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Skeletal Radiology
Published in: Skeletal Radiology 12/2021

Open Access 01-12-2021 | Magnetic Resonance Imaging | Review Article

MRI nomenclature for musculoskeletal infection

Authors: Erin F. Alaia, Avneesh Chhabra, Claus S. Simpfendorfer, Micah Cohen, Douglas N. Mintz, Josephina A. Vossen, Adam C. Zoga, Jan Fritz, Charles E. Spritzer, David G. Armstrong, William B. Morrison

Published in: Skeletal Radiology | Issue 12/2021

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Abstract

The Society of Skeletal Radiology (SSR) Practice Guidelines and Technical Standards Committee identified musculoskeletal infection as a White Paper topic, and selected a Committee, tasked with developing a consensus on nomenclature for MRI of musculoskeletal infection outside the spine. The objective of the White Paper was to critically assess the literature and propose standardized terminology for imaging findings of infection on MRI, in order to improve both communication with clinical colleagues and patient care.
A definition was proposed for each term; debate followed, and the committee reached consensus. Potential controversies were raised, with formulated recommendations. The committee arrived at consensus definitions for cellulitis, soft tissue abscess, and necrotizing infection, while discouraging the nonspecific term phlegmon. For bone infection, the term osteitis is not useful; the panel recommends using terms that describe the likelihood of osteomyelitis in cases where definitive signal changes are lacking. The work was presented virtually to SSR members, who had the opportunity for review and modification prior to submission for publication.
Literature
1.
Duryea D, Bernard S, Flemming D, Walker E, French C. Outcomes in diabetic foot ulcer patients with isolated T2 marrow signal abnormality in the underlying bone: should the diagnosis of “osteitis” be changed to “early osteomyelitis”? Skeletal Radiol. 2017;46(10):1327–33.PubMedCrossRef
2.
Hirschfeld CB, Kapadia SN, Bryan J, Jannat-Khah DP, May B, Vielemeyer O, et al. Impact of diagnostic bone biopsies on the management of non-vertebral osteomyelitis: a retrospective cohort study. Medicine (Baltimore). 2019;98(34):e16954.CrossRef
3.
Hoang D, Fisher S, Oz OK, La Fontaine J, Chhabra A. Percutaneous CT guided bone biopsy for suspected osteomyelitis: diagnostic yield and impact on patient’s treatment change and recovery. Eur J Radiol. 2019;114:85–91.PubMedCrossRef
4.
Lipsky BA, Berendt AR, Cornia PB, Pile JC, Peters EJ, Armstrong DG, et al. 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. Clin Infect Dis. 2012;54(12):e132-173.PubMedCrossRef
5.
American College of Radiology, ACR Manual on Contrast Media. 2021.
6.
7.
Hayeri MR, Ziai P, Shehata ML, Teytelboym OM, Huang BK. Soft-tissue infections and their imaging mimics from cellulitis to necrotizing fasciitis. 2016;36(6):1888–910.
8.
Kirchgesner T, Tamigneaux C, Acid S, Perlepe V, Lecouvet F, Malghem J, et al. Fasciae of the musculoskeletal system: MRI findings in trauma, infection and neoplastic diseases. Insights Imaging. 2019;10(1):47.PubMedPubMedCentralCrossRef
9.
Brook I. Microbiology and management of soft tissue and muscle infections. Int J Surg. 2008;6(4):328–38.PubMedCrossRef
10.
11.
Palestro CJ, Love C, Miller TT. Infection and musculoskeletal conditions: imaging of musculoskeletal infections. Best Pract Res Clin Rheumatol. 2006;20(6):1197–218.PubMedCrossRef
12.
13.
Cook TA, Rahim N, Simpson HC, Galland RB. Magnetic resonance imaging in the management of diabetic foot infection. Br J Surg. 1996;83(2):245–8.PubMed
14.
Rahmouni A, Chosidow O, Mathieu D, Gueorguieva E, Jazaerli N, Radier C, et al. MR imaging in acute infectious cellulitis. Radiology. 1994;192(2):493–6.PubMedCrossRef
15.
Schmid MR, Kossmann T, Duewell S. Differentiation of necrotizing fasciitis and cellulitis using MR imaging. AJR Am J Roentgenol. 1998;170(3):615–20.PubMedCrossRef
16.
