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European Journal of Nuclear Medicine and Molecular Imaging

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01-10-2004 | Editorial

Role of MIBG myocardial scintigraphy in the assessment of heart failure: the need to establish evidence

Authors: Shohei Yamashina, Jun-ichi Yamazaki

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 10/2004

Excerpt

Recently, it has become apparent that the morbidity and mortality of heart failure are likely to show an upward trend, which represents a major medical challenge. The sympathetic nervous system and the renin-angiotensin system play a crucial role in the pathophysiology of heart failure. If cardiac function deteriorates, sympathetic nerve activity accelerates to compensate for the loss of function and works to maintain cardiac output. However, it has become clear that an increase in myocardial oxygen consumption and factors such as apoptosis, inflammatory cytokines, oxidative stress and ventricular remodelling may result in exacerbation of heart failure if excessive stress on the sympathetic nerve is prolonged. …

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Title: Role of MIBG myocardial scintigraphy in the assessment of heart failure: the need to establish evidence
Authors: Shohei Yamashina
Jun-ichi Yamazaki
Publication date: 01-10-2004
Publisher: Springer-Verlag
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 10/2004
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-004-1493-1

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Role of MIBG myocardial scintigraphy in the assessment of heart failure: the need to establish evidence

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