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01-12-2015 | Original Article

Development and validation of an ultrasound scoring system for children with suspected acute appendicitis

Authors: Sara C. Fallon, Robert C. Orth, R. Paul Guillerman, Martha M. Munden, Wei Zhang, Simone C. Elder, Andrea T. Cruz, Mary L. Brandt, Monica E. Lopez, George S. Bisset

Published in: Pediatric Radiology | Issue 13/2015

Abstract

Background

To facilitate consistent, reliable communication among providers, we developed a scoring system (Appy-Score) for reporting limited right lower quadrant ultrasound (US) exams performed for suspected pediatric appendicitis.

Objective

The purpose of this study was to evaluate implementation of this scoring system and its ability to risk-stratify children with suspected appendicitis.

Materials and methods

In this HIPAA compliant, Institutional Review Board-approved study, the Appy-Score was applied retrospectively to all limited abdominal US exams ordered for suspected pediatric appendicitis through our emergency department during a 5-month pre-implementation period (Jan 1, 2013, to May 31, 2013), and Appy-Score use was tracked prospectively post-implementation (July 1, 2013, to Sept. 30,2013). Appy-Score strata were: 1 = normal completely visualized appendix; 2 = normal partially visualized appendix; 3 = non-visualized appendix, 4 = equivocal, 5a = non-perforated appendicitis and 5b = perforated appendicitis. Appy-Score use, frequency of appendicitis by Appy-Score stratum, and diagnostic performance measures of US exams were computed using operative and clinical finding as reference standards. Secondary outcome measures included rates of CT imaging following US exams and negative appendectomy rates.

Results

We identified 1,235 patients in the pre-implementation and 686 patients in the post-implementation groups. Appy-Score use increased from 24% (37/155) in July to 89% (226/254) in September (P < 0.001). Appendicitis frequency by Appy-Score stratum post-implementation was: 1 = 0.5%, 2 = 0%, 3 = 9.5%, 4 = 44%, 5a = 92.3%, and 5b = 100%. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 96.3% (287/298), 93.9% (880/937), 83.4% (287/344), and 98.8% (880/891) pre-implementation and 93.0% (200/215), 92.6% (436/471), 85.1% (200/235), and 96.7% (436/451) post-implementation – only NPV was statistically different (P = 0.012). CT imaging after US decreased by 31% between pre- and post-implementation, 8.6% (106/1235) vs. 6.0% (41/686); P = 0.048). Negative appendectomy rates did not change (4.4% vs. 4.1%, P = 0.8).

Conclusion

A scoring system and structured template for reporting US exam results for suspected pediatric appendicitis was successfully adopted by a pediatric radiology department at a large tertiary children’s hospital and stratifies risk for children based on their likelihood of appendicitis.

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Title: Development and validation of an ultrasound scoring system for children with suspected acute appendicitis
Authors: Sara C. Fallon
Robert C. Orth
R. Paul Guillerman
Martha M. Munden
Wei Zhang
Simone C. Elder
Andrea T. Cruz
Mary L. Brandt
Monica E. Lopez
George S. Bisset
Publication date: 01-12-2015
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 13/2015
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-015-3443-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Development and validation of an ultrasound scoring system for children with suspected acute appendicitis

Abstract

Background

Objective

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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