Top

Published in:

Open Access 01-04-2015 | Research Article

Poor motor function is associated with reduced sensory processing after stroke

Authors: S. Floor Campfens, Sarah B. Zandvliet, Carel G. M. Meskers, Alfred C. Schouten, Michel J. A. M. van Putten, Herman van der Kooij

Published in: Experimental Brain Research | Issue 4/2015

Abstract

The possibility to regain motor function after stroke depends on the intactness of motor and sensory pathways. In this study, we evaluated afferent sensory pathway information transfer and processing after stroke with the coherence between cortical activity and a position perturbation (position-cortical coherence, PCC). Eleven subacute stroke survivors participated in this study. Subjects performed a motor task with the affected and non-affected arm while continuous wrist position perturbations were applied. Cortical activity was measured using EEG. PCC was calculated between position perturbation and EEG at the contralateral and ipsilateral sensorimotor area. The presence of PCC was quantified as the number of frequencies where PCC is larger than zero across the sensorimotor area. All subjects showed significant contralateral PCC in affected and non-affected wrist tasks. Subjects with poor motor function had a reduced presence of contralateral PCC compared with subjects with good motor function in the affected wrist tasks. Amplitude of significant PCC did not differ between subjects with good and poor motor function. Our results show that poor motor function is associated with reduced sensory pathway information transfer and processing in subacute stroke subjects. Position-cortical coherence may provide additional insight into mechanisms of recovery of motor function after stroke.

Baker SN (2007) Oscillatory interactions between sensorimotor cortex and the periphery. Curr Opin Neurobiol 17(6):649–655. doi:10.1016/j.conb.2008.01.007 CrossRefPubMedCentralPubMed

Bortel R, Sovka P (2007) Approximation of statistical distribution of magnitude squared coherence estimated with segment overlapping. Signal Process 87(5):1100–1117. doi:10.1016/j.sigpro.2006.10.003 CrossRef

Campfens SF, Schouten AC, van Putten MJAM, van der Kooij H (2013) Quantifying connectivity via efferent and afferent pathways in motor control using coherence measures and joint position perturbations. Exp Brain Res 228(2):141–153. doi:10.1007/s00221-013-3545-x CrossRefPubMed

Campfens SF, van der Kooij H, Schouten AC (2014) Face to phase: pitfalls in time delay estimation from coherency phase. J Comput Neurosci 37(1):1–8. doi:10.1007/s10827-013-0487-z PubMed

Connell LA, Lincoln NB, Radford KA (2008) Somatosensory impairment after stroke: frequency of different deficits and their recovery. Clin Rehabil 22(8):758–767. doi:10.1177/0269215508090674 CrossRefPubMed

Conway BA, Halliday DM, Farmer SF, Shahani U, Maas P, Weir AI, Rosenberg JR (1995) Synchronization between motor cortex and spinal motoneuronal pool during the performance of a maintained motor task in man. J Physiol 489(Pt 3):917–924CrossRefPubMedCentralPubMed

De Vos M, Vos DM, Riès S, Vanderperren K, Vanrumste B, Alario FX, Van Huffel S, Huffel VS, Burle B (2010) Removal of muscle artifacts from EEG recordings of spoken language production. Neuroinformatics 8(2):135–150. doi:10.1007/s12021-010-9071-0 CrossRefPubMed

Dobkin BH (2005) Rehabilitation after stroke. N Engl J Med 352(16):1677–1684. doi:10.1056/NEJMcp043511 CrossRefPubMedCentralPubMed

Dukelow SP, Herter TM, Moore KD, Demers MJ, Glasgow JI, Bagg SD, Norman KE, Scott SH (2010) Quantitative assessment of limb position sense following stroke. Neurorehabil Neural Repair 24(2):178–187. doi:10.1177/1545968309345267 CrossRefPubMed

Fries P (2005) A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. Trends Cogn Sci 9(10):474–480. doi:10.1016/j.tics.2005.08.011 CrossRefPubMed

Fugl-Meyer AR, Jääskö L, Leyman I, Olsson S, Steglind S (1975) The post-stroke hemiplegic patient. 1. A method for evaluation of physical performance. Scand J Rehabil Med 7(1):13–31PubMed

Halliday DM, Conway BA, Farmer SF, Rosenberg JR (1998) Using electroencephalography to study functional coupling between cortical activity and electromyograms during voluntary contractions in humans. Neurosci Lett 241(1):5–8CrossRefPubMed

Herrmann CS (2001) Human EEG responses to 1–100 Hz flicker: resonance phenomena in visual cortex and their potential correlation to cognitive phenomena. Exp Brain Res 137(3–4):346–353. doi:10.1007/s002210100682 CrossRefPubMed

Kwakkel G, Kollen BJ, van der Grond J, Prevo AJH (2003) Probability of regaining dexterity in the flaccid upper limb: impact of severity of paresis and time since onset in acute stroke. Stroke 34(9):2181–6. doi:10.1161/01.STR.0000087172.16305.CD CrossRefPubMed

Kwakkel G, Kollen B, Lindeman E (2004) Understanding the pattern of functional recovery after stroke: facts and theories. Restor Neurol Neurosci 22(3–5):281–299PubMed

Lincoln NB, Crow JL, Jackson JM, Waters GR, Adams SA, Hodgson P (1991) The unreliability of sensory assessments. Clin Rehabil 5:273–282. doi:10.1177/026921559100500403 CrossRef

Mendez-Balbuena I, Huethe F, Schulte-Mönting J, Leonhart R, Manjarrez E, Kristeva R (2011) Corticomuscular coherence reflects interindividual differences in the state of the corticomuscular network during low-level static and dynamic forces. Cereb Cortex 22:628–638. doi:10.1093/cercor/bhr147 CrossRefPubMed