Ledermann HP, Morrison WB, Schweitzer ME. Pedal abscesses in patients suspected of having pedal osteomyelitis: analysis with MR imaging. Radiology. 2002;224(3):649–55.PubMedCrossRef
17.
Kan JH, Young RS, Yu C, Hernanz-Schulman M. Clinical impact of gadolinium in the MRI diagnosis of musculoskeletal infection in children. Pediatr Radiol. 2010;40(7):1197–205.PubMedCrossRef
18.
Saiag P, Le Breton C, Pavlovic M, Fouchard N, Delzant G, Bigot JM. Magnetic resonance imaging in adults presenting with severe acute infectious cellulitis. Arch Dermatol. 1994;130(9):1150–8.PubMedCrossRef
19.
Hopkins KL, Li KC, Bergman G. Gadolinium-DTPA-enhanced magnetic resonance imaging of musculoskeletal infectious processes. Skeletal Radiol. 1995;24(5):325–30.PubMedCrossRef
20.
Ledermann HP, Schweitzer ME, Morrison WB. Nonenhancing tissue on MR imaging of pedal infection: characterization of necrotic tissue and associated limitations for diagnosis of osteomyelitis and abscess. AJR Am J Roentgenol. 2002;178(1):215–22.PubMedCrossRef
21.
Lipsky BA, Aragon-Sanchez J, Diggle M, Embil J, Kono S, Lavery L, et al. IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes. Diabetes Metab Res Rev. 2016;32(Suppl 1):45–74.PubMedCrossRef
22.
Spichler A, Hurwitz BL, Armstrong DG, Lipsky BA. Microbiology of diabetic foot infections: from Louis Pasteur to “crime scene investigation.” BMC Med. 2015;13:2.PubMedPubMedCentralCrossRef
23.
Horowitz JD, Durham JR, Nease DB, Lukens ML, Wright JG, Smead WL. Prospective evaluation of magnetic resonance imaging in the management of acute diabetic foot infections. Ann Vasc Surg. 1993;7(1):44–50.PubMedCrossRef
24.
Durham JR, Lukens ML, Campanini DS, Wright JG, Smead WL. Impact of magnetic resonance imaging on the management of diabetic foot infections. Am J Surg. 1991;162(2):150–3 discussion 153-154.PubMedCrossRef
25.
Donovan A, Schweitzer ME. Use of MR imaging in diagnosing diabetes-related pedal osteomyelitis. Radiographics. 2010;30(3):723–36.PubMedCrossRef
26.
Kaim ALH, Bongartz G, Messmer P, Muller-Brand J, Steinbrich W. Chronic post-traumatic osteomyelitis of the lower extremity: comparison of magnetic resonance imaging and combined bone scintigraphy/immunoscintigraphy with radiolabelled monoclonal antigranulocyte antibodies. Skeletal Radiol. 2000;29:378–86.PubMedCrossRef
27.
Gage HC WE. The radiological exploration of sinus tracts, fistulae, and infected cavities. Radiology 1943:233–248.
28.
Morrison WB, Schweitzer ME, Batte WG, Radack DP, Russel KM. Osteomyelitis of the foot: relative importance of primary and secondary MR imaging signs. Radiology. 1998;207(3):625–32.PubMedCrossRef
29.
Morrison WB, Schweitzer ME, Bock GW, Mitchell DG, Hume EL, Pathria MN, et al. Diagnosis of osteomyelitis: utility of fat-suppressed contrast-enhanced MR imaging. Radiology. 1993;189(1):251–7.PubMedCrossRef
30.
Sonin AH, Resnik CS, Mulligan ME, Murphey MD. General case of the day Squamous cell carcinoma arising in a chronic draining sinus tract as a complication of chronic osteomyelitis. Radiographics. 1998;18(2):530–2.PubMedCrossRef
31.
Manaster B.J. MD, Disler D. Musculoskeletal imaging: the requisites. 4th edn: Elsevier, 2013.
32.
Chandnani VP, Beltran J, Morris CS, Khalil SN, Mueller CF, Burk JM, et al. Acute experimental osteomyelitis and abscesses: detection with MR imaging versus CT. Radiology. 1990;174(1):233–6.PubMedCrossRef
33.
