explantation over a mean follow-up of 15 months.

Conclusion

The use of ATG to stabilize diced-cartilage grafts is a safe, reliable technique for dorsal nasal augmentation. The platelet gel provides growth factors while the fibrin glue creates a scaffold that allows stabilization and diffusion of nutrients to the cartilage graft.
Literature
1.
Erol OO (2000) The Turkish delight: a pliable graft for rhinoplasty. Plast Reconstr Surg 105:2229–2241PubMedCrossRef
2.
Guerrorosantos J, Trananino C, Guerroerosantos F (2006) Multifragmented cartilage wrapped with fascia in augmentation rhinoplasty. Plast Reconstr Surg 117(3):804–812 discussion 813–816CrossRef
3.
Brenner KA, McConnell MP, Evans GR, Calvert JW (2006) Survival of diced cartilage grafts: an experimental study. Plast Reconstr Surg 117(1):105–115PubMedCrossRef
4.
Daniel RK, Calvert LW (2004) Diced cartilage grafts in rhinoplasty surgery. Plast Reconstr Surg 113(7):2156–2171PubMedCrossRef
5.
6.
Araco A, Gravante G, Araco F, Castri F, Delogu D, Filingeri V, Casciani CU, Cervelli V (2006) Autologous cartilage graft rhinoplasties. Aesthetic Plast Surg 30(2):169–174PubMedCrossRef
7.
Erlich MA, Parhiscar A (2003) Nasal dorsal augmentation with silicone implants. Facial Plast Surg 19(4):325–330PubMedCrossRef
8.
9.
Zeng Y, Wu W, Yu H, Yang J, Chen G (2002) Silicone implant in augmentation rhinoplasty. Ann Plast Surg 49(5):495–499PubMedCrossRef
10.
Owa AO, Zaman A, Farrell RW, Bull TR (1999) An unusual complication of augmentation rhinoplasty: Late displacement of dorsal nasal splint. J Laryngol Otol 113:358–360PubMedCrossRef
11.
Tham C, Lai YL, Weng CJ, Chen YR (2005) Silicone augmentation rhinoplasty in an oriental population. Ann Plast Surg 54(1):1–5 discussion 6–7PubMedCrossRef
12.
Romo T 3rd, Sclafani AP, Jacono AA (2000) Nasal reconstruction using porous polyethylene implants. Facial Plast Surg 16(1):55–61PubMedCrossRef
13.
Niechajev I (1999) Porous polyethylene implants for nasal reconstruction: clinical and histologic studies. Aesthetic Plast Surg 23:395–402PubMedCrossRef
14.
Lohuis PJ, Watts SJ, Vuyk HD (2001) Augmentation of the nasal dorsum using Gore-Tex: intermediate results of a retrospective analysis of experience in 66 patients. Clin Otolaryngol Allied Sci 26(3):214–217PubMedCrossRef
15.
Ham J, Miller PJ (2003) Expanded polytetrafluoroethylene implants in rhinoplasty: literature review, operative techniques, and outcome. Facial Plast Surg 19(4):331–339PubMedCrossRef
16.
Sachs ME (1987) ‘Tissue clay’. A new technique for augmentation rhinoplasty. Arch Otolaryngol Head Neck Surg 113(3):289–291PubMedCrossRef
17.
Gryskiewicz JM (2005) Waste not, want not: the use of AlloDerm in secondary rhinoplasty. Plast Reconstr Surg 116(7):1999–2004PubMedCrossRef
18.
Demirkan F, Arslan E, Unal S, Aksoy A (2003) Irradiated homologous costal cartilage: versatile grafting material for rhinoplasty. Aesthetic Plast Surg 27(3):213–220PubMedCrossRef
19.
Gubisch W (1992) Implants in rhinoplasty: value and indications. Handchir Mikrochir Plast Chir 24:38–45 [in German]PubMed
20.
Jung DH, Choi SH, Moon HJ, Chung IH, Im JH, Lam SM (2004) A cadaveric analysis of the ideal costal cartilage graft for Asian rhinoplasty. Plast Reconstr Surg 114(2):545–550PubMedCrossRef
21.
