Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Neuroradiology
Published in: Neuroradiology 1/2008

01-01-2008 | Diagnostic Neuroradiology

Clinical applications of diffusion tensor tractography of the spinal cord

Authors: Maria Isabel Vargas, Jacqueline Delavelle, Helmi Jlassi, Bénédict Rilliet, Magalie Viallon, Christoph D. Becker, Karl-Olof Lövblad

Published in: Neuroradiology | Issue 1/2008

Login to get access

Abstract

Diffusion tensor imaging (DTI) can visualize the white matter tracts in vivo. The aim of this study was to assess the clinical utility of DTI in patients with diseases of the spinal cord. Fourteen subjects underwent magnetic resonance imaging of the spine at 1.5 T. Preliminary diagnosis of the patients suggested traumatic, tumorous, ischemic or inflammatory lesions of the spinal cord. In addition to T2-weighted images, DTI was performed with the gradients in 30 orthogonal directions. Maps of the apparent diffusion coefficient and of fractional anisotropy were reconstructed. Diffusion tensor imaging showed a clear displacement and deformation of the white matter tracts at the level of the pathological lesions in the spinal cord. This capability of diffusion tensor imaging to reliably display secondary alterations to the white matter tracts caused by the primary lesion has the potential to be of great utility for treatment planning and follow-up.
Literature
1.
Thurnher MM, Bammer R (2006) Diffusion-weighted magnetic resonance imaging of the spine and spinal cord. Semin Roentgenol 41(4):294–311PubMedCrossRef
2.
Tsuchiya K, Katase S, Fujikawa A, Hachiya J, Kanazawa H, Yodo K (2003) Diffusion-weighted MRI of the cervical spinal cord using a single-shot fast spin-echo technique: findings in normal subjects and in myelomalacia. Neuroradiology 45(2):90–94PubMed
3.
Stepper F, Lovblad KO (2001) Anterior spinal artery stroke demonstrated by echo-planar DWI. Eur Radiol 11(12):2607–2610PubMedCrossRef
4.
Le Bihan D, Mangin JF, Poupon C, Clark CA, Pappata S, Molko N, Chabriat H (2001) Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 13(4):534–546PubMedCrossRef
5.
Maier SE, Mamata H (2005) Diffusion tensor imaging of the spinal cord. Ann N Y Acad Sci 1064:50–60PubMedCrossRef
6.
Summers P, Staempfli P, Jaermann T, Kwiecinski S, Kollias S (2006) A preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cord. Am J Neuroradiol 27(9):1952–1961PubMed
7.
Rossi C, Boss A, Lindig TM, Martirosian P, Steidle G, Maetzler W, Claussen CD, Klose U, Schick F (2007) Diffusion tensor imaging of the spinal cord at 1.5 and 3.0 Tesla. ROFO 179(3):219–224PubMed
8.
Ducreux D, Lepeintre JF, Fillard P, Loureiro C, Tadie M, Lasjaunias P (2006) MR diffusion tensor imaging and fiber tracking in 5 spinal cord astrocytomas. Am J Neuroradiol 2006 27(1):214–216
9.
Renoux J, Facon D, Fillard P, Huynh I, Lasjaunias P, Ducreux D (2006) MR diffusion tensor imaging and fiber tracking in inflammatory diseases of the spinal cord. Am J Neuroradiol 27(9):1947–1951PubMed
10.
Schwartz ED, Duda J, Shumsky JS, Cooper ET, Gee J (2005) Spinal cord diffusion tensor imaging and fiber tracking can identify white matter tract disruption and glial scar orientation following lateral funiculotomy. J Neurotrauma 22(12):1388–1398PubMedCrossRef
11.
Deo AA, Grill RJ, Hasan KM, Narayana PA (2006) In vivo serial diffusion tensor imaging of experimental spinal cord injury. J Neurosci Res 83(5):801–810PubMedCrossRef
12.
Loher TJ, Bassetti CL, Lovblad KO, Stepper FP, Sturzenegger M, Kiefer C, Nedeltchev K, Arnold M, Remonda L, Schroth G (2003) Diffusion-weighted MRI in acute spinal cord ischaemia. Neuroradiology 45(8):557–561PubMedCrossRef
Metadata
Title
Clinical applications of diffusion tensor tractography of the spinal cord
Authors
Maria Isabel Vargas
Jacqueline Delavelle
Helmi Jlassi
Bénédict Rilliet
Magalie Viallon
Christoph D. Becker
Karl-Olof Lövblad
Publication date
01-01-2008
Publisher
Springer-Verlag
Published in
Neuroradiology / Issue 1/2008
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-007-0309-y

Other articles of this Issue 1/2008

Neuroradiology 1/2008 Go to the issue

Interventional Neuroradiology

Angiographic and histological comparison of canine bifurcation aneurysms treated with first generation matrix and standard GDC coils

Society News

European Society of Neuroradiology (ESNR)

Interventional Neuroradiology

Intra-arterial thrombolysis using rt-PA in patients with acute stroke due to vessel occlusion of anterior and/or posterior cerebral circulation

Diagnostic Neuroradiology

High-field, high-resolution, susceptibility-weighted magnetic resonance imaging: improved image quality by addition of contrast agent and higher field strength in patients with brain tumors

Diagnostic Neuroradiology

The basal ganglia: a substrate for fatigue in multiple sclerosis

Paediatric Neuroradiology

Paediatric neuroradiological aspects of Langerhans cell histiocytosis