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Neuroradiology

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01-08-2008 | Interventional Neuroradiology

Long-term results with Matrix coils vs. GDC: an angiographic and histopathological comparison

Authors: C. Roth, T. Struffert, I. Q. Grunwald, B. F. M. Romeike, C. Krick, P. Papanagiotou, P. Krampe, W. Reith

Published in: Neuroradiology | Issue 8/2008

Abstract

Introduction

The aim of the study was to compare standard platinum Guglielmi detachable coils (GDC) with coated platinum coils (Matrix; both Boston Scientific, Fremont, CA) regarding handling, complications, occlusion and recanalization rate after 3 and 6Â months.

Methods

Aneurysms in the right common carotid artery were created in 25 rabbits. The animals were divided into five groups of five animals each. The animals of group 1 (the control group) received no treatment of the induced aneurysms, the animals of groups 2 and 3 (killed at 3 and 6Â months) were treated with standard GDC, and the animals of groups 4 and 5 (killed at 3 and 6Â months) were treated with Matrix coils.

Results

Histopathological evaluation showed organized thrombus formation and connective tissue with neovascularization around the implanted coils in all the treated groups. The achieved occlusion rates in groups 2 and 3 were identical to those in groups 4 and 5. Thus the long-term results of aneurysm treatment with GDC and Matrix coils show no differences regarding occlusion and recanalization rates. The only noticeable difference was the difference in handling. More force was required to pushing the Matrix coils forward through the microcatheter and there was more friction in coil interaction in the aneurysm.

Conclusion

The bioactive coating of the Matrix coil produces no significant benefit in achieving higher occlusion and lower recanalization rates, and the coil is more difficult to handle. Future bioactive coils must be shown to produce significantly better long-term results than GDC and their ease of handling has to be improved.

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Title: Long-term results with Matrix coils vs. GDC: an angiographic and histopathological comparison
Authors: C. Roth
T. Struffert
I. Q. Grunwald
B. F. M. Romeike
C. Krick
P. Papanagiotou
P. Krampe
W. Reith
Publication date: 01-08-2008
Publisher: Springer-Verlag
Published in: Neuroradiology / Issue 8/2008
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-008-0392-8

2024 ASCO Annual Meeting

Springer Medicine

Long-term results with Matrix coils vs. GDC: an angiographic and histopathological comparison

Abstract

Introduction

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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