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01-07-2008 | Case Report

Arterial aneurysms and tuberous sclerosis: a classic but little known association

Authors: Giulio Calcagni, Francesco Gesualdo, Daniel Tamisier, Francis Brunelle, Daniel Sidi, Phalla Ou

Published in: Pediatric Radiology | Issue 7/2008

Abstract

Tuberous sclerosis is a rare autosomal dominant syndrome in which aortic aneurysm is a classic but little known cause of sudden death. We report a 20-month-old boy with tuberous sclerosis and iliofemoral arterial aneurysms. This case highlights the importance of systematic screening for such vascular complications. Multislice CT or MRI is mandatory as a screening and diagnostic tool in this setting to complement US with Doppler examination.

Von Recklinghausen F (1862) Ein Herz von einem Neugeborenen, welches mehrere Theils nach aussen, Theils nach den Höhlen prominirende Tumoren trug. Monatschr Geburtsk 21:1–3

Bourneville DM (1880) Contributions à l’étude de l’idiote. Sclerose tubereuse des circonvolution cerebrales; idiote et epilepsie hemiplegie. Arch Neurol 1:81–82

Weiner DM, Ewalt DH, Roach ES et al (1998) The tuberous sclerosis complex: a comprehensive review. J Am Coll Surg 187:548–561PubMedCrossRef

Jost CJ, Gloviczki P, Edward WD et al (2001) Aortic aneurysm in children and young adults with tuberous sclerosis: report of two cases and review of the literature. J Vasc Surg 33:639–642PubMedCrossRef

Beltramello A, Puppini G, Bricolo A et al (1999) Does the tuberous sclerosis complex include intracranial aneurysm? Pediatr Radiol 29:206–211PubMedCrossRef

Carette MF, Antoine M, Bazelly B et al (2006) Primary pulmonary artery aneurysm in tuberous sclerosis: CT, angiography and pathological study. Eur Radiol 16:2369–2370PubMedCrossRef

Shepherd CW, Gomez MR, Lie JT et al (1991) Cause of death in patients with tuberous sclerosis. Mayo Clinic Proc 66:792–796

Ewalt DH, Sheffield E, Sparagana SP et al (1998) Renal lesion growth in children with tuberous sclerosis complex. J Urol 160:141–145PubMedCrossRef

Tamisier D, Goutière F, Sidi D et al (1997) Abdominal aortic aneurysm in a child with tuberous sclerosis. Ann Vasc Surg 11:637–639PubMedCrossRef

Title: Arterial aneurysms and tuberous sclerosis: a classic but little known association
Authors: Giulio Calcagni
Francesco Gesualdo
Daniel Tamisier
Francis Brunelle
Daniel Sidi
Phalla Ou
Publication date: 01-07-2008
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 7/2008
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-008-0813-1

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Arterial aneurysms and tuberous sclerosis: a classic but little known association

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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