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Published in:

01-04-2013 | Review Article

Dexmedetomidine: Antiarrhythmic Effects in the Pediatric Cardiac Patient

Authors: Joseph D. Tobias, Constantinos Chrysostomou

Published in: Pediatric Cardiology | Issue 4/2013

Abstract

This report aims to provide a general description of the cardiovascular effects of dexmedetomidine, emphasizing its effects on conduction, and to give an evidence-based review of the literature regarding the use of dexmedetomidine to treat and prevent tachyarrhythmias in infants and children. A computerized bibliographic search of the literature on the use of dexmedetomidine to treat and prevent arrhythmias in infants and children was conducted. The cardiovascular effects of dexmedetomidine have been well studied in animal and adult human models. Growing experience, mostly in the pediatric population, has demonstrated the potential therapeutic applications of dexmedetomidine in the acute treatment of arrhythmias. Additionally, its use during cardiac surgery has been associated with a decreased incidence of postoperative ventricular and supraventricular tachyarrhythmias. Although dexmedetomidine is not currently approved by the Food and Drug Administration for the pediatric population, findings have shown it to be effective in various clinical scenarios for sedation. In addition, recent studies show that dexmedetomidine may have promising properties for the acute treatment and prevention of tachyarrhythmias.

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Title: Dexmedetomidine: Antiarrhythmic Effects in the Pediatric Cardiac Patient
Authors: Joseph D. Tobias
Constantinos Chrysostomou
Publication date: 01-04-2013
Publisher: Springer-Verlag
Published in: Pediatric Cardiology / Issue 4/2013
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI: https://doi.org/10.1007/s00246-013-0659-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Dexmedetomidine: Antiarrhythmic Effects in the Pediatric Cardiac Patient

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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