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Published in: International Orthopaedics 3/2009

01-06-2009 | Original Paper

Reconstruction of large defects in vertebral osteomyelitis with expandable titanium cages

Authors: Yohan Robinson, Sven Kevin Tschoeke, Ralph Kayser, Heinrich Boehm, Christoph E. Heyde

Published in: International Orthopaedics | Issue 3/2009

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Abstract

The purpose of this study was to investigate the outcome of expandable titanium cage implantation in large defects caused by acute vertebral osteomyelitis. Twenty-five patients with acute single or multilevel spondylodiscitis were treated after radical débridement and posterior instrumentation with an anterior expandable titanium cage and bone grafting. Clinical, laboratory and radiological follow-up continued for 36 months. Within the postoperative course there was no recurrence of spinal infection. The final radiological examination showed successful fusion in all cases without implant loosening or failure. At the final follow-up after 36 months the Oswestry Disability Index was 23 ± 14 and the pain visual analogue scale 2.1 ± 1.7. This study reveals healing and improved function after expandable titanium cage implantation in all patients. Prerequisites for optimal healing include radical débridement, provision of stability for weight-bearing, adequate bone grafting and correction of deformity using rigid implants.
Literature
1.
go back to reference Aryan HE, Lu DC, Acosta FL Jr, Ames CP (2007) Corpectomy followed by the placement of instrumentation with titanium cages and recombinant human bone morphogenetic protein-2 for vertebral osteomyelitis. J Neurosurg Spine 6:23–30PubMedCrossRef Aryan HE, Lu DC, Acosta FL Jr, Ames CP (2007) Corpectomy followed by the placement of instrumentation with titanium cages and recombinant human bone morphogenetic protein-2 for vertebral osteomyelitis. J Neurosurg Spine 6:23–30PubMedCrossRef
2.
go back to reference Fayazi AH, Ludwig SC, Dabbah M, Bryan Butler R, Gelb DE (2004) Preliminary results of staged anterior debridement and reconstruction using titanium mesh cages in the treatment of thoracolumbar vertebral osteomyelitis. Spine J 4:388–395PubMedCrossRef Fayazi AH, Ludwig SC, Dabbah M, Bryan Butler R, Gelb DE (2004) Preliminary results of staged anterior debridement and reconstruction using titanium mesh cages in the treatment of thoracolumbar vertebral osteomyelitis. Spine J 4:388–395PubMedCrossRef
3.
go back to reference Gibson MJ, Karpinski MRK, Slack RCB, Cowlishaw WA, Webb JK (1987) The penetration of antibiotics into the normal intervertebral disc. J Bone Joint Surg Br 69:784–786PubMed Gibson MJ, Karpinski MRK, Slack RCB, Cowlishaw WA, Webb JK (1987) The penetration of antibiotics into the normal intervertebral disc. J Bone Joint Surg Br 69:784–786PubMed
4.
go back to reference Ha KY, Chung YG, Ryoo SJ (2005) Adherence and biofilm formation of Staphylococcus epidermidis and Mycobacterium tuberculosis on various spinal implants. Spine 30:38–43PubMedCrossRef Ha KY, Chung YG, Ryoo SJ (2005) Adherence and biofilm formation of Staphylococcus epidermidis and Mycobacterium tuberculosis on various spinal implants. Spine 30:38–43PubMedCrossRef
5.
go back to reference Ha KY, Shin JH, Kim KW, Na KH (2007) The fate of anterior autogenous bone graft after anterior radical surgery with or without posterior instrumentation in the treatment of pyogenic lumbar spondylodiscitis. Spine 32:1856–1864PubMedCrossRef Ha KY, Shin JH, Kim KW, Na KH (2007) The fate of anterior autogenous bone graft after anterior radical surgery with or without posterior instrumentation in the treatment of pyogenic lumbar spondylodiscitis. Spine 32:1856–1864PubMedCrossRef
