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01-01-2022 | Osteoporosis | Original Article

Secular trends of incidence and hospitalization cost of hip fracture in Tangshan, China

Authors: X.-l. Hou, J.-y. Liu, X.-h. Fan, N. Zhang, G.-l. Cao, Z.-b. Guo, Y.-y. Zhang, Y.-h. Yu, Y.-q. Tian, X.-x. Sun, F.-m. Tian

Published in: Osteoporosis International | Issue 1/2022

Abstract

Summary

We investigated the secular trends of the incidence and hospitalization cost of hip fracture in Tangshan, China. The incidence of hip fracture and the hospitalization cost were both increasing during the observation period.

Introduction

The present study aimed to determine sex-, age-, and fracture type-specific incidence and annual changes in hip fractures in Tangshan, China, between 2007 and 2018.

Methods

We analyzed annual hip fracture incidence using urban hospital data during 2007–2018 and calculated incidence rate/100,000 person years in each age group and sex. We assessed annual changes in incidence among people aged >60 years using linear-by-linear association tests and evaluated hospitalization costs with the Kruskal–Wallis test.

Results

During the study period, we observed an increasing proportion of hip fractures in people >60 years old from 14.2 to 22.79%. Crude hip fracture incidence increased markedly from 140.87 to 306.56/100,000 in women (p < 0.01) and from 124.83 to 167.19/100,000 in men (p < 0.01) in the age group >60 years. Type-specific analysis indicated significantly increased trends in incidence of cervical and trochanteric fractures among women and cervical fracture among men (p < 0.01). In people aged 36–60 years, the trend of hip fracture increased significantly in both sexes. The total and cervical-to-trochanteric ratio in men increased, with significant upward trends (p < 0.01). The proportion of cervical fracture was higher than that for trochanteric fracture in women, with stable levels from 2007 to 2018. Hospitalization costs for cervical and trochanteric fractures increased by 51.91% and 53.20%, respectively, during 2011–2018.

Conclusion

Tangshan will have an increasing burden on health care resources attributable to a considerable rise in hip fracture incidence and the older population. Further investigation of risk factors and subsequent implementation of effective measures to prevent hip fracture are needed.

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Gu Y, Chen X, Wang Y et al (2020) Development of 3-mercaptopropyltrimethoxy-silane (MPTS)-modified bone marrow mononuclear cell membrane chromatography for screening anti-osteoporosis components from Scutellariae Radix. Acta Pharm Sin 10:1856–1865. https://doi.org/10.1016/j.apsb.2020.01.019CrossRef

Akhtar MN, Gon S, Sen B et al (2020) Unveiling the metabolic mystery of fragility hip fracture in Indian patients: a histomorphometric and biochemical correlation. Indian J Orthop 54:297–306. https://doi.org/10.1007/s43465-020-00253-wCrossRefPubMedPubMedCentral

Hori K, Siu AM, Nguyen ET, Andrews SN, Choi SY, Ahn HJ, Nakasone CK, Lim SY (2020) Osteoporotic hip fracture mortality and associated factors in Hawai’i. Arch Osteoporos 1:183–192. https://doi.org/10.1007/s11657-020-00847-9CrossRef

Veronese N, Maggi S (2018) Epidemiology and social costs of hip fracture. Injury 49:1458–1460. https://doi.org/10.1016/j.injury.2018.04.015CrossRefPubMed

Yu A, Carballido-Gamio J, Wang L (2017) Spatial differences in the distribution of bone between femoral neck and trochanteric fractures. J Bone Miner Res 32:1672–1680. https://doi.org/10.1002/jbmr.3150CrossRefPubMed

Mattisson L, Bojan A, Enocson A (2018) Epidemiology, treatment and mortality of trochanteric and subtrochanteric hip fractures: data from the Swedish fracture register. BMC Musculoskelet Disord 19:369–377. https://doi.org/10.1186/s12891-018-2276-3CrossRefPubMedPubMedCentral

Clark P, Lavielle P, Franco-Marina F, Ramírez E, Salmerón J, Kanis JA, Cummings SR (2005) Incidence rates and life-time risk of hip fractures in Mexicans over 50 years of age: a population-based. Osteoporos Int 16:2025–2030. https://doi.org/10.1007/s00198-005-1991-4CrossRefPubMed

Icks A, Arend W, Becker C, Rapp K, Jungbluth P, Haastert B (2013) Incidence of hip fractures in Germany, 1995-2010. Arch Osteoporos 8:140–147. https://doi.org/10.1007/s11657-013-0140-5CrossRefPubMed

Xia WB, He SL, Xu L, Liu AM, Jiang Y, Li M, Wang O, Xing XP, Sun Y, Cummings SR (2012) Rapidly increasing rates of hip fracture in Beijing, China. J Bone Miner Res 27:125–129. https://doi.org/10.1002/jbmr.519CrossRefPubMed

10.

Imai N, Endo N, Shobugawa Y, Ibuchi S, Suzuki H, Miyasaka D, Sakuma M (2017) A decrease in the number and incidence of osteoporotic hip fractures among elderly individuals in Niigata, Japan, from 2010 to 2015. J Bone Miner Metab 36:573–579. https://doi.org/10.1007/s00774-017-0863-2CrossRefPubMed

11.

Tan LT, Wong SJ, Kwek EB (2017) Inpatient cost for hip fracture patients managed with an orthogeriatric care model in Singapore. Singapore Med J Mar 58(3):139–144. https://doi.org/10.11622/smedj.2016065CrossRef

12.

