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01-10-2014 | Diagnostic Neuroradiology

Vertebral artery variations and osseous anomaly at the C1-2 level diagnosed by 3D CT angiography in normal subjects

Authors: Norimitsu Wakao, Mikinobu Takeuchi, Manabu Nishimura, K. Daniel Riew, Mitsuhiro Kamiya, Atsuhiko Hirasawa, Katsuhisa Kawanami, Shiro Imagama, Keiji Sato, Masakazu Takayasu

Published in: Neuroradiology | Issue 10/2014

Abstract

Introduction

The craniovertebral junction is anatomically complicated. Representative vertebral artery (VA) variations include the persistent first intersegmental artery (FIA), fenestration of the VA above and below C1 (FEN), posterior inferior cerebellar artery (PICA) from C1/2, and high-riding VA (HRVA). The ponticulus posticus (PP) is a well-known osseous anomaly at C1. Although those anomalies are frequent in patients with cervical deformity, the prevalence of these in subjects with normal cervical spines is still unknown. The aim of this study is to investigate the variations and prevalence of vascular and osseous anomalies based on three-dimensional computed tomographic (3D CT) angiography in patients without any cervical diseases, such as rheumatoid arthritis, Klippel-Feil syndrome, or Down syndrome.

Methods

Eligible subjects were patients who underwent 3D CT angiography by the Department of Otorhinolaryngology and Internal Medicine from January 2009 to October 2013 in our institution. The authors defined a HRVA as a C2 pedicle with a maximum diameter of 4 mm or less.

Results

Among 480 subjects with a mean age of 63.1 years, 387 patients were eligible. One hundred and eighteen subjects were female, and 269 were male. HRVA was observed in 10.1 % of patients (39 out of 387 cases), FIA in 1.8 % (7 cases), FEN in 1.3 % (5 cases), and PICA in 1.3 % (5 cases). PP was observed in 6.2 % of patients (24 cases).

Conclusion

According to past reports, many VA anomalies could be attributed to congenital or acquired conditions (e.g., rheumatoid arthritis). However, VA anomalies appear to exist even in patients without any such cervical diseases.

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Title: Vertebral artery variations and osseous anomaly at the C1-2 level diagnosed by 3D CT angiography in normal subjects
Authors: Norimitsu Wakao
Mikinobu Takeuchi
Manabu Nishimura
K. Daniel Riew
Mitsuhiro Kamiya
Atsuhiko Hirasawa
Katsuhisa Kawanami
Shiro Imagama
Keiji Sato
Masakazu Takayasu
Publication date: 01-10-2014
Publisher: Springer Berlin Heidelberg
Published in: Neuroradiology / Issue 10/2014
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-014-1399-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Vertebral artery variations and osseous anomaly at the C1-2 level diagnosed by 3D CT angiography in normal subjects

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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