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Published in: International Orthopaedics 6/2006

01-12-2006 | Original Paper

Comparison of the degenerative changes in weight-bearing joints following cementing or grafting techniques in giant cell tumour patients: medium-term results

Authors: K. Szalay, I. Antal, J. Kiss, M. Szendroi

Published in: International Orthopaedics | Issue 6/2006

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Abstract

The aim of this retrospective study was to compare and assess the effect of bone grafting and cementing techniques – two common applications used in the treatment of subchondral giant cell tumours of bone (GCTs) – on the development of degenerative changes in the weight-bearing joints of the lower extremity. Eighty patients were included in this follow-up study, 44 of whom underwent curettage followed by bone grafting, and 36 who had curettage followed by cementation. At the 24-month post-operative examination, significantly less degenerative change was found in patients with bone cement than in those with bone grafting. At the 50-month and later (range: 50–148 months) post-operative examination, however, no significant differences were found between the two groups, indicating that there was a significant acceleration of degenerative changes in the cemented group after the 24-month follow-up.
Literature
1.
go back to reference Bini SA, Gill K, Johnston JO (1995) Giant cell tumor of bone. Curettage and cement reconstruction. Clin Ortop 321:245–250 Bini SA, Gill K, Johnston JO (1995) Giant cell tumor of bone. Curettage and cement reconstruction. Clin Ortop 321:245–250
2.
go back to reference Blackley HR, Wunder JS, Davis AM, White LM, Kandel R, Bell RS (1999) Treatment of giant-cell tumors of long bones with curettage and bone-grafting. J Bone Jt Surg Am 81:811–820 Blackley HR, Wunder JS, Davis AM, White LM, Kandel R, Bell RS (1999) Treatment of giant-cell tumors of long bones with curettage and bone-grafting. J Bone Jt Surg Am 81:811–820
3.
go back to reference Campanacci M (1976) Giant cell tumor and chondrosarcoma. Grading, treatment and results. Cancer Res 54:257–261 Campanacci M (1976) Giant cell tumor and chondrosarcoma. Grading, treatment and results. Cancer Res 54:257–261
4.
go back to reference Campanacci M, Giunti A, Olmi R (1975) Giant-cell tumours of bone. A study of 209 cases with long term follow-up. Ital J Orthop Traumatol 1:249–277 Campanacci M, Giunti A, Olmi R (1975) Giant-cell tumours of bone. A study of 209 cases with long term follow-up. Ital J Orthop Traumatol 1:249–277
5.
go back to reference Chen TH, Su YP, Chen WM (2005) Giant cell tumors of the knee: subchondral bone integrity affects the outcome. Int Orthop 29:30–34PubMedCrossRef Chen TH, Su YP, Chen WM (2005) Giant cell tumors of the knee: subchondral bone integrity affects the outcome. Int Orthop 29:30–34PubMedCrossRef
6.
go back to reference Dreinhofer KE, Rydholm A, Bauer HC, Kreicbergs A (1995) Giant-cell tumours with fractue at diagnosis. J Bone Jt Surg Br 77:189–193 Dreinhofer KE, Rydholm A, Bauer HC, Kreicbergs A (1995) Giant-cell tumours with fractue at diagnosis. J Bone Jt Surg Br 77:189–193
7.
go back to reference Enneking WF (1987) Modification of the system for functional evaluation of surgical management of musculoskeletal tumors. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 626–639 Enneking WF (1987) Modification of the system for functional evaluation of surgical management of musculoskeletal tumors. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 626–639
8.
go back to reference Frassica FJ, Gorski JP, Pritchard DJ, Sim FH, Chao EYS (1993) A comparative analysis of subchondral replacement with polymethylmethacrylate or autologous bone graft in dogs. Clin Orthop Rel Res 293: 339–378 Frassica FJ, Gorski JP, Pritchard DJ, Sim FH, Chao EYS (1993) A comparative analysis of subchondral replacement with polymethylmethacrylate or autologous bone graft in dogs. Clin Orthop Rel Res 293: 339–378
9.
go back to reference Hisatome T, Yasunaga Y, Ikuta Y, Fujimoto Y (2002) Effects on articular cartilage of subchondral replacement with polymethylmethacrylate and calcium phosphate cement. J Biomed Mater Res 59:490–498PubMedCrossRef Hisatome T, Yasunaga Y, Ikuta Y, Fujimoto Y (2002) Effects on articular cartilage of subchondral replacement with polymethylmethacrylate and calcium phosphate cement. J Biomed Mater Res 59:490–498PubMedCrossRef
10.
go back to reference Hollinger JO, Battistone GC (1986) Biodegradable bone repair materials. Synthetic polymers and ceramics. Clin Ortop 207:290–305 Hollinger JO, Battistone GC (1986) Biodegradable bone repair materials. Synthetic polymers and ceramics. Clin Ortop 207:290–305
11.
