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Neuroradiology

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01-10-2007 | Interventional Neuroradiology

Use of Glubran 2 acrylic glue in interventional neuroradiology

Authors: L. Raffi, L. Simonetti, P. Cenni, M. Leonardi

Published in: Neuroradiology | Issue 10/2007

Abstract

Introduction

Glubran 2 is a cyanoacrylate-based synthetic glue modified by the addition of a monomer synthesized by the manufacturer. With this material it is possible to obtain the stability of endovascular embolization that is needed to treat tumours and vascular disease.

Material and methods

We report our 3-year experience of the use of Glubran for treating extracerebral tumours, spinal tumours, spinal arteriovenous malformations, and brain and spine dural fistulae. Glubran 2 was diluted with Lipiodol and injected in a continuous column with the flow rate monitored by seriography. The injection was stopped when retrograde flow was displayed in the afferent vessel.

Results

There were no periprocedural or subsequent clinical complications and the glue resulted in successful selective permanent occlusion with intralesional penetration similar to the angiographic features of microcatheterization.

Conclusions

The embolization procedure was technically straightforward and relatively safe. However, Glubran 2 can be difficult to use and the procedure does carry major risks for patients. Glue injection requires in-depth study of the lesion, its circulation and the collateral circulation to avoid severe complications due to inappropriate use.

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Title: Use of Glubran 2 acrylic glue in interventional neuroradiology
Authors: L. Raffi
L. Simonetti
P. Cenni
M. Leonardi
Publication date: 01-10-2007
Publisher: Springer-Verlag
Published in: Neuroradiology / Issue 10/2007
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-007-0238-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Use of Glubran 2 acrylic glue in interventional neuroradiology

Abstract

Introduction

Material and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Material and methods

Results

Conclusions

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