Published in:
01-10-2006 | Case Report
Liver involvement in Langerhans cell histiocytosis
Authors:
Adelaine Wong, Clara L. Ortiz-Neira, Walid Abou Reslan, Raphael Sharon, Alfredo Pinto-Rojas, Deepak Kaura, Ronald Anderson
Published in:
Pediatric Radiology
|
Issue 10/2006
Login to get access
Abstract
Liver involvement in Langerhans cell histiocytosis (LCH) typically presents with hepatomegaly and other signs of liver dysfunction. We present an 11-month-old child having only minimally elevated liver enzymes as an indication of liver involvement. Using sonography as the initial diagnostic tool followed by MRI, LCH of the liver was revealed. A review of sonographic, CT, MRI and MR cholangiopancreatography findings in liver LCH is presented. We recommend that physicians consider sonography and MRI screening for liver involvement in patients with newly diagnosed LCH, as periportal involvement may be present with little or no liver function abnormality present, as in this patient.