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01-06-2014 | Original Paper

Titanium-coated polypropylene mesh (TiLoop Bra®)—an effective prevention for capsular contracture?

Authors: Philipp A. Bergmann, Benedikt Becker, Karl L. Mauss, Maria E. Liodaki, Johannes Knobloch, Peter Mailänder, Frank Siemers

Published in: European Journal of Plastic Surgery | Issue 6/2014

Abstract

Background

Silicone implants have been used in breast augmentation for more than 45 years. Complications, in particular, capsular contracture, still occur with a high incidence. Titanium-coated polypropylene mesh (TCPM; TiLoop Bra®, pfm medical, Cologne, Germany) provides new opportunities for implant-based breast reconstruction. We investigated the influence of the surface of silicone implants on the formation of capsular contracture by comparing textured silicone with TCPM-covered smooth silicone implants.

Methods

Twenty textured silicone gel-filled (group A) and twenty TCPM-covered smooth silicone gel implants (group B) (Silimed®, Rio de Janeiro, Brazil) were implanted in female Wistar rats. After 60 days, the implants and capsules were extracted, and histological and immunohistochemical staining was performed. The double-blind evaluation of the capsules was performed by two examiners.

Results

We were able to detect a thinner, but stiffer, capsule and a less development of an inner synovia metaplasia layer as well as a lower vascularity in capsules around TCPM-covered silicone implants. We found a higher percentage of myofibroblasts within the capsule structure and more inflammatory cell infiltration.

Conclusions

The quality of capsule structure around both tested implants differs significantly. Although capsules around TCPM-covered implants presented were thinner, they integrated with the mesh in a rigid cage structure capsule with higher infiltration of inflammatory cells caused by a significant foreign body reaction. TCPM-covered silicone implants showed no apparent advantage in the reduction of capsular contracture. On the other hand, the indication for using this material as a supportive soft tissue structure can be confirmed.

Level of Evidence: not ratable, experimental study.

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Title: Titanium-coated polypropylene mesh (TiLoop Bra®)—an effective prevention for capsular contracture?
Authors: Philipp A. Bergmann
Benedikt Becker
Karl L. Mauss
Maria E. Liodaki
Johannes Knobloch
Peter Mailänder
Frank Siemers
Publication date: 01-06-2014
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Plastic Surgery / Issue 6/2014
Print ISSN: 0930-343X
Electronic ISSN: 1435-0130
DOI: https://doi.org/10.1007/s00238-014-0947-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Titanium-coated polypropylene mesh (TiLoop Bra®)—an effective prevention for capsular contracture?

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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