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Skeletal Radiology
Published in: Skeletal Radiology 12/2007

01-12-2007 | Case Report

Multifocal peripheral nerve involvement associated with multiple myeloma

Authors: Yoshikazu Okamoto, Manabu Minami, Eriko Tohno, Izumi Anno, Akira Kunimatshu, Takuya Ueda

Published in: Skeletal Radiology | Issue 12/2007

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Abstract

Infiltration of myeloma cells along the peripheral nerve is extremely rare, while multiple myeloma occasionally infiltrates the central nervous system. We present details of a patient in whom multiple myeloma had infiltrated a branch of the femoral nerve of the right inguinal region as well as the left ulnar nerve. The infiltration formed soft tissue masses, with the thickened nerves shown to be penetrating the center of the masses on ultrasonography and magnetic resonance imaging.
Literature
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Pontikoglou C, Fragos C, Kolyvaki E, Samonis G, Eliopoulos GD, Papadaki HA. Multiple myeloma involving the central nervous system: a report of two cases with unusual manifestations. Leuk Lymphoma 2005; 46: 737–741.PubMedCrossRef
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Stuart JE, Smith AC. Plasmacytoma of the superficial radial nerve. J Hand Surg [Am] 2001; 26: 776–780.CrossRef
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Denier C, Lozeron P, Adams D, et al. Multifocal neuropathy due to plasma cell infiltration of peripheral nerves in multiple myeloma. Neurology 2006; 66: 917–918.PubMedCrossRef
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Johnson BA, Fram EK, Johnson PC, Jacobowitz R. The variable MR appearance of primary lymphoma of the central nervous system: comparison with histopathologic features. AJNR Am J Neuroradiol 1997; 18: 563–572.PubMed
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Laurin S, Akerman M, Kindblom LG, Gunterberg B. Angiography in myeloma (plasmacytoma). A correlated angiographic and histologic study. Skeletal Radiol 1979; 4: 8–18.PubMedCrossRef
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Metadata
Title
Multifocal peripheral nerve involvement associated with multiple myeloma
Authors
Yoshikazu Okamoto
Manabu Minami
Eriko Tohno
Izumi Anno
Akira Kunimatshu
Takuya Ueda
Publication date
01-12-2007
Publisher
Springer-Verlag
Published in
Skeletal Radiology / Issue 12/2007
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-007-0353-z

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