go back to reference Hopp SG, Dahners LE, Gilbert JA (1989) A study of the mechanical strength of long bone defects treated with various autograft substitutes. An experimental investigation in the rabbit. J Orthop Res 7:579–584PubMedCrossRef Hopp SG, Dahners LE, Gilbert JA (1989) A study of the mechanical strength of long bone defects treated with various autograft substitutes. An experimental investigation in the rabbit. J Orthop Res 7:579–584PubMedCrossRef
12.
go back to reference Johnston JO (1987) Treatment of a giant cell tumor by aggressive curettage and packing with bone cement. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 512–515 Johnston JO (1987) Treatment of a giant cell tumor by aggressive curettage and packing with bone cement. In: Enneking WF (eds) Limb salvage in musculoskeletal oncology. Churchill Livingstone, New York, pp 512–515
13.
go back to reference Labs K, Perka C, Schmidt RG (2001) Treatment of stages 2 and 3 giant-cell tumor. Arch Orthop Trauma Surg 121:83–86PubMedCrossRef Labs K, Perka C, Schmidt RG (2001) Treatment of stages 2 and 3 giant-cell tumor. Arch Orthop Trauma Surg 121:83–86PubMedCrossRef
14.
go back to reference Liu HS, Wang JW (1998) Treatment of giant cell tumor of bone: a comparison of local curettage and wide resection. Chang Keng I Hsuey 21:37–43 Liu HS, Wang JW (1998) Treatment of giant cell tumor of bone: a comparison of local curettage and wide resection. Chang Keng I Hsuey 21:37–43
15.
go back to reference Malawer M, Bickels J, Meller I, Buch RG, Henshaw RM, Kollender Y (1999) Cryosurgery in the treatment of giant cell tumor. Clin Ortop 359:176–188CrossRef Malawer M, Bickels J, Meller I, Buch RG, Henshaw RM, Kollender Y (1999) Cryosurgery in the treatment of giant cell tumor. Clin Ortop 359:176–188CrossRef
16.
go back to reference McGough RL, Rutledge J, Lewis V, Lin PP, Yasko AW (2005) Impact severity of local recurrence in giant cell tumor of bone. Clin Orthop Rel Res 438:116–122 McGough RL, Rutledge J, Lewis V, Lin PP, Yasko AW (2005) Impact severity of local recurrence in giant cell tumor of bone. Clin Orthop Rel Res 438:116–122
17.
go back to reference Ozaki T, Hillmann A, Lindner N, Winkelmann W (1997) Cementation of primary aneurysmal bone cysts. Clin Orthop Rel Res 337:240–248 Ozaki T, Hillmann A, Lindner N, Winkelmann W (1997) Cementation of primary aneurysmal bone cysts. Clin Orthop Rel Res 337:240–248
18.
go back to reference Radin EL, Martin RB, Burr DB, Caterson B, Boyd RD, Goodwin C (1984) Effects of mechanical loading on the tissues of the rabbit knee. J Orthop Res 2:221–234PubMedCrossRef Radin EL, Martin RB, Burr DB, Caterson B, Boyd RD, Goodwin C (1984) Effects of mechanical loading on the tissues of the rabbit knee. J Orthop Res 2:221–234PubMedCrossRef
19.
go back to reference Radin EL, Rose RM (1986) Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 213:34–40PubMed Radin EL, Rose RM (1986) Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 213:34–40PubMed
20.
go back to reference Turcotte RE, Wunder JS, Isler MH, Bell RS, Schachar N, Masri BA, Moreau G, Davis AM (2002) Giant cell tumor of long bone: a Canadian Sarcoma Group study. Clin Orthop Rel Res 397:248–258 Turcotte RE, Wunder JS, Isler MH, Bell RS, Schachar N, Masri BA, Moreau G, Davis AM (2002) Giant cell tumor of long bone: a Canadian Sarcoma Group study. Clin Orthop Rel Res 397:248–258
21.
go back to reference Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short form health survey (SF-36). Med Care 30:473–483PubMedCrossRef Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short form health survey (SF-36). Med Care 30:473–483PubMedCrossRef
22.
go back to reference Welch RD, Berry BH, Crawford K, Zhang H, Zobitz M, Bronson D, Krishnan S (2002) Subchondral defects in caprine femora augmented with in situ setting hydroxyapatite cement, polymethylmethacrylate, or autogenous bone graft: biomechanical and histomorhological analysis after two-years. J Orthop Res 20:464–472PubMedCrossRef Welch RD, Berry BH, Crawford K, Zhang H, Zobitz M, Bronson D, Krishnan S (2002) Subchondral defects in caprine femora augmented with in situ setting hydroxyapatite cement, polymethylmethacrylate, or autogenous bone graft: biomechanical and histomorhological analysis after two-years. J Orthop Res 20:464–472PubMedCrossRef
Metadata
Title
Comparison of the degenerative changes in weight-bearing joints following cementing or grafting techniques in giant cell tumour patients: medium-term results
Authors
K. Szalay
I. Antal
J. Kiss
M. Szendroi
Publication date
01-12-2006
Publisher
Springer-Verlag
Published in
International Orthopaedics / Issue 6/2006
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-006-0190-z

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