6.
go back to reference Hadjipavlou AG, Mader JT, Necessary JT, Muffoletto AJ (2000) Hematogenous pyogenic spinal infections and their surgical management. Spine 25:1668–1679PubMedCrossRef Hadjipavlou AG, Mader JT, Necessary JT, Muffoletto AJ (2000) Hematogenous pyogenic spinal infections and their surgical management. Spine 25:1668–1679PubMedCrossRef
7.
go back to reference Heyde CE, Boehm H, El Saghir H, Tschoke SK, Kayser R (2006) Surgical treatment of spondylodiscitis in the cervical spine: a minimum 2-year follow-up. Eur Spine J 15:1380–1387PubMedCrossRef Heyde CE, Boehm H, El Saghir H, Tschoke SK, Kayser R (2006) Surgical treatment of spondylodiscitis in the cervical spine: a minimum 2-year follow-up. Eur Spine J 15:1380–1387PubMedCrossRef
8.
go back to reference Klöckner C, Valencia R (2003) Sagittal alignment after anterior debridement and fusion with or without additional posterior instrumentation in the treatment of pyogenic and tuberculous spondylodiscitis. Spine 28:1036–1042PubMedCrossRef Klöckner C, Valencia R (2003) Sagittal alignment after anterior debridement and fusion with or without additional posterior instrumentation in the treatment of pyogenic and tuberculous spondylodiscitis. Spine 28:1036–1042PubMedCrossRef
9.
go back to reference Korovessis P, Petsinis G, Koureas G, Iliopoulos P, Zacharatos S (2006) One-stage combined surgery with mesh cages for treatment of septic spondylitis. Clin Orthop Relat Res 444:51–59PubMedCrossRef Korovessis P, Petsinis G, Koureas G, Iliopoulos P, Zacharatos S (2006) One-stage combined surgery with mesh cages for treatment of septic spondylitis. Clin Orthop Relat Res 444:51–59PubMedCrossRef
10.
go back to reference Korovessis P, Petsinis G, Koureas G, Iliopoulos P, Zacharatos S (2006) Anterior surgery with insertion of titanium mesh cage and posterior instrumented fusion performed sequentially on the same day under one anesthesia for septic spondylitis of thoracolumbar spine: is the use of titanium mesh cages safe? Spine 31:1014–1019PubMedCrossRef Korovessis P, Petsinis G, Koureas G, Iliopoulos P, Zacharatos S (2006) Anterior surgery with insertion of titanium mesh cage and posterior instrumented fusion performed sequentially on the same day under one anesthesia for septic spondylitis of thoracolumbar spine: is the use of titanium mesh cages safe? Spine 31:1014–1019PubMedCrossRef
11.
go back to reference Kuklo TR, Potter BK, Bell RS, Moquin RR, Rosner MK (2006) Single-stage treatment of pyogenic spinal infection with titanium mesh cages. J Spinal Disord Tech 19:376–382PubMedCrossRef Kuklo TR, Potter BK, Bell RS, Moquin RR, Rosner MK (2006) Single-stage treatment of pyogenic spinal infection with titanium mesh cages. J Spinal Disord Tech 19:376–382PubMedCrossRef
12.
go back to reference Lerner T, Schulte T, Bullmann V, Schneider M, Hackenberg L, Liljenqvist U (2006) Anterior column reconstruction using titanium ring cages in severe vertebral osteomyelitis. Eur J Trauma 32:227–237CrossRef Lerner T, Schulte T, Bullmann V, Schneider M, Hackenberg L, Liljenqvist U (2006) Anterior column reconstruction using titanium ring cages in severe vertebral osteomyelitis. Eur J Trauma 32:227–237CrossRef
13.
go back to reference McGuire RA, Eismont FJ (1994) The fate of autogenous bone graft in surgically treated pyogenic vertebral osteomyelitis. J Spinal Disord 7:206–215PubMedCrossRef McGuire RA, Eismont FJ (1994) The fate of autogenous bone graft in surgically treated pyogenic vertebral osteomyelitis. J Spinal Disord 7:206–215PubMedCrossRef
14.