Beltran J, Noto AM, McGhee RB, Freedy RM, McCalla MS. Infections of the musculoskeletal system: high-field-strength MR imaging. Radiology. 1987;164(2):449–54.PubMedCrossRef
34.
Averill LW, Hernandez A, Gonzalez L, Pena AH, Jaramillo D. Diagnosis of osteomyelitis in children: utility of fat-suppressed contrast-enhanced MRI. AJR Am J Roentgenol. 2009;192(5):1232–8.PubMedCrossRef
35.
McGuinness B, Wilson N, Doyle AJ. The “penumbra sign” on T1-weighted MRI for differentiating musculoskeletal infection from tumour. Skeletal Radiol. 2007;36(5):417–21.PubMedCrossRef
36.
Marti-Bonmati L, Aparisi F, Poyatos C, Vilar J. Brodie abscess: MR imaging appearance in 10 patients. J Magn Reson Imaging. 1993;3(3):543–6.PubMedCrossRef
37.
Miller TT, Randolph DA Jr, Staron RB, Feldman F, Cushin S. Fat-suppressed MRI of musculoskeletal infection: fast T2-weighted techniques versus gadolinium-enhanced T1-weighted images. Skeletal Radiol. 1997;26(11):654–8.PubMedCrossRef
38.
Paajanen H, Grodd W, Revel D, Engelstad B, Brasch RC. Gadolinium-DTPA enhanced MR imaging of intramuscular abscesses. Magn Reson Imaging. 1987;5(2):109–15.PubMedCrossRef
39.
Kumar Y, Khaleel M, Boothe E, Awdeh H, Wadhwa V, Chhabra A. Role of diffusion weighted imaging in musculoskeletal infections: current perspectives. Eur Radiol. 2017;27(1):414–23.PubMedCrossRef
40.
Yu CW, Hsiao JK, Hsu CY, Shih TT. Bacterial pyomyositis: MRI and clinical correlation. Magn Reson Imaging. 2004;22(9):1233–41.PubMedCrossRef
41.
Sanghvi DA, Iyer VR, Deshmukh T, Hoskote SS. MRI features of tuberculosis of the knee. Skeletal Radiol. 2009;38(3):267–73.PubMedCrossRef
42.
Savarese LG, Monsignore LM, de Andrade HM, Martinez R, Nogueira-Barbosa MH. Magnetic resonance imaging findings of paracoccidioidomycosis in the musculoskeletal system. Trop Med Int Health. 2015;20(10):1346–54.PubMedCrossRef
43.
Gordon BA, Martinez S, Collins AJ. Pyomyositis: characteristics at CT and MR imaging. Radiology. 1995;197(1):279–86.PubMedCrossRef
44.
Soler R, Rodriguez E, Aguilera C, Fernandez R. Magnetic resonance imaging of pyomyositis in 43 cases. Eur J Radiol. 2000;35(1):59–64.PubMedCrossRef
45.
Dariushnia SR, Mitchell JW, Chaudry G, Hogan MJ. Society of interventional radiology quality improvement standards for image-guided percutaneous drainage and aspiration of abscesses and fluid collections. J Vasc Interv Radiol. 2020;31(4):662–6 e664.PubMedCrossRef
46.
Chun CW, Jung JY, Baik JS, Jee WH, Kim SK, Shin SH. Detection of soft-tissue abscess: Comparison of diffusion-weighted imaging to contrast-enhanced MRI. J Magn Reson Imaging. 2018;47(1):60–8.PubMedCrossRef
47.
Fan ST, Choi TK, Chan FL, Lai EC, Wong J. Pancreatic phlegmon: what is it? Am J Surg. 1989;157(6):544–7.PubMedCrossRef
48.
Zaheer A, Singh VK, Qureshi RO, Fishman EK. The revised Atlanta classification for acute pancreatitis: updates in imaging terminology and guidelines. Abdom Imaging. 2013;38(1):125–36.PubMedCrossRef
49.
Palmer WBL, Bonar F, Choi J, Cotten A, Griffith JF, Robinson P, Pfirrmann CW. Glossary of terms for musculoskeletal radiology. Skeletal Radiol. 2020;49(Suppl 1):1–33.PubMedPubMedCentralCrossRef
50.
