Skip to main content
Top
Published in: Neuroradiology 9/2003

01-09-2003 | Diagnostic Neuroradiology

Echoplanar diffusion-weighted MRI with intravenous gadolinium-DTPA

Authors: C. Fitzek, H. J. Mentzel, S. Fitzek, D. Sauner, W. A. Kaiser, J. R. Reichenbach

Published in: Neuroradiology | Issue 9/2003

Login to get access

Abstract

It is occasionally necessary to repeat diffusion weighted imaging (DWI) after giving intravenous contrast medium (CM). However, the effects of CM on DWI and apparent diffusion coefficients (ADC) have not been fully examined. The aim of this prospective study was to investigate whether there are any diagnostically significant differences between echo-planar imaging (EPI)-DWI before and after intravenous CM. EPI-DWI was acquired twice in 203 consecutive patients before and after i.v. CM. Three blinded readers rated the diagnostic image quality. Quantitative ADC calculations were performed before and after CM in all 72 patients with lesions sufficiently large for quantification, and in 72 normal brain regions. Of the 203 patients, 127 had abnormalities on MRI, including ischaemic stroke (52), bleeding (nine), brain tumour with disturbed blood-brain barrier (BBB) (18) and other lesions (48). There were no significant signal differences on isotropic DWI before and after CM, even in lesions with definite disturbance of the BBB. No statistically significant difference between ADC of lesions and contralateral normal brain was observed.
Literature
1.
go back to reference Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M (1986) MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 161: 401–407PubMed Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M (1986) MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 161: 401–407PubMed
2.
go back to reference Fitzek C, Tintera J, Muller-Forell W, et al (1998) Differentiation of recent and old cerebral infarcts by diffusion- weighted MRI. Neuroradiology 40: 778–782PubMed Fitzek C, Tintera J, Muller-Forell W, et al (1998) Differentiation of recent and old cerebral infarcts by diffusion- weighted MRI. Neuroradiology 40: 778–782PubMed
3.
go back to reference Fiebach J, Jansen O, Schellinger P, et al (2001) Comparison of CT with diffusion-weighted MRI in patients with hyperacute stroke. Neuroradiology 43: 628–632PubMed Fiebach J, Jansen O, Schellinger P, et al (2001) Comparison of CT with diffusion-weighted MRI in patients with hyperacute stroke. Neuroradiology 43: 628–632PubMed
4.
go back to reference Urbach H, Flacke S, Keller E, et al (2000) Detectability and detection rate of acute cerebral hemisphere infarcts on CT and diffusion-weighted MRI. Neuroradiology 42: 722–727CrossRefPubMed Urbach H, Flacke S, Keller E, et al (2000) Detectability and detection rate of acute cerebral hemisphere infarcts on CT and diffusion-weighted MRI. Neuroradiology 42: 722–727CrossRefPubMed
5.
go back to reference Wiener JI, King JT, Jr., Moore JR, Lewin JS (2001) The value of diffusion-weighted imaging for prediction of lasting deficit in acute stroke: an analysis of 134 patients with acute neurologic deficits. Neuroradiology 43: 435–441CrossRefPubMed Wiener JI, King JT, Jr., Moore JR, Lewin JS (2001) The value of diffusion-weighted imaging for prediction of lasting deficit in acute stroke: an analysis of 134 patients with acute neurologic deficits. Neuroradiology 43: 435–441CrossRefPubMed
6.
go back to reference Fitzek C, Mewes T, Fitzek S, Mentzel HJ, Hunsche S, Stoeter P (2002) Diffusion-weighted MRI of cholesteatomas of the petrous bone. J Magn Reson Imaging 15: 636–641CrossRefPubMed Fitzek C, Mewes T, Fitzek S, Mentzel HJ, Hunsche S, Stoeter P (2002) Diffusion-weighted MRI of cholesteatomas of the petrous bone. J Magn Reson Imaging 15: 636–641CrossRefPubMed
7.
go back to reference Hartmann M, Heiland S, Sartor K (2002) Functional MRI procedures in the diagnosis of brain tumours: Perfusion- and diffusion-weighted imaging. Rofo 174: 955–964CrossRef Hartmann M, Heiland S, Sartor K (2002) Functional MRI procedures in the diagnosis of brain tumours: Perfusion- and diffusion-weighted imaging. Rofo 174: 955–964CrossRef
8.
