Skip to main content
Top
Published in: Osteoporosis International 10/2007

01-10-2007 | Original Article

Back extensor strength and lumbar spinal mobility are predictors of quality of life in patients with postmenopausal osteoporosis

Authors: N. Miyakoshi, M. Hongo, S. Maekawa, Y. Ishikawa, Y. Shimada, E. Itoi

Published in: Osteoporosis International | Issue 10/2007

Login to get access

Abstract

Summary

To assess the effect of multiple factors on quality of life (QOL) in osteoporosis, relationships between the QOL and possible spinal factors were analyzed in 174 postmenopausal women with osteoporosis. Back extensor strength and lumbar spinal mobility were the most important factors for QOL in these patients.

Introduction

Quality of life (QOL) in patients with osteoporosis and vertebral fractures is impaired by the decline of total spinal mobility, although it is not clear to what extent. This study aimed to assess the effect of multiple factors on QOL in patients with osteoporosis.

Methods

QOL of 174 postmenopausal women with osteoporosis (mean, 68 years old) was evaluated using the Japanese Osteoporosis QOL Questionnaire (JOQOL). Correlations between the JOQOL score, bone mineral density (BMD) of the lumbar spine/proximal femur/whole body, the kyphosis angle and mobility of thoracic and lumbar spine, the number of vertebral fractures, grip strengths of dominant and non-dominant hands, and isometric back extensor strength (BES) were analyzed.

Results

JOQOL showed significant correlation (p < 0.05) with age (r = −0.303), BES (r = 0.455), dominant and non-dominant grip strengths (r = 0.273 and r = 0.255, respectively), number of vertebral fractures (r = −0.282), BMDs of proximal femur and whole body (r = 0.200 and r = 0.157, respectively), lumbar kyphosis angle (r = −0.296), and lumbar spinal mobility (r = 0.345). Multiple regression analysis revealed that the BES and lumbar spinal mobility were the significant contributors to the JOQOL (p < 0.05).