Soldatos T, Durand DJ, Subhawong TK, Carrino JA, Chhabra A. Magnetic resonance imaging of musculoskeletal infections: systematic diagnostic assessment and key points. Acad Radiol. 2012;19(11):1434–43.PubMedCrossRef
51.
Wilcox JR, Carter MJ, Covington S. Frequency of debridements and time to heal: a retrospective cohort study of 312 744 wounds. JAMA Dermatol. 2013;149(9):1050–8.PubMedCrossRef
52.
Armstrong DG, Lavery LA, Nixon BP, Boulton AJ. It’s not what you put on, but what you take off: techniques for debriding and off-loading the diabetic foot wound. Clin Infect Dis. 2004;39(Suppl 2):S92-99.PubMedCrossRef
53.
Goh TGL, Ang CH, Wong CH. Early diagnosis of necrotizing fasciitis. Br J Surg. 2014;101(1):119–25.CrossRef
54.
Wong CH, Khin LW, Heng KS, Tan KC, Low CO. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Crit Care Med. 2004;32(7):1535–41.PubMedCrossRef
55.
Kim KT, Kim YJ, Won Lee J, Kim YJ, Park SW, Lim MK, et al. Can necrotizing infectious fasciitis be differentiated from nonnecrotizing infectious fasciitis with MR imaging? Radiology. 2011;259(3):816–24.PubMedCrossRef
56.
Wysoki MG, Santora TA, Shah RM, Friedman AC. Necrotizing fasciitis: CT characteristics. Radiology. 1997;203(3):859–63.PubMedCrossRef
57.
Loh NN, Ch’en IY, Cheung LP, Li KC. Deep fascial hyperintensity in soft-tissue abnormalities as revealed by T2-weighted MR imaging. AJR Am J Roentgenol. 1997;168(5):1301–4.PubMedCrossRef
58.
Brothers TE, Tagge DU, Stutley JE, Conway WF, Del Schutte H, Jr., Byrne TK. . Magnetic resonance imaging differentiates between necrotizing and non-necrotizing fasciitis of the lower extremity. J Am Coll Surg. 1998;187(4):416–21.PubMedCrossRef
59.
Yoon MA, Chung HW, Yeo Y, Yoo HJ, Kang Y, Chee CG, et al. Distinguishing necrotizing from non-necrotizing fasciitis: a new predictive scoring integrating MRI in the LRINEC score. Eur Radiol. 2019;29(7):3414–23.PubMedCrossRef
60.
Anaya DA, Dellinger EP. Necrotizing soft-tissue infection: diagnosis and management. Clin Infect Dis. 2007;44(5):705–10.PubMedCrossRef
61.
Seok JH, Jee WH, Chun KA, Kim JY, Jung CK, Kim YR, et al. Necrotizing fasciitis versus pyomyositis: discrimination with using MR imaging. Korean J Radiol. 2009;10(2):121–8.PubMedPubMedCentralCrossRef
62.
Resnick D. Diagnosis of bone and joint disorders. 4th ed. Philadephia: W.B. Saunders Company; 2002.
63.
64.
Mandell D. and Bennett’s principles and practice of infectious diseases. 8th ed. Philadelphia, PA: Saunders; 2015.
65.
Karchevsky M, Schweitzer ME, Morrison WB, Parellada JA. MRI findings of septic arthritis and associated osteomyelitis in adults. AJR Am J Roentgenol. 2004;182(1):119–22.PubMedCrossRef
66.
Monsalve J, Kan JH, Schallert EK, Bisset GS, Zhang W, Rosenfeld SB. Septic arthritis in children: frequency of coexisting unsuspected osteomyelitis and implications on imaging work-up and management. AJR Am J Roentgenol. 2015;204(6):1289–95.PubMedCrossRef
67.
Schallert EK, Kan JH, Monsalve J, Zhang W, Bisset GS 3rd, Rosenfeld S. Metaphyseal osteomyelitis in children: how often does MRI-documented joint effusion or epiphyseal extension of edema indicate coexisting septic arthritis? Pediatr Radiol. 2015;45(8):1174–81.PubMedCrossRef
68.
