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Published in: Pediatric Cardiology 2/2007

01-04-2007

Neurodevelopmental Outcomes Following Congenital Heart Surgery

Authors: Jean A. Ballweg, Gil Wernovsky, J. William Gaynor

Published in: Pediatric Cardiology | Issue 2/2007

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Abstract

Advances in both surgical techniques and perioperative care have led to improved survival outcomes in infants and children undergoing surgery for complex congenital heart disease. An awareness is emerging that early and late neurological morbidities complicate the outcome of these operations. Adverse neurological outcomes after neonatal and infant cardiac surgery are related to both fixed and modifiable mechanisms. Fixed factors include many variables specific to the individual patient, including genetic predisposition, gender, race, socioeconomic status, and in utero central nervous system development. Modifiable factors include not only intraoperative variables (cardiopulmonary bypass, deep hypothermic circulatory arrest, and hemodilution) but also such variables as hypoxemia, hypotension, and low cardiac output. The purpose of this review is to examine these mechanisms as they relate to available outcome data.
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Metadata
Title
Neurodevelopmental Outcomes Following Congenital Heart Surgery
Authors
Jean A. Ballweg
Gil Wernovsky
J. William Gaynor
Publication date
01-04-2007
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 2/2007
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-006-1450-9

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