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Open Access 01-07-2007 | Review Article

The spine in Paget’s disease

Authors: C. Dell’Atti, V. N. Cassar-Pullicino, R. K. Lalam, B. J. Tins, P. N. M. Tyrrell

Published in: Skeletal Radiology | Issue 7/2007

Abstract

Paget’s disease (PD) is a chronic metabolically active bone disease, characterized by a disturbance in bone modelling and remodelling due to an increase in osteoblastic and osteoclastic activity. The vertebra is the second most commonly affected site. This article reviews the various spinal pathomechanisms and osseous dynamics involved in producing the varied imaging appearances and their clinical relevance. Advanced imaging of osseous, articular and bone marrow manifestations of PD in all the vertebral components are presented. Pagetic changes often result in clinical symptoms including back pain, spinal stenosis and neural dysfunction. Various pathological complications due to PD involvement result in these clinical symptoms. Recognition of the imaging manifestations of spinal PD and the potential complications that cause the clinical symptoms enables accurate assessment of patients prior to appropriate management.

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Title: The spine in Paget’s disease
Authors: C. Dell’Atti
V. N. Cassar-Pullicino
R. K. Lalam
B. J. Tins
P. N. M. Tyrrell
Publication date: 01-07-2007
Publisher: Springer-Verlag
Published in: Skeletal Radiology / Issue 7/2007
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-006-0270-6

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The spine in Paget’s disease

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