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Published in: Pediatric Radiology 4/2015

Open Access 01-04-2015 | Minisymposium

Normal perinatal and paediatric postmortem magnetic resonance imaging appearances

Authors: Owen J. Arthurs, Joy L. Barber, Andrew M. Taylor, Neil J. Sebire

Published in: Pediatric Radiology | Issue 4/2015

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Abstract

As postmortem imaging becomes more widely used following perinatal and paediatric deaths, the correct interpretation of images becomes imperative, particularly given the increased use of postmortem magnetic resonance imaging. Many pathological processes may have similar appearances in life and following death. A thorough knowledge of normal postmortem changes is therefore required within postmortem magnetic resonance imaging to ensure that these are not mistakenly interpreted as significant pathology. Similarly, some changes that are interpreted as pathological if they occur during life may be artefacts on postmortem magnetic resonance imaging that are of limited significance. This review serves to illustrate briefly those postmortem magnetic resonance imaging changes as part of the normal changes after death in fetuses and children, and highlight imaging findings that may confuse or mislead an observer to identifying pathology where none is present.
Literature
1.
go back to reference Thayyil S, Sebire NJ, Chitty LS et al (2013) Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study. Lancet 382:223–233CrossRefPubMed Thayyil S, Sebire NJ, Chitty LS et al (2013) Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study. Lancet 382:223–233CrossRefPubMed
2.
go back to reference Christe A, Flach P, Ross S et al (2010) Clinical radiology and postmortem imaging (Virtopsy) are not the same: Specific and unspecific postmortem signs. Leg Med Tokyo 12:215–222CrossRefPubMed Christe A, Flach P, Ross S et al (2010) Clinical radiology and postmortem imaging (Virtopsy) are not the same: Specific and unspecific postmortem signs. Leg Med Tokyo 12:215–222CrossRefPubMed
3.
go back to reference Keeling JW, Yee Khong T (2007) Fetal and perinatal pathology, 4th edn. Springer, LondonCrossRef Keeling JW, Yee Khong T (2007) Fetal and perinatal pathology, 4th edn. Springer, LondonCrossRef
4.
go back to reference Genest DR, Singer DB (1992) Estimating the time of death in stillborn fetuses: III. external fetal examination; a study of 86 stillborns. Obstet Gynecol 80:593–600PubMed Genest DR, Singer DB (1992) Estimating the time of death in stillborn fetuses: III. external fetal examination; a study of 86 stillborns. Obstet Gynecol 80:593–600PubMed
5.
go back to reference Genest DR, Williams MA, Greene MF (1992) Estimating the time of death in stillborn fetuses: I. Histologic evaluation of fetal organs; an autopsy study of 150 stillborns. Obstet Gynecol 80:575–584PubMed Genest DR, Williams MA, Greene MF (1992) Estimating the time of death in stillborn fetuses: I. Histologic evaluation of fetal organs; an autopsy study of 150 stillborns. Obstet Gynecol 80:575–584PubMed
6.
go back to reference Carroll SG, Porter H, Abdel-Fattah S et al (2000) Correlation of prenatal ultrasound diagnosis and pathologic findings in fetal brain abnormalities. Ultrasound Obstet Gynecol 16:149–153CrossRefPubMed Carroll SG, Porter H, Abdel-Fattah S et al (2000) Correlation of prenatal ultrasound diagnosis and pathologic findings in fetal brain abnormalities. Ultrasound Obstet Gynecol 16:149–153CrossRefPubMed
7.
go back to reference Winsor EJ, Windrim R, Chitayat D et al (2005) Success rate for culture of fetal postmortem tissue is dependent on the method of pregnancy termination. Fetal Diagn Ther 20:306–308CrossRefPubMed Winsor EJ, Windrim R, Chitayat D et al (2005) Success rate for culture of fetal postmortem tissue is dependent on the method of pregnancy termination. Fetal Diagn Ther 20:306–308CrossRefPubMed
8.
go back to reference Hughes-Roberts Y et al (2012) Post-mortem skeletal surveys in suspected non-accidental injury. Clin Radiol 67:868–876CrossRefPubMed Hughes-Roberts Y et al (2012) Post-mortem skeletal surveys in suspected non-accidental injury. Clin Radiol 67:868–876CrossRefPubMed
