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Osteoporosis International

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Open Access 01-03-2017 | Original Article

Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France

Authors: M. Hiligsmann, N. Burlet, P. Fardellone, N. Al-Daghri, J.-Y. Reginster

Published in: Osteoporosis International | Issue 3/2017

Abstract

Summary

The recommended intake of vitamin D-fortified dairy products can substantially decrease the burden of osteoporotic fractures and seems an economically beneficial strategy in the general French population aged over 60 years.

Introduction

This study aims to assess the public health and economic impact of vitamin D-fortified dairy products in the general French population aged over 60 years.

Methods

We estimated the lifetime health impacts expressed in number of fractures prevented, life years gained, and quality-adjusted life years (QALY) gained of the recommended intake of dairy products in the general French population over 60 years for 1 year (2015). A validated microsimulation model was used to simulate three age cohorts for both women and men (60–69, 70–79, and >80 years). The incremental cost per QALY gained of vitamin D-fortified dairy products compared to the absence of appropriate intake was estimated in different populations, assuming the cost of two dairy products per day in base case.

Results

The total lifetime number of fractures decreased by 64,932 for the recommended intake of dairy products in the general population over 60 years, of which 46,472 and 18,460 occurred in women and men, respectively. In particular, 15,087 and 4413 hip fractures could be prevented in women and men. Vitamin D-fortified dairy products also resulted in 32,569 QALYs and 29,169 life years gained. The cost per QALY gained of appropriate dairy intake was estimated at €58,244 and fall below a threshold of €30,000 per QALY gained in women over 70 years and in men over 80 years.

Conclusion

Vitamin D-fortified dairy products have the potential to substantially reduce the burden of osteoporotic fractures in France and seem an economically beneficial strategy, especially in the general population aged above 70 years.

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Title: Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France
Authors: M. Hiligsmann
N. Burlet
P. Fardellone
N. Al-Daghri
J.-Y. Reginster
Publication date: 01-03-2017
Publisher: Springer London
Published in: Osteoporosis International / Issue 3/2017
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-016-3786-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Public health impact and economic evaluation of vitamin D-fortified dairy products for fracture prevention in France

Abstract

Summary

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Summary

Introduction

Methods

Results

Conclusion

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