Conclusion

BES and lumbar spinal mobility are the important factors for QOL in patients with postmenopausal osteoporosis.
Literature
1.
go back to reference Nevitt MC, Ettinger B, Black DM et al (1998) The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med 128:793–800PubMed Nevitt MC, Ettinger B, Black DM et al (1998) The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med 128:793–800PubMed
2.
go back to reference Martin AR, Sornay-Rendu E, Chandler JM et al (2002) The impact of osteoporosis on quality-of-life: the OFELY cohort. Bone 31:32–36PubMedCrossRef Martin AR, Sornay-Rendu E, Chandler JM et al (2002) The impact of osteoporosis on quality-of-life: the OFELY cohort. Bone 31:32–36PubMedCrossRef
3.
go back to reference Miyakoshi N, Itoi E, Kobayashi M et al (2003) Impact of postural deformities and spinal mobility on quality of life in postmenopausal osteoporosis. Osteoporos Int 14:1007–1012PubMedCrossRef Miyakoshi N, Itoi E, Kobayashi M et al (2003) Impact of postural deformities and spinal mobility on quality of life in postmenopausal osteoporosis. Osteoporos Int 14:1007–1012PubMedCrossRef
4.
go back to reference Nicholas J, Wilson P (1963) Osteoporosis of the aged spine. Clin Orthop 26:19–33PubMed Nicholas J, Wilson P (1963) Osteoporosis of the aged spine. Clin Orthop 26:19–33PubMed
5.
go back to reference Ryan S, Fried L (1997) The impact of kyphosis on daily functioning. J Am Gerontol Soc 45:1479–1486 Ryan S, Fried L (1997) The impact of kyphosis on daily functioning. J Am Gerontol Soc 45:1479–1486
6.
go back to reference Adachi JD, Ioannidis G, Berger C et al (2001) The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada. Osteoporos Int 12:903–908PubMedCrossRef Adachi JD, Ioannidis G, Berger C et al (2001) The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada. Osteoporos Int 12:903–908PubMedCrossRef
7.
go back to reference Adachi JD, Ioannidis G, Olszynski WP et al (2002) The impact of incident vertebral and non-vertebral fractures on health related quality of life in postmenopausal women. BMC Musculoskelet Disord 3:11PubMedCrossRef Adachi JD, Ioannidis G, Olszynski WP et al (2002) The impact of incident vertebral and non-vertebral fractures on health related quality of life in postmenopausal women. BMC Musculoskelet Disord 3:11PubMedCrossRef
8.
go back to reference Lips P, Cooper C, Agnusdei D et al (1997) Quality of life as outcome in the treatment of osteoporosis: the development of a questionnaire for quality of life by the European Foundation for Osteoporosis. Osteoporos Int 7:36–38PubMedCrossRef Lips P, Cooper C, Agnusdei D et al (1997) Quality of life as outcome in the treatment of osteoporosis: the development of a questionnaire for quality of life by the European Foundation for Osteoporosis. Osteoporos Int 7:36–38PubMedCrossRef
9.
go back to reference Lips P, Cooper C, Agnusdei D et al (1999) Quality of life in patients with vertebral fractures: validation of the quality of life questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Osteoporos Int 10:150–160PubMedCrossRef Lips P, Cooper C, Agnusdei D et al (1999) Quality of life in patients with vertebral fractures: validation of the quality of life questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Osteoporos Int 10:150–160PubMedCrossRef
10.
go back to reference Oleksik A, Lips P, Dawson A et al (2000) Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 15:1384–1392PubMedCrossRef Oleksik A, Lips P, Dawson A et al (2000) Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 15:1384–1392PubMedCrossRef
11.
go back to reference Silverman SL, Minshall ME, Shen W et al (2001) The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. Arthritis Rheum 44:2611–2619PubMedCrossRef Silverman SL, Minshall ME, Shen W et al (2001) The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. Arthritis Rheum 44:2611–2619PubMedCrossRef
12.
go back to reference Silverman SL, Piziak VK, Chen P et al (2005) Relationship of health related quality of life to prevent and new or worsening back pain in postmenopausal women with osteoporosis. J Rheumatol 32:2405–2409PubMed Silverman SL, Piziak VK, Chen P et al (2005) Relationship of health related quality of life to prevent and new or worsening back pain in postmenopausal women with osteoporosis. J Rheumatol 32:2405–2409PubMed
13.
go back to reference Johnell O, Oden A, Caulin F et al (2001) Acute and long-term increase in fracture risk after hospitalization for vertebral fracture. Osteoporos Int 12:207–214PubMedCrossRef Johnell O, Oden A, Caulin F et al (2001) Acute and long-term increase in fracture risk after hospitalization for vertebral fracture. Osteoporos Int 12:207–214PubMedCrossRef
14.
go back to reference Lindsay R, Silverman SL, Cooper C et al (2001) Risk of new vertebral fracture in the year following a fracture. JAMA 285:320–323PubMedCrossRef Lindsay R, Silverman SL, Cooper C et al (2001) Risk of new vertebral fracture in the year following a fracture. JAMA 285:320–323PubMedCrossRef
15.
go back to reference Naves M, Diaz-Lopez JB, Gomez C et al (2003) The effect of vertebral fracture as a risk factor for osteoporotic fracture and mortality in a Spanish population. Osteoporos Int 14:520–524PubMedCrossRef Naves M, Diaz-Lopez JB, Gomez C et al (2003) The effect of vertebral fracture as a risk factor for osteoporotic fracture and mortality in a Spanish population. Osteoporos Int 14:520–524PubMedCrossRef
16.
go back to reference Cooper C, Atkinson EJ, Jacobsen SJ et al (1993) Population-based study of survival after osteoporotic fractures. Am J Epidemiol 137:1001–1005PubMed Cooper C, Atkinson EJ, Jacobsen SJ et al (1993) Population-based study of survival after osteoporotic fractures. Am J Epidemiol 137:1001–1005PubMed
17.
go back to reference Kado DM, Duong T, Stone KL et al (2003) Incident vertebral fractures and mortality in older women: a prospective study. Osteoporos Int 14:589–594PubMedCrossRef Kado DM, Duong T, Stone KL et al (2003) Incident vertebral fractures and mortality in older women: a prospective study. Osteoporos Int 14:589–594PubMedCrossRef