go back to reference Chang SC, Lai PH, Chen WL, et al (2002) Diffusion-weighted MRI features of brain abscess and cystic or necrotic brain tumors: comparison with conventional MRI. Clin Imaging 26: 227–236CrossRefPubMed Chang SC, Lai PH, Chen WL, et al (2002) Diffusion-weighted MRI features of brain abscess and cystic or necrotic brain tumors: comparison with conventional MRI. Clin Imaging 26: 227–236CrossRefPubMed
9.
go back to reference Tsuruda JS, Chew WM, Moseley ME, Norman D (1990) Diffusion-weighted MR imaging of the brain: value of differentiating between extraaxial cysts and epidermoid tumors. Am J Roentgenol 155: 1059–1068PubMed Tsuruda JS, Chew WM, Moseley ME, Norman D (1990) Diffusion-weighted MR imaging of the brain: value of differentiating between extraaxial cysts and epidermoid tumors. Am J Roentgenol 155: 1059–1068PubMed
10.
go back to reference Tzika AA, Zarifi MK, Goumnerova L, et al (2002) Neuroimaging in pediatric brain tumors: Gd-DTPA-enhanced, hemodynamic, and diffusion MR imaging compared with MR spectroscopic imaging. AJNR 23: 322–333 Tzika AA, Zarifi MK, Goumnerova L, et al (2002) Neuroimaging in pediatric brain tumors: Gd-DTPA-enhanced, hemodynamic, and diffusion MR imaging compared with MR spectroscopic imaging. AJNR 23: 322–333
11.
go back to reference Hartmann M, Jansen O, Heiland S, Sommer C, Munkel K, Sartor K (2001) Restricted diffusion within ring enhancement is not pathognomonic for brain abscess. AJNR 22: 1738–1742 Hartmann M, Jansen O, Heiland S, Sommer C, Munkel K, Sartor K (2001) Restricted diffusion within ring enhancement is not pathognomonic for brain abscess. AJNR 22: 1738–1742
12.
go back to reference Fitzek C, Weissmann M, Speckter H, et al (2001) Anatomy of brain-stem white-matter tracts shown by diffusion-weighted imaging. Neuroradiology 43: 953–960CrossRefPubMed Fitzek C, Weissmann M, Speckter H, et al (2001) Anatomy of brain-stem white-matter tracts shown by diffusion-weighted imaging. Neuroradiology 43: 953–960CrossRefPubMed
13.
go back to reference Tourbah A, Stievenart JL, Abanou A, Fontaine B, Cabanis EA, Lyon-Caen O (2001) Correlating multiple MRI parameters with clinical features: an attempt to define a new strategy in multiple sclerosis. Neuroradiology 43: 712–720CrossRefPubMed Tourbah A, Stievenart JL, Abanou A, Fontaine B, Cabanis EA, Lyon-Caen O (2001) Correlating multiple MRI parameters with clinical features: an attempt to define a new strategy in multiple sclerosis. Neuroradiology 43: 712–720CrossRefPubMed
14.
go back to reference Flacke S, Wullner U, Keller E, Hamzei F, Urbach H (2000) Reversible changes in echo planar perfusion- and diffusion-weighted MRI in status epilepticus. Neuroradiology 42: 92–95PubMed Flacke S, Wullner U, Keller E, Hamzei F, Urbach H (2000) Reversible changes in echo planar perfusion- and diffusion-weighted MRI in status epilepticus. Neuroradiology 42: 92–95PubMed
15.
go back to reference Teixeira J, Zimmerman RA, Haselgrove JC, Bilaniuk LT, Hunter JV (2001) Diffusion imaging in pediatric central nervous system infections. Neuroradiology 43: 1031–1039CrossRefPubMed Teixeira J, Zimmerman RA, Haselgrove JC, Bilaniuk LT, Hunter JV (2001) Diffusion imaging in pediatric central nervous system infections. Neuroradiology 43: 1031–1039CrossRefPubMed
16.
go back to reference Inglese M, Salvi F, Iannucci G, Mancardi GL, Mascalchi M, Filippi M (2002) Magnetization transfer and diffusion tensor MR imaging of acute disseminated encephalomyelitis. AJNR 23: 267–272 Inglese M, Salvi F, Iannucci G, Mancardi GL, Mascalchi M, Filippi M (2002) Magnetization transfer and diffusion tensor MR imaging of acute disseminated encephalomyelitis. AJNR 23: 267–272
17.
go back to reference Liu AY, Maldjian JA, Bagley LJ, Sinson GP, Grossman RI (1999) Traumatic brain injury: diffusion-weighted MR imaging findings. AJNR 20: 1636–1641 Liu AY, Maldjian JA, Bagley LJ, Sinson GP, Grossman RI (1999) Traumatic brain injury: diffusion-weighted MR imaging findings. AJNR 20: 1636–1641
18.
go back to reference Guo AC, MacFall JR, Provenzale JM (2002) Multiple sclerosis: diffusion tensor MR imaging for evaluation of normal-appearing white matter. Radiology 222: 729–736PubMed Guo AC, MacFall JR, Provenzale JM (2002) Multiple sclerosis: diffusion tensor MR imaging for evaluation of normal-appearing white matter. Radiology 222: 729–736PubMed