Sarukawa S, Sugawara Y, Harii K (2004) Cephalometric long-term follow-up of nasal augmentation using iliac bone graft. J Craniomaxillofac Surg 32(4):233–235PubMedCrossRef
22.
Cannella DM, Hopkins LN (1990) Superior sagittal sinus laceration complicating an autogenous calvarial bone graft harvest, case report. J Oral Maxillofac Surg 48:741–743PubMedCrossRef
23.
Young VL, Schuster RH, Harris LW (1990) Intracerebral hematoma complicating split calvarial bone graft harvesting. Plast Reconstr Surg 86:763–765PubMedCrossRef
24.
Karacaoglan N, Uysal OA (1998) Use of iliac bone graft for saddle nose deformity. Auris Nasus Larynx 25(1):49–57PubMedCrossRef
25.
Baker TM, Courtiss EH (1994) Temporalis fascia grafts in open secondary rhinoplasty. Plast Reconstr Surg 93:802–810PubMedCrossRef
26.
Miller TA (1988) Temporalis fascia grafts for facial and nasal contour augmentation. Plast Reconstr Surg 81(4):524–533PubMedCrossRef
27.
Erdogan B, Tuncel A, Adanali G, Deren O, Ayhan M (2003) Augmentation rhinoplasty with dermal graft and review of the literature. Plast Reconstr Surg 111(6):2060–2068PubMedCrossRef
28.
Bateman N, Jones NS (2000) Retrospective review of augmentation rhinoplasties using autologous cartilage grafts. J Laryngol Otol 114:514–518PubMed
29.
Ortiz-Monasterio F, Olmedo A, Oscoy LO (1981) The use of cartilage grafts in primary aesthetic rhinoplasty. Plast Reconstr Surg 67:597–605PubMedCrossRef
30.
Celik M, Haliloglu T, Baycin N (2004) Bone chips and diced cartilage: an anatomically adopted graft for the nasal dorsum. Aesthetic Plast Surg 28(1):8–12PubMedCrossRef
31.
Calvert JW, Brenner K, DaCosta-Iyer M, Evans GR, Daniel RK (2006) Histological analysis of human diced cartilage grafts. Plast Reconstr Surg 118(1):230–236PubMedCrossRef
32.
Ahmed TA, Dare EV, Hincke M (2008) Fibrin: a versatile scaffold for tissue engineering applications. Tissue Eng Part B Rev 14(2):199–215PubMedCrossRef
33.
Man D, Plosker H, Winland-Brown JE (2001) The use of autologous platelet-rich plasma (platelet gel) and autologous platelet-poor plasma (fibrin glue) in cosmetic surgery. Plast Reconstr Surg 107(1):229–237PubMedCrossRef
34.
Sampson S, Gerhardt M, Mandelbaum B (2008) Platelet rich plasma injection grafts for musculoskeletal injuries: a review. Curr Rev Musculoskelet Med 1(3–4):165–174PubMedCrossRef
35.
Pietrzak W, Eppley B (2005) Scientific foundations platelet rich plasma: biology and new technology. J Craniofac Surg 16(6):1043–1054PubMedCrossRef
36.
Marx R, Garg A (2005) Dental and craniofacial applications of platelet-rich plasma. Quintessence Publishing Co., Inc., Carol Stream
37.
Everts P, Knape J, Weirich G, Schönberger JP, Hoffmann J, Overdevest EP, Box HA, van Zundert A (2006) Platelet-rich plasma and platelet gel: a review. J Extra Corpor Technol 38:174–187PubMed
38.
Wu W, Chen F, Liu Y, Ma Q, Mao T (2007) Autologous injectable tissue-engineered cartilage by using platelet-rich plasma: experimental study in rabbit model. J Oral Maxillofac Surg 65(10):1951–1957PubMedCrossRef
39.
Bendinelli P, Matteucci E, Dogilotti G, Corsi MM, Banfi G, Maroni P, Desiderio MA (2010) Molecular basis of anti-inflammatory action of platelet-rich plasma on human chondrocytes: mechanism of NF-kB inhibition via HGF. J Cell Physiol 225(3):757–766PubMedCrossRef
40.
