Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Neuroradiology
Published in: Neuroradiology 4/2003

01-04-2003 | Diagnostic Neuroradiology

Changes on diffusion-weighted MRI with focal motor status epilepticus: case report

Authors: P. Senn, K. O. Lövblad, D. Zutter, C. Bassetti, O. Zeller, F. Donati, G. Schroth

Published in: Neuroradiology | Issue 4/2003

Login to get access

Abstract

Transient imaging abnormalities, including changes on diffusion-weighted imaging (DWI), may be seen in focal status epilepticus. The changes on DWI provide am insight into the pathophysiology. We report a 53-year-old man with focal motor status epilepticus involving the left hand, arm and face with focal slowing on EEG. The apparent diffusion coefficients (ADC) were higher in the affected hemisphere than on the other side. At10 days and 6 weeks after the end of the seizures, we saw normal ADCs and atrophy of the affected hemisphere. We conclude that the MRI findings indicate both cytotoxic and vasogenic oedema during seizure activity and subsequent loss of brain parenchyma.
Literature
1.
Lansberg MG, O'Brien MW, Norbash AM, Moseley ME, Morrel M, Albers GW (1999) MRI abnormalities associated with partial status epilepticus. Neurology 52: 1021–1027
2.
Henry TR, Drury I, Brunberg JA, Pennell PB, McKeever PE, Beydoun A (1994) Focal cerebral magnetic resonance changes associated with partial status epilepticus. Epilepsia 35: 35–41
3.
Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M (1986) MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 161: 401–407
4.
van Gelderen P, de Vleeschouwer MHM, DesPres D, Pekar J, van Zijl PCM, Moonen CTW (1994) Water diffusion and acute stroke. MRM 31: 154–163
5.
Jakob PM, Lövblad KO, Weber J, et al (1998) Diffusionsgewichtete Bildgebung beim akuten Hirnschlag. Nervenarzt 69: 683–693
6.
Lövblad KO, Laubach HJ, Baird AE, et al (1998) Clinical experience with diffusion-weighted MR in patients with acute stroke. AJNR 19: 1061–1066
7.
Righini A, Pierpaoli C, Alger JR, Di Chiro G (1994) Brain parenchyma apparent diffusion coefficient alterations associated with experimental complex partial status epilepticus. Magn Reson Imaging 12: 865–871
8.
Wieshmann UC, Symms MR, Shorvon SD (1997) Diffusion changes in status epilepticus. Lancet 350: 493–494
9.
Cockerell OC, Rothwell J, Thompson PD, Marsden CD, Shorvon SD (1996) Clinical and physiological features of epilepsia partialis continua. Cases ascertained in the UK. Brain 119: 393–407
10.
Bartolomei F, Gavaret M, Dhiver C, et al (1999) Isolated, chronic, epilepsia partialis continua in an HIV-infected patient. Arch Neurol 56: 111–114
11.
Gambardella A, Pasquinelli G, Cittadella R, et al (1998) Kuf's disease presenting as late-onset epilepsia partialis continua. Neurology 51: 1180–1182
12.
Wang Y, Majors A, Najm I, et al (1995) Postictal alteration of sodium content and apparent diffusion coefficient in epileptic rat brain induced by kainic acid. Epilepsia 37: 1000–1006
13.
Zhong J, Petroff OAC, Prichard JW, Gore JC (1995) Barbiturate-reversible reduction of water diffusion coefficient in flurothyl-induced status epilepticus in rats. MRM 33: 253–256
14.
Sperk G, Lassmann H, Baran H, Kish SJ, Seitelberger F, Hornykiewicz O (1985) Kainic acid induced seizures: neurochemical and histopathological changes. Neuroscience 10: 1301–1315
15.
Olney JW, Fuller T, De Gubareff T (1979) Acute dendrotoxic changes in the hippocampus of kainate treated rats. Brain Res. 176: 91–100
16.
Schwob JE, Fuller T, Price JL, Olney JW (1980) Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: a histological study. Neuroscience 5: 991–1014
17.
Lassmann H, Petsche U, Kitz K, et al (1984) The role of brain edema in epileptic rat brain damage induced by systemic kainic acid injection. Neuroscience 13: 691–704
18.
Zucker DK, Wooten GF, Lothman EW (1983) Blood brain-barrier changes with kainic acid-induced limbic seizures. Exp Neurol 79: 422–433
Metadata
Title
Changes on diffusion-weighted MRI with focal motor status epilepticus: case report
Authors
P. Senn
K. O. Lövblad
D. Zutter
C. Bassetti
O. Zeller
F. Donati
G. Schroth
Publication date
01-04-2003
Publisher
Springer-Verlag
Published in
Neuroradiology / Issue 4/2003
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-002-0850-7

Other articles of this Issue 4/2003

Neuroradiology 4/2003 Go to the issue

Diagnostic Neuroradiology

Perfusion MRI in the evaluation of the relationship between tumour growth, necrosis and angiogenesis in glioblastomas and grade 1 meningiomas

Paediatric Neuroradiology

Incidental intracranial hemorrhage after uncomplicated birth: MRI before and after neonatal heart surgery

Book Review

Recent Literature

Diagnostic Neuroradiology

Diffusion-weighted MRI of haemangioblastomas and other cerebellar tumours

Diagnostic Neuroradiology

Cerebral Erdheim-Chester disease: case report and review of the literature

Diagnostic Neuroradiology

Internal carotid artery aneurysms, cranial nerve dysfunction and headache: the role of deformation and pulsation