19.
go back to reference Sener R (2002) Diffusion MRI in Rasmussen's encephalitis, herpes simplex encephalitis, and bacterial meningoencephalitis. Comput Med Imaging Graph 26: 327CrossRefPubMed Sener R (2002) Diffusion MRI in Rasmussen's encephalitis, herpes simplex encephalitis, and bacterial meningoencephalitis. Comput Med Imaging Graph 26: 327CrossRefPubMed
20.
go back to reference Sener RN (2001) Herpes simplex encephalitis: diffusion MR imaging findings. Comput Med Imaging Graph 25: 391–397CrossRefPubMed Sener RN (2001) Herpes simplex encephalitis: diffusion MR imaging findings. Comput Med Imaging Graph 25: 391–397CrossRefPubMed
21.
go back to reference Tsuchiya K, Katase S, Yoshino A, Hachiya J (1999) Diffusion-weighted MR imaging of encephalitis. Am J Roentgenol 173: 1097–1099 Tsuchiya K, Katase S, Yoshino A, Hachiya J (1999) Diffusion-weighted MR imaging of encephalitis. Am J Roentgenol 173: 1097–1099
22.
go back to reference Heiniger P, el-Koussy M, Schindler K, et al (2002) Diffusion and perfusion MRI for the localisation of epileptogenic foci in drug-resistant epilepsy. Neuroradiology 44: 475–480CrossRefPubMed Heiniger P, el-Koussy M, Schindler K, et al (2002) Diffusion and perfusion MRI for the localisation of epileptogenic foci in drug-resistant epilepsy. Neuroradiology 44: 475–480CrossRefPubMed
23.
go back to reference Yamada K, Kubota H, Kizu O, et al (2002) Effect of intravenous gadolinium-DTPA on diffusion-weighted images: evaluation of normal brain and infarcts. Stroke 33: 1799–1802CrossRefPubMed Yamada K, Kubota H, Kizu O, et al (2002) Effect of intravenous gadolinium-DTPA on diffusion-weighted images: evaluation of normal brain and infarcts. Stroke 33: 1799–1802CrossRefPubMed
24.
go back to reference Noguchi K, Watanabe N, Nagayoshi T, et al (1999) Role of diffusion-weighted echo-planar MRI in distinguishing between brain abscess and tumour: a preliminary report. Neuroradiology 41: 171–174PubMed Noguchi K, Watanabe N, Nagayoshi T, et al (1999) Role of diffusion-weighted echo-planar MRI in distinguishing between brain abscess and tumour: a preliminary report. Neuroradiology 41: 171–174PubMed
25.
go back to reference Brunberg JA, Chenevert TL, McKeever PE, et al (1995) In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in gliomas of the cerebral hemispheres. AJNR 16: 361–371PubMed Brunberg JA, Chenevert TL, McKeever PE, et al (1995) In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in gliomas of the cerebral hemispheres. AJNR 16: 361–371PubMed
26.
go back to reference Lansberg MG, Thijs VN, O'Brien MW, et al (2001) Evolution of apparent diffusion coefficient, diffusion-weighted, and T2- weighted signal intensity of acute stroke. AJNR 22: 637–644. Lansberg MG, Thijs VN, O'Brien MW, et al (2001) Evolution of apparent diffusion coefficient, diffusion-weighted, and T2- weighted signal intensity of acute stroke. AJNR 22: 637–644.
27.
go back to reference Helenius J, Soinne L, Perkio J, et al (2002) Diffusion-weighted MR imaging in normal human brains in various age groups. AJNR 23: 194–199 Helenius J, Soinne L, Perkio J, et al (2002) Diffusion-weighted MR imaging in normal human brains in various age groups. AJNR 23: 194–199
28.
go back to reference Zhong J, Kennan RP, Fulbright RK, Gore JC (1998) Quantification of intravascular and extravascular contributions to BOLD effects induced by alteration in oxygenation or intravascular contrast agents. Magn Reson Med 40: 526–536PubMed Zhong J, Kennan RP, Fulbright RK, Gore JC (1998) Quantification of intravascular and extravascular contributions to BOLD effects induced by alteration in oxygenation or intravascular contrast agents. Magn Reson Med 40: 526–536PubMed
Metadata
Title
Echoplanar diffusion-weighted MRI with intravenous gadolinium-DTPA
Authors
C. Fitzek
H. J. Mentzel
S. Fitzek
D. Sauner
W. A. Kaiser
J. R. Reichenbach
Publication date
01-09-2003
Publisher
Springer-Verlag
Published in
Neuroradiology / Issue 9/2003
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-003-0965-5

Other articles of this Issue 9/2003

Neuroradiology 9/2003 Go to the issue

Society News

September 2003

Announcements

September 2003