Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Abdominal Radiology
Published in: Abdominal Radiology 2/2011

01-04-2011

Inflammatory activity in Crohn’s disease: CE-US

Authors: Vincenzo Migaleddu, Emilio Quaia, Domenico Scanu, Serra Carla, Michele Bertolotto, Girolamo Campisi, Danilo Sirigu, Giuseppe Virgilio

Published in: Abdominal Radiology | Issue 2/2011

Login to get access

Abstract

The evaluation of inflammatory activity in Crohn’s disease (CD), a crucial aspect of treatment planning and monitoring, is currently based on a sum of clinical data and imaging findings. Among the contrast enhanced cross-sectional imaging techniques (CE-US, CE-CT, CE-MR), CE-US is less invasive, more comfortable for the patient, and has significant diagnostic accuracy. In addition, it is a portable, easily repeatable, well tolerated, and ionizing radiation-free imaging modality. CE-US has been introduced as effective method in the quantitative and qualitative evaluation of CD inflammatory activity. CE-US might help in characterizing bowel-wall thickening by differentiating inflammatory neovascularisation, edema, and fibrosis. The recent chance to evaluate the bowel-wall stiffness by US elastography imaging could allow further assessment of fibrosis that characterizes the evolution of the inflammatory activity.
Literature
1.
2.
Válek V, Husty J (2009) Crohn’s disease: clinical-surgical questions and imaging answers. Eur J Radiol 69:375–380PubMedCrossRef
3.
Satsangi J, Silverberg MS, Vermiere S, et al. (2006) The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 55:749–753PubMedCrossRef
4.
Louis E, Collard A, Oger AF, et al. (2001) Behaviour of Crohn’s disease according to the Vienna classification: changing pattern over the course of the disease. Gut 49:777–782PubMedCrossRef
5.
Cosnes J, Cattan S, Blain A, et al. (2002) Long-term evolution of disease behavior of Crohn’s disease. Inflamm Bowel Dis 8(4):244–250PubMedCrossRef
6.
Henriksen M, Jahnsen J, Lygren I, et al. (2007) Clinical course of Crohn’s disease: results of a five-year population-based follow-up study (the IBSEN study). Scand J Gastroenterol 42:602–610PubMedCrossRef
7.
Helper DJ (2009) Medical management of Crohn’s disease: a guide for radiologists. Eur J Radiol 69(3):371–374 (Epub Feb 14, 2009)PubMedCrossRef
8.
Sempere GAJ, Martinez Sanjuan V, Medina Chulia E, et al. (2005) MRI evaluation of inflammatory activity in Crohn’s disease. Am J Roentgenol 184:1829–1835
9.
Maccioni F, Bruni A, Viscido A (2005) MR imaging in patients with Crohn disease: value of 2- versus T1-weighted gadolinium-enhanced MR sequences with use of an oral superparamagnetic contrast agent. Radiology 238:517–530PubMedCrossRef
10.
Bodily KD, Fletcher JG, Solem CA (2006) Crohn disease: mural attenuation and thickness at contrast-enhanced CT enterography—correlation with endoscopic and histologic findings of inflammation. Radiology 238:505–516PubMedCrossRef
11.
Solvig J, Ekberg O, Lindgren S, et al. (1995) Ultrasound examination of the small bowel: comparison with enteroclysis in patients with Crohn disease. Abdom Imaging 20:323–326PubMedCrossRef
12.
Miao YM, Koh DM, Amin Z, et al. (2002) Ultrasound and magnetic resonance imaging assessment of active bowel segments in Crohn’s disease. Clin Radiol 57:913–918PubMedCrossRef
13.
Pradel JA, David XR, Taourel P, et al. (1997) Sonographic assessment of the normal and abnormal bowel wall in nondiverticular ileitis and colitis. Abdom Imaging 2:167–172CrossRef
14.
15.
16.
Migaleddu V, Quaia E, Scano D, Virgilio G (2008) Inflammatory activity in Crohn disease: ultrasound findings. Abdom Imaging 33(5):589–597PubMedCrossRef
17.
Girlich C, Jung EM, Iesalnieks I, et al. (2009) Quantitative assessment of bowel wall vascularisation in Crohn’s disease with contrast-enhanced ultrasound and perfusion analysis. Clin Hemorheol Microcirc 43(1):141–148PubMed
18.
Adler J, Punglia D, Dillman JR, et al. (2008) CT enterography findings correlate with tissue inflammation but not fibrosis in resected small bowel Crohn’s disease. Gastroenterology 134:A195
19.
Kim K, Johnson LA, Jia C, et al. (2008) Noninvasive ultrasound elasticity imaging (UEI) of Crohn’s disease: animal model. Ultrasound Med Biol 34:902–912PubMedCrossRef
20.
Adler J, Stidham RW, Higgins PDR (2009) Bringing the inflamed and fibrotic bowel into focus: imaging in inflammatory bowel disease. Gastroenterol Hepatol 5(10)
Metadata
Title
Inflammatory activity in Crohn’s disease: CE-US
Authors
Vincenzo Migaleddu
Emilio Quaia
Domenico Scanu
Serra Carla
Michele Bertolotto
Girolamo Campisi
Danilo Sirigu
Giuseppe Virgilio
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 2/2011
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-010-9622-8

Other articles of this Issue 2/2011

Abdominal Radiology 2/2011 Go to the issue

Report

Right paraduodenal hernia: characteristic MDCT findings

Report

Appendicitis in an obturator hernia

OriginalPaper

Perinephric hematoma: semi-automated quantification of volume on MDCT: a feasibility study

OriginalPaper

Comparison of diffusion-weighted MR imaging and multidetector-row CT in the detection of liver metastases in patients operated for pancreatic cancer

OriginalPaper

Acute gastrointestinal bleeding: CT angiography with multi-planar reformatting

OriginalPaper

Petersen’s hernia as a complication of bariatric surgery: CT findings
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Image Credits