Hermet M, Minichiello E, Flipo RM, Dubost JJ, Allanore Y, Ziza JM, et al. Infectious sacroiliitis: a retrospective, multicentre study of 39 adults. BMC Infect Dis. 2012;12:305.PubMedPubMedCentralCrossRef
69.
Bierry G, Huang AJ, Chang CY, Torriani M, Bredella MA. MRI findings of treated bacterial septic arthritis. Skeletal Radiol. 2012;41(12):1509–16.PubMedCrossRef
70.
Kim EY, Kwack KS, Cho JH, Lee DH, Yoon SH. Usefulness of dynamic contrast-enhanced MRI in differentiating between septic arthritis and transient synovitis in the hip joint. AJR Am J Roentgenol. 2012;198(2):428–33.PubMedCrossRef
71.
Sturzenbecher A, Braun J, Paris S, Biedermann T, Hamm B, Bollow M. MR imaging of septic sacroiliitis. Skeletal Radiol. 2000;29(8):439–46.PubMedCrossRef
72.
Graif M, Schweitzer ME, Deely D, Matteucci T. The septic versus nonseptic inflamed joint: MRI characteristics. Skeletal Radiol. 1999;28(11):616–20.PubMedCrossRef
73.
Kanna RM, Bosco A, Shetty AP, Rajasekaran S. Unilateral sacroiliitis: differentiating infective and inflammatory etiology by magnetic resonance imaging and tissue studies. Eur Spine J. 2019;28(4):762–7.PubMedCrossRef
74.
Prakash M, Gupta P, Sen RK, Sharma A, Khandelwal N. Magnetic resonance imaging evaluation of tubercular arthritis of the ankle and foot. Acta Radiol. 2015;56(10):1236–41.PubMedCrossRef
75.
Reinus WR, De Cotiis D, Schaffer A. Changing patterns of septic tenosynovitis of the distal extremities. Emerg Radiol. 2015;22(2):133–9.PubMedCrossRef
76.
Jaovisidha S, Chen C, Ryu KN, Siriwongpairat P, Pekanan P, Sartoris DJ, et al. Tuberculous tenosynovitis and bursitis: imaging findings in 21 cases. Radiology. 1996;201(2):507–13.PubMedCrossRef
77.
Ledermann HP, Morrison WB, Schweitzer ME, Raikin SM. Tendon involvement in pedal infection: MR analysis of frequency, distribution, and spread of infection. AJR Am J Roentgenol. 2002;179(4):939–47.PubMedCrossRef
78.
Floemer F, Morrison WB, Bongartz G, Ledermann HP. MRI characteristics of olecranon bursitis. AJR Am J Roentgenol. 2004;183(1):29–34.PubMedCrossRef
79.
Edeiken J, Hodes PJ, Caplan LH. New bone production and periosteal reaction. Am J Roentgenol Radium Ther Nucl Med. 1966;97(3):708–18.PubMedCrossRef
80.
Ogden JA. Pediatric osteomyelitis and septic arthritis: the pathology of neonatal disease. Yale J Biol Med. 1979;52(5):423–48.PubMedPubMedCentral
81.
Trueta J. The 3 types of acute hematogenous osteomyelitis. Schweiz Med Wochenschr. 1963;93:306–12.PubMed
82.
Wang T, Zhang X, Bikle DD. Osteogenic differentiation of periosteal cells during fracture healing. J Cell Physiol. 2017;232(5):913–21.PubMedCrossRef
83.
McCarville MB, Chen JY, Coleman JL, Li Y, Li X, Adderson EE, et al. Distinguishing osteomyelitis from Ewing sarcoma on radiography and MRI. AJR Am J Roentgenol. 2015;205(3):640–50 quiz 651.PubMedPubMedCentralCrossRef
84.
Weenders SG, Janssen NE, Landman GW, van den Berg FP. Subperiosteal abscess in a child. Trueta's osteomyelitis hypothesis undermined? Orthop Traumatol Surg Res. 2015; 101(6):763–765.
85.
Belthur MV, Birchansky SB, Verdugo AA, Mason EO Jr, Hulten KG, Kaplan SL, et al. Pathologic fractures in children with acute Staphylococcus aureus osteomyelitis. J Bone Joint Surg Am. 2012;94(1):34–42.PubMedCrossRef
86.
