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Published in: European Journal of Nuclear Medicine and Molecular Imaging 5/2021

Open Access 01-05-2021 | Prostate Cancer | Guidelines

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Authors: Francesco Ceci, Daniela E. Oprea-Lager, Louise Emmett, Judit A. Adam, Jamshed Bomanji, Johannes Czernin, Matthias Eiber, Uwe Haberkorn, Michael S. Hofman, Thomas A. Hope, Rakesh Kumar, Steven P. Rowe, Sarah M. Schwarzenboeck, Stefano Fanti, Ken Herrmann

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 5/2021

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Abstract

Rationale

The development of consensus guidelines for interpretation of Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is needed to provide more consistent reports in clinical practice. The standardization of PSMA-PET interpretation may also contribute to increasing the data reproducibility within clinical trials. Finally, guidelines in PSMA-PET interpretation are needed to communicate the exact location of findings to referring physicians, to support clinician therapeutic management decisions.

Methods

A panel of worldwide experts in PSMA-PET was established. Panelists were selected based on their expertise and publication record in the diagnosis or treatment of PCa, in their involvement in clinical guidelines and according to their expertise in the clinical application of radiolabeled PSMA inhibitors. Panelists were actively involved in all stages of a modified, nonanonymous, Delphi consensus process.

Results

According to the findings obtained by modified Delphi consensus process, panelist recommendations were implemented in a structured report for PSMA-PET.

Conclusions

The E-PSMA standardized reporting guidelines, a document supported by the European Association of Nuclear Medicine (EANM), provide consensus statements among a panel of experts in PSMA-PET imaging, to develop a structured report for PSMA-PET in prostate cancer and to harmonize diagnostic interpretation criteria.
Appendix
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Metadata
Title
E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET
Authors
Francesco Ceci
Daniela E. Oprea-Lager
Louise Emmett
Judit A. Adam
Jamshed Bomanji
Johannes Czernin
Matthias Eiber
Uwe Haberkorn
Michael S. Hofman
Thomas A. Hope
Rakesh Kumar
Steven P. Rowe
Sarah M. Schwarzenboeck
Stefano Fanti
Ken Herrmann
Publication date
01-05-2021
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 5/2021
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-021-05245-y

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