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Published in: International Orthopaedics 3/2010

01-03-2010 | Original Paper

Comparison of various surgical methods in the treatment of implant-related infection

Authors: Muhittin Şener, Cemal Kazimoglu, Hasan Karapınar, İzge Günal, İlhan Afşar, Aslı Gamze Karataş Şener

Published in: International Orthopaedics | Issue 3/2010

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Abstract

The treatment of implant-related infections is troublesome. This study was conducted to compare the effectiveness of three different surgical modalities in the treatment of implant-related infection. A total of 32 Wistar albino rats were randomised into four groups after the establishment of implant-related infection: no treatment, surgical débridement, antibiotic-loaded bone cement and antibiotic-loaded autogenous bone. Microbiological colony counts were made at the sixth week in order to evaluate the effectiveness of of the treatments. The antibiotic-loaded bone cement group revealed superior results compared with the other groups in terms of reduction of microbiological colonies. Three animals in the bone cement group revealed extensive infection. Although antibiotic-loaded bone cement showed superiority over other treatment modalities, it should be employed after an unsuccessful trial of débridement because of the risk of extensive infection.
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Metadata
Title
Comparison of various surgical methods in the treatment of implant-related infection
Authors
Muhittin Şener
Cemal Kazimoglu
Hasan Karapınar
İzge Günal
İlhan Afşar
Aslı Gamze Karataş Şener
Publication date
01-03-2010
Publisher
Springer-Verlag
Published in
International Orthopaedics / Issue 3/2010
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-009-0750-0

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