Labbe JL, Peres O, Leclair O, Goulon R, Scemama P, Jourdel F, et al. Acute osteomyelitis in children: the pathogenesis revisited? Orthop Traumatol Surg Res. 2010;96(3):268–75.PubMedCrossRef
87.
Wyers MR, Samet JD, Mithal LB. Physeal separation in pediatric osteomyelitis. Pediatr Radiol. 2019;49(9):1229–33.PubMedCrossRef
88.
Jaramillo D, Dormans JP, Delgado J, Laor T, St Geme JW, 3rd. . Hematogenous osteomyelitis in infants and children: imaging of a changing disease. Radiology. 2017;283(3):629–43.PubMedCrossRef
89.
Ware JK, Browner BD, Pesanti EL. Chapter 24: chronic osteomyelitis. Skeletal trauma: basic science, management, and reconstruction 5th ed. Philadelphia: Saunders. p.609–635.
90.
Ostergaard M, Peterfy C, Conaghan P, McQueen F, Bird P, Ejbjerg B, et al. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies Core set of MRI acquisitions joint pathology definitions and the OMERACT RA-MRI scoring system. J Rheumatol. 2003;30(6):1385–6.PubMed
91.
Ledermann HP, Morrison WB, Schweitzer ME. MR image analysis of pedal osteomyelitis: distribution, patterns of spread, and frequency of associated ulceration and septic arthritis. Radiology. 2002;223(3):747–55.PubMedCrossRef
92.
Lipsky BA, Weigelt JA, Sun X, Johannes RS, Derby KG, Tabak YP. Developing and validating a risk score for lower-extremity amputation in patients hospitalized for a diabetic foot infection. Diabetes Care. 2011;34(8):1695–700.PubMedPubMedCentralCrossRef
93.
Grayson ML, Gibbons GW, Balogh K, Levin E, Karchmer AW. Probing to bone in infected pedal ulcers A clinical sign of underlying osteomyelitis in diabetic patients. JAMA. 1995;273(9):721–3.PubMedCrossRef
94.
Butalia S, Palda VA, Sargeant RJ, Detsky AS, Mourad O. Does this patient with diabetes have osteomyelitis of the lower extremity? JAMA. 2008;299(7):806–13.PubMedCrossRef
95.
Kapoor A, Page S, Lavalley M, Gale DR, Felson DT. Magnetic resonance imaging for diagnosing foot osteomyelitis: a meta-analysis. Arch Intern Med. 2007;167(2):125–32.PubMedCrossRef
96.
Dinh MT, Abad CL, Safdar N. Diagnostic accuracy of the physical examination and imaging tests for osteomyelitis underlying diabetic foot ulcers: meta-analysis. Clin Infect Dis. 2008;47(4):519–27.PubMedCrossRef
97.
Erdman WA, Tamburro F, Jayson HT, Weatherall PT, Ferry KB, Peshock RM. Osteomyelitis: characteristics and pitfalls of diagnosis with MR imaging. Radiology. 1991;180(2):533–9.PubMedCrossRef
98.
Collins MS, Schaar MM, Wenger DE, Mandrekar JN. T1-weighted MRI characteristics of pedal osteomyelitis. AJR Am J Roentgenol. 2005;185(2):386–93.PubMedCrossRef
99.
Howe BM, Wenger DE, Mandrekar J, Collins MS. T1-weighted MRI imaging features of pathologically proven non-pedal osteomyelitis. Acad Radiol. 2013;20(1):108–14.PubMedCrossRef
100.
Sax AJ, Halpern EJ, Zoga AC, Roedl JB, Belair JA, Morrison WB. Predicting osteomyelitis in patients whose initial MRI demonstrated bone marrow edema without corresponding T1 signal marrow replacement. Skeletal Radiol. 2020;49(8):1239–47.PubMedCrossRef
101.
Grey AC, Davies AM, Mangham DC, Grimer RJ, Ritchie DA. The “penumbra sign” on T1-weighted MR imaging in subacute osteomyelitis: frequency, cause and significance. Clin Radiol. 1998;53(8):587–92.PubMedCrossRef
102.
Dangman BC, Hoffer FA, Rand FF, O’Rourke EJ. Osteomyelitis in children: gadolinium-enhanced MR imaging. Radiology. 1992;182(3):743–7.PubMedCrossRef
103.