Kon E, Buda R, Filardo G et al (2010) Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Knee Surg Sports Traumatol Arthosc 18(4):472–479CrossRef
41.
Pierce GF, Mustoe TA, Lingelbach J et al (1989) Platelet derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms. J Cell Biol 109(1):429–440PubMedCrossRef
42.
Pierce GF, Mustoe TA, Altrock BW, Deuel TF, Thomason A (1991) Role of platelet-derived growth factor in wound healing. J Cell Biochem 45(4):319–326PubMedCrossRef
43.
Hunziker EB, Driesang IM, Morris EA (2001) Chondrogenesis in cartilage repair is induced by members of the transforming growth factor-beta superfamily. Clin Orthop Relat Res 391:S171–181PubMedCrossRef
44.
Ishii I, Mizuta H, Sei A et al (2007) Healing of full-thickness defects of the articular cartilage in rabbits using fibroblast growth factor-2 and fibrin sealant. J Bone Joint Surg Br 89(5):693–700PubMedCrossRef
45.
Spotnitz WD (2010) Fibrin sealant: past, present, and future: a brief review. World J Surg 34(4):632–634PubMedCrossRef
46.
Tawes RL Jr, Sydorak GR, DuVall TB (1994) Autologous fibrin glue: the last step in operative hemostasis. Am J Surg 168(2):120–122PubMedCrossRef
47.
Schense JC, Hubbell JA (1999) Cross-linking exogenous bifunctional peptides into fibrin gels with factor XIIIa. Bioconjug Chem 10(1):75–81PubMedCrossRef
48.
Rosso F, Marino G, Giordano A, Barbarisi M, Parmeggiani D, Barbarisi A (2005) Smart materials as scaffolds for tissue engineering (review). J Cell Physiol 203(3):465–470PubMedCrossRef
49.
50.
Diesen DL, Lawson JH (2008) Bovine thrombin: history, use, and risk in the surgical patient. Vascular 16(Suppl 1):S29–S36PubMed
51.
Ortel TL, Mercer MC, Thames EH, Moore KD, Lawson JH (2001) Immunologic impact and clinic outcomes after surgical exposure to bovine thrombin. Ann Surg 233(1):88–96PubMedCrossRef
52.
Ofosu FA, Crean S, Reynolds MW (2009) A safety review of topical bovine thrombin-induced generation of antibodies to bovine proteins. Clin Ther 31(4):679–691PubMedCrossRef
53.
Randleman CD Jr, Singla NK, Renkens KL, Souza S, Pribble JP, Alexander WA (2010) Persistence of antibodies to the topical hemostat bovine thrombin. J Am Coll Surg 211(6):798–803PubMedCrossRef
Metadata
Title
A Novel Autologous Scaffold for Diced-cartilage Grafts in Dorsal Augmentation Rhinoplasty
Authors
Jamal M. Bullocks
Anthony Echo
Gerardo Guerra
Samuel Stal
Eser Yuksel
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
Aesthetic Plastic Surgery / Issue 4/2011
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-011-9725-9

Other articles of this Issue 4/2011

Aesthetic Plastic Surgery 4/2011 Go to the issue

Letter

How Important Is “Pseudogynecomastia”?

Letter to the Editor

Bidirectional Barbed Suture Migration: A Unique Complication After Intracuticular Closure

Letter to the Editor

Endoscopically Assisted Triple-Suture Midface Lift: A Refined Cable-Suture Technique

Original Article

Mandible Changes Evaluated by Computed Tomography Following Botulinum Toxin A Injections in Square-faced Patients

Original Article

The Facial Autologous Muscular Injection (FAMI) Procedure: An Anatomically Targeted Deep Multiplane Autologous Fat-Grafting Technique Using Principles of Facial Fat Injection

Innovative Technique

Syringe-Delivered Tumescent Anesthesia Made Easier