go back to reference Ozturk C, Aydinli U, Vural R, Sehirlioglu A, Mutlu M (2007) Simultaneous versus sequential one-stage combined anterior and posterior spinal surgery for spinal infections (outcomes and complications). Int Orthop 31:363–366PubMedCrossRef Ozturk C, Aydinli U, Vural R, Sehirlioglu A, Mutlu M (2007) Simultaneous versus sequential one-stage combined anterior and posterior spinal surgery for spinal infections (outcomes and complications). Int Orthop 31:363–366PubMedCrossRef
15.
go back to reference Robinson Y, Reinke M, Kayser R, Ertel W, Heyde CE (2007) Postoperative multisegmental lumbar discitis treated by staged ventrodorsoventral intervention. Surg Infect (Larchmt) 8:529–534 Robinson Y, Reinke M, Kayser R, Ertel W, Heyde CE (2007) Postoperative multisegmental lumbar discitis treated by staged ventrodorsoventral intervention. Surg Infect (Larchmt) 8:529–534
16.
go back to reference Robinson Y, Tschöke SK, Finke T, Kayser R, Ertel W, Heyde CE (2008) Successful treatment of spondylodiscitis using titanium cages. Acta Orthop (in press) Robinson Y, Tschöke SK, Finke T, Kayser R, Ertel W, Heyde CE (2008) Successful treatment of spondylodiscitis using titanium cages. Acta Orthop (in press)
17.
go back to reference Ruf M, Stoltze D, Merk HR, Ames M, Harms J (2007) Treatment of vertebral osteomyelitis by radical debridement and stabilization using titanium mesh cages. Spine 32:E275–E280PubMedCrossRef Ruf M, Stoltze D, Merk HR, Ames M, Harms J (2007) Treatment of vertebral osteomyelitis by radical debridement and stabilization using titanium mesh cages. Spine 32:E275–E280PubMedCrossRef
18.
go back to reference Shad A, Shariff S, Fairbank J, Byren I, Teddy PJMAD, Cadoux-Hudson TAD (2003) Internal fixation for osteomyelitis of cervical spine: the issue of persistence of culture positive infection around the implants. Acta Neurochir (Wien) 145:957–960CrossRef Shad A, Shariff S, Fairbank J, Byren I, Teddy PJMAD, Cadoux-Hudson TAD (2003) Internal fixation for osteomyelitis of cervical spine: the issue of persistence of culture positive infection around the implants. Acta Neurochir (Wien) 145:957–960CrossRef
19.
go back to reference Stoltze D, Harms J (1999) Correction of posttraumatic deformities. Principles and methods (in German). Orthopade 28:731–745PubMedCrossRef Stoltze D, Harms J (1999) Correction of posttraumatic deformities. Principles and methods (in German). Orthopade 28:731–745PubMedCrossRef
21.
go back to reference Tay BKB, Deckey J, Hu SS (2002) Spinal infections. J Am Acad Orthop Surg 10:188–197PubMed Tay BKB, Deckey J, Hu SS (2002) Spinal infections. J Am Acad Orthop Surg 10:188–197PubMed
22.
go back to reference Ulmar B, Richter M, Kelsch G, Cakir B, Puhl W, Huch K (2005) Distractible vertebral body replacement for the thoracic and lumbar spine. Acta Orthop Belg 71:467–471PubMed Ulmar B, Richter M, Kelsch G, Cakir B, Puhl W, Huch K (2005) Distractible vertebral body replacement for the thoracic and lumbar spine. Acta Orthop Belg 71:467–471PubMed
23.
go back to reference Wlodarski KH, Galus R (2005) Histological aspects of bone fracture healing. Ortop Traumatol Rehabil 7:351–360 Wlodarski KH, Galus R (2005) Histological aspects of bone fracture healing. Ortop Traumatol Rehabil 7:351–360
Metadata
Title
Reconstruction of large defects in vertebral osteomyelitis with expandable titanium cages
Authors
Yohan Robinson
Sven Kevin Tschoeke
Ralph Kayser
Heinrich Boehm
Christoph E. Heyde
Publication date
01-06-2009
Publisher
Springer-Verlag
Published in
International Orthopaedics / Issue 3/2009
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-008-0567-2

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