Ahmadi ME, Morrison WB, Carrino JA, Schweitzer ME, Raikin SM, Ledermann HP. Neuropathic arthropathy of the foot with and without superimposed osteomyelitis: MR imaging characteristics. Radiology. 2006;238(2):622–31.PubMedCrossRef
104.
Delgado J, Bedoya MA, Green AM, Jaramillo D, Ho-Fung V. Utility of unenhanced fat-suppressed T1-weighted MRI in children with sickle cell disease – can it differentiate bone infarcts from acute osteomyelitis? Pediatr Radiol. 2015;45(13):1981–7.PubMedCrossRef
105.
Bogoch E, Thompson G, Salter RB. Foci of chronic circumscribed osteomyelitis (Brodie’s abscess) that traverse the epiphyseal plate. J Pediatr Orthop. 1984;4(2):162–9.PubMedCrossRef
106.
107.
Maffulli N, Papalia R, Zampogna B, Torre G, Albo E, Denaro V. The management of osteomyelitis in the adult. Surgeon. 2016;14(6):345–60.PubMedCrossRef
108.
Diagnosis and management of bone infections. Jauregui LE, editor. New York, M. Dekker, 1995.
109.
Mandell JC, Khurana B, Smith JT, Czuczman GJ, Ghazikhanian V, Smith SE. Osteomyelitis of the lower extremity: pathophysiology, imaging, and classification, with an emphasis on diabetic foot infection. Emerg Radiol. 2018;25(2):175–88.PubMedCrossRef
110.
Pineda C, Vargas A, Rodriguez AV. Imaging of osteomyelitis: current concepts. Infect Dis Clin North Am. 2006;20(4):789–825.PubMedCrossRef
111.
Jennin F, Bousson V, Parlier C, Jomaah N, Khanine V, Laredo JD. Bony sequestrum: a radiologic review. Skeletal Radiol. 2011;40(8):963–75.PubMedCrossRef
112.
Dorland’s illustrated medical dictionary 25th edn. Friel, JP, editor. Philadelphia, London, Toronto. W.B. Saunders, 1974.
113.
Madsen JL. Bone SPECT/CT detection of a sequestrum in chronic-infected nonunion of the tibia. Clin Nucl Med. 2008;33(10):700–1.PubMedCrossRef
114.
Lankinen P, Seppanen M, Mattila K, Kallajoki M, Knuuti J, Aro HT. Intensity of (18)F-FDG PET uptake in culture-negative and culture-positive cases of chronic osteomyelitis. Contrast Media Mol Imaging. 2017;2017:9754293.PubMedPubMedCentralCrossRef
115.
Brady RA, Leid JG, Calhoun JH, Costerton JW, Shirtliff ME. Osteomyelitis and the role of biofilms in chronic infection. FEMS Immunol Med Microbiol. 2008;52(1):13–22.PubMedCrossRef
116.
Capitanio MA, Kirkpatrick JA. Early roentgen observations in acute osteomyelitis. Am J Roentgenol Radium Ther Nucl Med. 1970;108(3):488–96.PubMedCrossRef
117.
Bonakdar-pour A, Gaines VD. The radiology of osteomyelitis. Orthop Clin North Am. 1983;14(1):21–37.PubMedCrossRef
118.
Azouz EM. Computed tomography in bone and joint infections. J Can Assoc Radiol. 1981;32(2):102–6.PubMed
119.
Davies AM, Grimer R. The penumbra sign in subacute osteomyelitis. Eur Radiol. 2005;15(6):1268–70.PubMedCrossRef
120.
Unger E, Moldofsky P, Gatenby R, Hartz W, Broder G. Diagnosis of osteomyelitis by MR imaging. AJR Am J Roentgenol. 1988;150(3):605–10.PubMedCrossRef
Metadata
Title
MRI nomenclature for musculoskeletal infection
Authors
Erin F. Alaia
Avneesh Chhabra
Claus S. Simpfendorfer
Micah Cohen
Douglas N. Mintz
Josephina A. Vossen
Adam C. Zoga
Jan Fritz
Charles E. Spritzer
David G. Armstrong
William B. Morrison
Publication date
01-12-2021
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 12/2021
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-021-03807-7

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