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01-03-2015 | Case Report

Canavan disease – unusual imaging features in a child with mild clinical presentation

Authors: Ho V. Nguyen, Gisele E. Ishak

Published in: Pediatric Radiology | Issue 3/2015

Abstract

Canavan disease is a rare hereditary leukodystrophy that manifests in early childhood. Associated with rapidly progressive clinical deterioration, it usually results in death by the third year of life. The predominant MRI appearance is diffuse and symmetrical white matter disease. We discuss an atypical, late presentation of Canavan disease with a benign clinical course and uncharacteristic imaging features. This case introduces a previously unreported pattern of diffuse cortical abnormality without significant white matter involvement.

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Title: Canavan disease – unusual imaging features in a child with mild clinical presentation
Authors: Ho V. Nguyen
Gisele E. Ishak
Publication date: 01-03-2015
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 3/2015
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-014-3116-8

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Springer Medicine

Canavan disease – unusual imaging features in a child with mild clinical presentation

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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