Mima T, Steger J, Schulman AE, Gerloff C, Hallett M (2000) Electroencephalographic measurement of motor cortex control of muscle activity in humans. Clin Neurophysiol 111(2):326–337. doi:10.1016/S1388-2457(99)00229-1 CrossRefPubMed

Mima T, Matsuoka T, Hallett M (2001) Information flow from the sensorimotor cortex to muscle in humans. Clin Neurophysiol 112(1):122–126. doi:10.1016/S1388-2457(00)00515-0 CrossRefPubMed

Nijland RHM, van Wegen EEH, Kwakkel G (2010) Presence of finger extension and shoulder abduction within 72 hours after stroke predicts functional recovery: early prediction of functional outcome after stroke: the EPOS cohort study. Stroke 41(4):745–750. doi:10.1161/STROKEAHA.109.572065 CrossRefPubMed

Oostenveld R, Praamstra P (2001) The five percent electrode system for high-resolution EEG and ERP measurements. Clin Neurophysiol 112(4):713–719. doi:10.1016/S1388-2457(00)00527-7 CrossRefPubMed

Oostenveld R, Fries P, Maris E, Schoffelen JM (2011) FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data. Comput Intell Neurosci 2011:156869. doi:10.1155/2011/156869 CrossRefPubMedCentralPubMed

Pohja M, Salenius S (2003) Modulation of cortex-muscle oscillatory interaction by ischaemia-induced deafferentation. Neuroreport 14(3):321–324. doi:10.1097/01.wnr.0000058518.74643.96 CrossRefPubMed

Riddle CN, Baker SN (2005) Manipulation of peripheral neural feedback loops alters human corticomuscular coherence. J Physiol 566(Pt 2):625–639. doi:10.1113/jphysiol.2005.089607 CrossRefPubMedCentralPubMed

Schabrun SM, Hillier S (2009) Evidence for the retraining of sensation after stroke: a systematic review. Clin Rehabil 23(1):27–39. doi:10.1177/0269215508098897 CrossRefPubMed

Scott SH (2004) Optimal feedback control and the neural basis of volitional motor control. Nat Rev Neurosci 5(7):532–546. doi:10.1038/nrn1427 CrossRefPubMed

Serrien DJ, Strens LHA, Cassidy MJ, Thompson AJ, Brown P (2004) Functional significance of the ipsilateral hemisphere during movement of the affected hand after stroke. Exp Neurol 190(2):425–432. doi:10.1016/j.expneurol.2004.08.004 CrossRefPubMed

Severens M, Nienhuis B, Desain P, Duysens J (2012) Feasibility of measuring event related desynchronization with electroencephalography during walking. Annu Int Conf IEEE Eng Med Biol Soc 2012:2764–2767. doi:10.1109/EMBC.2012.6346537

Stolk-Hornsveld F, Crow JL, Hendriks EP, van der Baan R (2006) The Erasmus MC modifications to the (revised) Nottingham Sensory Assessment: a reliable somatosensory assessment measure for patients with intracranial disorders. Clin Rehabil 20(2):160–172. doi:10.1191/0269215506cr932oa CrossRefPubMed

Ushiyama J, Suzuki T, Masakado Y, Hase K, Kimura A, Liu M, Ushiba J (2011) Between-subject variance in the magnitude of corticomuscular coherence during tonic isometric contraction of the tibialis anterior muscle in healthy young adults. J Neurophysiol 106(3):1379–88. doi:10.1152/jn.00193.2011 CrossRefPubMed

Varela F, Lachaux JP, Rodriguez E, Martinerie J (2001) The brainweb: phase synchronization and large-scale integration. Nat Rev Neurosci 2(4):229–239. doi:10.1038/35067550 CrossRefPubMed

Ward NS (2003) Neural correlates of outcome after stroke: a cross-sectional fMRI study. Brain 126(6):1430–1448. doi:10.1093/brain/awg145 CrossRefPubMedCentralPubMed

Williams ER, Soteropoulos DS, Baker SN (2009) Coherence between motor cortical activity and peripheral discontinuities during slow finger movements. J Neurophysiol 102(2):1296–1309. doi:10.1152/jn.90996.2008 CrossRefPubMedCentralPubMed

Witham CL, Riddle CN, Baker MR, Baker SN (2011) Contributions of descending and ascending pathways to corticomuscular coherence in humans. J Physiol 589(Pt 15):3789–3800. doi:10.1113/jphysiol.2011.211045 CrossRefPubMedCentralPubMed

Title: Poor motor function is associated with reduced sensory processing after stroke
Authors: S. Floor Campfens
Sarah B. Zandvliet
Carel G. M. Meskers
Alfred C. Schouten
Michel J. A. M. van Putten
Herman van der Kooij
Publication date: 01-04-2015
Publisher: Springer Berlin Heidelberg
Published in: Experimental Brain Research / Issue 4/2015
Print ISSN: 0014-4819
Electronic ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-015-4206-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Poor motor function is associated with reduced sensory processing after stroke

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2015

Upper limb performance and the structuring of joint movement in teenagers with cerebral palsy: the reciprocal role of task demands and action capabilities

Influence of topical application of capsaicin, menthol and local anesthetics on intraoral somatosensory sensitivity in healthy subjects: temporal and spatial aspects

Distracting visuospatial attention while approaching an obstacle reduces the toe-obstacle clearance

The role of the dorsolateral funiculi in the pain relieving effect of spinal cord stimulation: a study in a rat model of neuropathic pain

The prevalence effect in lateral masking and its relevance for visual search

Corrective jitter motion shows similar individual frequencies for the arm and the finger