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01-10-2012 | Original Article

The impact of preparation and support procedures for children with sickle cell disease undergoing MRI

Authors: Katherine R. Cejda, Matthew P. Smeltzer, Eileen N. Hansbury, Mary Elizabeth McCarville, Kathleen J. Helton, Jane S. Hankins

Published in: Pediatric Radiology | Issue 10/2012

Abstract

Background

Children with sickle cell disease (SCD) often undergo MRI studies to assess brain injury or to quantify hepatic iron. MRI requires the child to lie motionless for 30–60 min, thus sedation/anesthesia might be used to facilitate successful completion of exams, but this poses additional risks for SCD patients. To improve children’s ability to cope with MRI examinations and avoid sedation, our institution established preparation and support procedures (PSP).

Objective

To investigate the impact of PSP in reducing the need for sedation during MRI exams among children with SCD.

Materials and methods

Data on successful completion of MRI testing were compared among 5- to 12-year-olds who underwent brain MRI or liver R2*MRI with or without receiving PSP.

Results

Seventy-one children with SCD (median age 9.85 years, range 5.57–12.99 years) underwent a brain MRI (n = 60) or liver R2*MRI (n = 11). Children who received PSP were more likely to complete an interpretable MRI exam than those who did not (30 of 33; 91% vs. 27 of 38; 71%, unadjusted OR = 4.1 (P = 0.04) and OR = 8.5 (P < 0.01) when adjusting for age.

Conclusion

PSP can help young children with SCD complete clinically interpretable, nonsedated MRI exams, avoiding the risks of sedation/anesthesia.

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Title: The impact of preparation and support procedures for children with sickle cell disease undergoing MRI
Authors: Katherine R. Cejda
Matthew P. Smeltzer
Eileen N. Hansbury
Mary Elizabeth McCarville
Kathleen J. Helton
Jane S. Hankins
Publication date: 01-10-2012
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 10/2012
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-012-2422-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The impact of preparation and support procedures for children with sickle cell disease undergoing MRI

Abstract

Background

Objective

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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