9.
go back to reference Thayyil S, De Vita E, Sebire NJ et al (2012) Post-mortem cerebral magnetic resonance imaging T1 and T2 in fetuses, newborns and infants. Eur J Radiol 81:e232–238CrossRefPubMed Thayyil S, De Vita E, Sebire NJ et al (2012) Post-mortem cerebral magnetic resonance imaging T1 and T2 in fetuses, newborns and infants. Eur J Radiol 81:e232–238CrossRefPubMed
10.
go back to reference Scheurer E, Lovblad KO, Kreis R et al (2011) Forensic application of postmortem diffusion-weighted and diffusion tensor MR imaging of the human brain in situ. AJNR Am J Neuroradiol 32:1518–1524CrossRefPubMed Scheurer E, Lovblad KO, Kreis R et al (2011) Forensic application of postmortem diffusion-weighted and diffusion tensor MR imaging of the human brain in situ. AJNR Am J Neuroradiol 32:1518–1524CrossRefPubMed
11.
12.
go back to reference Robinson C, Biggs MJ, Amoroso J et al (2014) Post-mortem computed tomography ventilation; simulating breath holding. Int J Legal Med 128:139–146CrossRefPubMed Robinson C, Biggs MJ, Amoroso J et al (2014) Post-mortem computed tomography ventilation; simulating breath holding. Int J Legal Med 128:139–146CrossRefPubMed
13.
go back to reference Jackowski C, Thali M, Aghayev E et al (2006) Postmortem imaging of blood and its characteristics using MSCT and MRI. Int J Legal Med 120:233–240CrossRefPubMed Jackowski C, Thali M, Aghayev E et al (2006) Postmortem imaging of blood and its characteristics using MSCT and MRI. Int J Legal Med 120:233–240CrossRefPubMed
14.
go back to reference Shiotani S, Kohno M, Ohashi N et al (2002) Postmortem intravascular high-density fluid level (hypostasis): CT findings. J Comput Assist Tomogr 26:892–893CrossRefPubMed Shiotani S, Kohno M, Ohashi N et al (2002) Postmortem intravascular high-density fluid level (hypostasis): CT findings. J Comput Assist Tomogr 26:892–893CrossRefPubMed
15.
go back to reference Laurent PE, Coulange M, Bartoli C et al (2013) Appearance of gas collections after scuba diving death: a computed tomography study in a porcine model. Int J Legal Med 127:177–184CrossRefPubMed Laurent PE, Coulange M, Bartoli C et al (2013) Appearance of gas collections after scuba diving death: a computed tomography study in a porcine model. Int J Legal Med 127:177–184CrossRefPubMed
16.
go back to reference Charlier P, Carlier R, Roffi F et al (2012) Postmortem abdominal CT: assessing normal cadaveric modifications and pathological processes. Eur J Radiol 81:639–647CrossRefPubMed Charlier P, Carlier R, Roffi F et al (2012) Postmortem abdominal CT: assessing normal cadaveric modifications and pathological processes. Eur J Radiol 81:639–647CrossRefPubMed
17.
go back to reference Weber MA, Ashworth MT, Risdon RA et al (2008) The role of post-mortem investigations in determining the cause of sudden unexpected death in infancy. Arch Dis Child 93:1048–1053CrossRefPubMed Weber MA, Ashworth MT, Risdon RA et al (2008) The role of post-mortem investigations in determining the cause of sudden unexpected death in infancy. Arch Dis Child 93:1048–1053CrossRefPubMed
18.
go back to reference Zizka J, Elias P, Hodik K et al (2006) Liver, meconium, haemorrhage: the value of T1-weighted images in fetal MRI. Pediatr Radiol 36:792–801CrossRefPubMed Zizka J, Elias P, Hodik K et al (2006) Liver, meconium, haemorrhage: the value of T1-weighted images in fetal MRI. Pediatr Radiol 36:792–801CrossRefPubMed
19.
go back to reference Laczniak AN, Sato Y, Nashelsky M (2011) Postmortem gastric perforation (gastromalacia) mimicking abusive injury in sudden unexplained infant death. Pediatr Radiol 41:1595–1597CrossRefPubMed Laczniak AN, Sato Y, Nashelsky M (2011) Postmortem gastric perforation (gastromalacia) mimicking abusive injury in sudden unexplained infant death. Pediatr Radiol 41:1595–1597CrossRefPubMed
Metadata
Title
Normal perinatal and paediatric postmortem magnetic resonance imaging appearances
Authors
Owen J. Arthurs
Joy L. Barber
Andrew M. Taylor
Neil J. Sebire
Publication date
01-04-2015
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 4/2015
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-014-3166-y

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