Tian FM, Sun XX, Liu JY, Liu ZK, Liang CY, Zhang L (2017) Unparallel gender-specific changes in the incidence of hip fractures in Tangshan, China. Arch Osteoporos 12:18–25. https://doi.org/10.1007/s11657-017-0313-8CrossRefPubMed

13.

Michaelsson K, Weiderpass E, Farahmand B et al (1999) Differences in risk factor patterns between cervical and trochanteric hip fractures. Osteoporos Int 10:487–494. https://doi.org/10.1007/s001980050259CrossRefPubMed

14.

Gao J, Zheng Q, Lai FY, Gartner C, du P, Ren Y, Li X, Wang D, Mueller JF, Thai PK (2020) Using wastewater-based epidemiology to estimate consumption of alcohol and nicotine in major cities of China in 2014 and 2016. Environ Int 136:105492. https://doi.org/10.1016/j.envint.2020.105492CrossRefPubMed

15.

Berg KM, Kunins HV, Jackson JL et al (2007) Association between alcohol consumption and both osteoporotic fracture and bone density. Am J Med 121:406–418. https://doi.org/10.1016/j.amjmedCrossRef

16.

Mautalen CA, Vega EM, Einhorn TA (1996) Are the etiologies of cervical and trochanteric hip fractures different? Bone 18:133S- 137S. https://doi.org/10.1016/8756-3282(95)00490-4, 18, S133, S137

17.

Jokinen H, Pulkkinen P, Korpelainen J, Heikkinen J, Keinänen-Kiukaanniemi S, Jämsä T, Korpelainen R (2020) Risk factors for cervical and trochanteric hip fractures in elderly women: a population-based 10-year follow-up study. Calcif Tissue Int 87:44–51. https://doi.org/10.1007/s00223-010-9382-zCrossRef

18.

Schott AM, Hans D, Duboeuf F, Dargent-Molina P, Hajri T, Bréart G, Meunier PJ, EPIDOS Study Group (2005) Quantitative ultrasound parameters as well as bone mineral density are better predictors of trochanteric than cervical hip fractures in elderly women. Results from the EPIDOS study Bone 37:858–863. https://doi.org/10.1016/j.bone.2005.06.024CrossRefPubMed

19.

Hernández JL, Olmos JM, Alonso MA, González-Fernández CR, Martínez J, Pajarón M, Llorca J, González-Macías J (2006) Trend in hip fracture epidemiology over a 14-year period in a Spanish population. Osteoporos Int 17:464–470. https://doi.org/10.1007/s00198-005-0008-7CrossRefPubMed

20.

Lim J (2020) Big data-driven determinants of length of stay for patients with hip fracture. Int J Environ Res Public Health 17:4949–4958. https://doi.org/10.3390/ijerph17144949CrossRefPubMedPubMedCentral

21.

Caminiti C, Meschi T, Braglia L, Diodati F, Iezzi E, Marcomini B, Nouvenne A, Palermo E, Prati B, Schianchi T, Borghi L (2013) Reducing unnecessary hospital days to improve quality of care through physician accountability: a cluster randomised trial. BMC Health Serv Res 13:14–23. https://doi.org/10.1186/1472-6963-13-14CrossRefPubMedPubMedCentral

22.

Aletto C, Aicale R, Pezzuti G, Bruno F, Maffulli N (2020) Impact of an orthogeriatrician on length of stay of elderly patient with hip fracture. Osteoporos Int 31:2161–2166. https://doi.org/10.1007/s00198-020-05510-0CrossRefPubMed

23.

Shojania KG, Duncan BW, McDonald KM et al (2002) Safe but sound: patient safety meets evidence-based medicine. JAMA 2884:508–513. https://doi.org/10.1001/jama.288.4.508CrossRef

24.

China Health Promotion Foundation (2008) White paper China osteoporosis a summary statement of China, Beijing

25.

Si L, Winzenberg TM, Jiang Q et al (2015) Projection of osteoporosis-related fractures and costs in China: 2010-2050. Osteoporos Int 26:1929–1937. https://doi.org/10.1007/s00198-015-3093-2CrossRefPubMed

26.

Lin X, Xiong D, Peng YQ et al (2015) Epidemiology and management of osteoporosis in the People’s Republic of China: current perspectives. Clin Interv Aging 10:1017–1033. https://doi.org/10.2147/CIA.S54613CrossRefPubMedPubMedCentral

27.

Wang YL, Cui HR, Zhang DY, Zhang P (2018) Hospitalization cost analysis on hip fracture in China: a multicentre study among 73 tertiary hospitals. BMJ Open 8:e019147. https://doi.org/10.1136/bmjopen-2017-019147CrossRefPubMedPubMedCentral

Title: Secular trends of incidence and hospitalization cost of hip fracture in Tangshan, China
Authors: X.-l. Hou
J.-y. Liu
X.-h. Fan
N. Zhang
G.-l. Cao
Z.-b. Guo
Y.-y. Zhang
Y.-h. Yu
Y.-q. Tian
X.-x. Sun
F.-m. Tian
Publication date: 01-01-2022
Publisher: Springer London
Keywords: Osteoporosis
Osteoporosis
Published in: Osteoporosis International / Issue 1/2022
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-021-06050-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Secular trends of incidence and hospitalization cost of hip fracture in Tangshan, China

Abstract

Summary

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Summary

Introduction

Methods

Results

Conclusion

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