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Pediatric Radiology

Published in:

01-03-2012 | Original Article

Rapidly involuting congenital haemangioma (RICH) of the liver

Authors: Derek Roebuck, Neil Sebire, Eldon Lehmann, Alex Barnacle

Published in: Pediatric Radiology | Issue 3/2012

Abstract

Background

Rapidly involuting congenital haemangioma (RICH) is a benign neoplasm that may occur in many locations in the body. When RICH occurs in the liver, it may be confused with other lesions.

Objective

To present a case series from a single institution.

Materials and methods

Retrospective review of pathological and imaging findings in infants with biopsy-proven hepatic RICH treated at a single hospital.

Results

Four children (2 days to 6 weeks of age) presented between 2002 and 2007 with a solitary hepatic lesion. Needle biopsy excluded the alternative possibility of infantile haemangioma by showing negativity for GLUT1. Serial imaging confirmed rapid involution in each child.

Conclusion

RICH should be suspected in neonates who present with a solitary liver lesion and normal-for-age serum alpha-fetoprotein. Serial US scans should be used to confirm a progressive shrinkage of the lesion. Corticosteroids and β₂-adrenergic antagonists have no proven effect in treating RICH. If the lesion grows, percutaneous needle biopsy is recommended to exclude a malignant tumour and to direct further management. Infants with cardiac failure should be treated medically. Embolization (with or without needle biopsy) should only be performed when this strategy fails.

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Title: Rapidly involuting congenital haemangioma (RICH) of the liver
Authors: Derek Roebuck
Neil Sebire
Eldon Lehmann
Alex Barnacle
Publication date: 01-03-2012
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 3/2012
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-011-2268-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Rapidly involuting congenital haemangioma (RICH) of the liver

Abstract

Background

Objective

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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