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Published in: Osteoporosis International 5/2013

01-05-2013 | Case Report

A case of an atypical femoral fracture associated with bacterial biofilm—pathogen or bystander?

Authors: T. S. Howe, G. Erlich, J. S. B. Koh, A. C. M. Ng, W. Costerton

Published in: Osteoporosis International | Issue 5/2013

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Abstract

We report a case of an 86-year-old woman with an atypical femoral fracture (AFF) who was treated with intramedullary nailing followed by lateral femoral plating. She developed a second femoral shaft fracture distal to the intramedullary nail which required a second operation. Biopsy of the periosteum overlying the site of the initial proximal AFF was sent for pathogen analysis. Using the Ibis T5000 platform and the BAC plate assay, a polymicrobial infection was diagnosed consisting of Bifidobacterium subtile and Pseudomonas mendocina. This raises the possibility that bacterial infections may play some role in atypical fractures of the femur.
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Metadata
Title
A case of an atypical femoral fracture associated with bacterial biofilm—pathogen or bystander?
Authors
T. S. Howe
G. Erlich
J. S. B. Koh
A. C. M. Ng
W. Costerton
Publication date
01-05-2013
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 5/2013
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-012-2222-4

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