18.
go back to reference Miyakoshi N, Hongo M, Maekawa S et al (2005) Factors related to spinal mobility in patients with postmenopausal osteoporosis. Osteoporos Int 16:1871–1874PubMedCrossRef Miyakoshi N, Hongo M, Maekawa S et al (2005) Factors related to spinal mobility in patients with postmenopausal osteoporosis. Osteoporos Int 16:1871–1874PubMedCrossRef
19.
go back to reference Orimo H, Shiraki M, Hayashi Y et al (1994) Effects of 1α-hydroxyvitamin D3 on lumbar bone mineral density and vertebral fractures in patients with postmenopausal osteoporosis. Calcif Tissue Int 54:370–376PubMedCrossRef Orimo H, Shiraki M, Hayashi Y et al (1994) Effects of 1α-hydroxyvitamin D3 on lumbar bone mineral density and vertebral fractures in patients with postmenopausal osteoporosis. Calcif Tissue Int 54:370–376PubMedCrossRef
20.
go back to reference Shimada T (1996) Factors affecting appearance patterns of hip-flexion contractures and their effects on postural and gait abnormalities. Kobe J Med Sci 42:271–290PubMed Shimada T (1996) Factors affecting appearance patterns of hip-flexion contractures and their effects on postural and gait abnormalities. Kobe J Med Sci 42:271–290PubMed
21.
go back to reference Takahashi H, Iwaya C, Iba K et al (2001) The Japanese Osteoporosis QOL Questionnaire (JOQOL): 2000 edition. J Jpn Soc Bone Miner Res 18:85–101, (in Japanese) Takahashi H, Iwaya C, Iba K et al (2001) The Japanese Osteoporosis QOL Questionnaire (JOQOL): 2000 edition. J Jpn Soc Bone Miner Res 18:85–101, (in Japanese)
22.
go back to reference Randell AG, Bhalerao N, Nguyen TV et al (1998) Quality of life in osteoporosis: reliability, consistency, and validity of the Osteoporosis Assessment Questionnaire. J Rheum 25:1171–1179PubMed Randell AG, Bhalerao N, Nguyen TV et al (1998) Quality of life in osteoporosis: reliability, consistency, and validity of the Osteoporosis Assessment Questionnaire. J Rheum 25:1171–1179PubMed
23.
go back to reference Miyakoshi N, Itoi E, Murai H et al (2003) Inverse relation between osteoporosis and spondylosis in postmenopausal women as evaluated by bone mineral density and semiquantitative scoring of spinal degeneration. Spine 28:492–495PubMedCrossRef Miyakoshi N, Itoi E, Murai H et al (2003) Inverse relation between osteoporosis and spondylosis in postmenopausal women as evaluated by bone mineral density and semiquantitative scoring of spinal degeneration. Spine 28:492–495PubMedCrossRef
24.
go back to reference Post RB, Leferink VJ (2004) Spinal mobility: sagittal range of motion measured with the SpinalMouse, a new non-invasive device. Arch Orthop Trauma Surg 124:187–192PubMedCrossRef Post RB, Leferink VJ (2004) Spinal mobility: sagittal range of motion measured with the SpinalMouse, a new non-invasive device. Arch Orthop Trauma Surg 124:187–192PubMedCrossRef
25.
go back to reference Kanagae M, Abe Y, Honda S et al (2006) Determinants of self-rated health among community-dwelling women aged 40 years and over in Japan. Tohoku J Exp Med 210:11–19PubMedCrossRef Kanagae M, Abe Y, Honda S et al (2006) Determinants of self-rated health among community-dwelling women aged 40 years and over in Japan. Tohoku J Exp Med 210:11–19PubMedCrossRef
26.
go back to reference Limburg PJ, Sinaki M, Rogers JW et al (1991) A useful technique for measurement of back strength in osteoporotic and elderly patients. Mayo Clin Proc 66:39–44PubMed Limburg PJ, Sinaki M, Rogers JW et al (1991) A useful technique for measurement of back strength in osteoporotic and elderly patients. Mayo Clin Proc 66:39–44PubMed
27.
go back to reference Burger H, VanDaele PLA, Grashuis K et al (1997) Vertebral deformities and functional impairment in men and women. J Bone Miner Res 12:152–157PubMedCrossRef Burger H, VanDaele PLA, Grashuis K et al (1997) Vertebral deformities and functional impairment in men and women. J Bone Miner Res 12:152–157PubMedCrossRef
28.
go back to reference Huang C, Ross PD, Wasnich RD (1996) Vertebral fracture and other predictors of physical impairment and health care utilization. Arch Intern Med 15:2469–2475CrossRef Huang C, Ross PD, Wasnich RD (1996) Vertebral fracture and other predictors of physical impairment and health care utilization. Arch Intern Med 15:2469–2475CrossRef
29.
go back to reference Lyles KW, Gold DT, Shipp KM et al (1993) Association of osteoporosis vertebral compression fractures with impaired functional status. Am J Med 94:595–601PubMedCrossRef Lyles KW, Gold DT, Shipp KM et al (1993) Association of osteoporosis vertebral compression fractures with impaired functional status. Am J Med 94:595–601PubMedCrossRef
30.
go back to reference Kado DM, Huang MH, Barrett-Connor E et al (2005) Hyperkyphotic posture and poor physical functional ability in older community-dwelling men and women: the Rancho Bernardo study. J Gerontol A Biol Sci Med Sci 60:633–637PubMed Kado DM, Huang MH, Barrett-Connor E et al (2005) Hyperkyphotic posture and poor physical functional ability in older community-dwelling men and women: the Rancho Bernardo study. J Gerontol A Biol Sci Med Sci 60:633–637PubMed
31.
go back to reference Sinaki M, Brey RH, Hughes CA et al (2005) Balance disorder and increased risk of falls in osteoporosis and kyphosis: significance of kyphotic posture and muscle strength. Osteoporos Int 16:1004–1010PubMedCrossRef Sinaki M, Brey RH, Hughes CA et al (2005) Balance disorder and increased risk of falls in osteoporosis and kyphosis: significance of kyphotic posture and muscle strength. Osteoporos Int 16:1004–1010PubMedCrossRef
32.
go back to reference Lee CS, Lee CK, Kim YT et al (2001) Dynamic sagittal imbalance of the spine in degenerative flat back: significance of pelvic tilt in surgical treatment. Spine 26:2029–2035PubMedCrossRef Lee CS, Lee CK, Kim YT et al (2001) Dynamic sagittal imbalance of the spine in degenerative flat back: significance of pelvic tilt in surgical treatment. Spine 26:2029–2035PubMedCrossRef
33.
go back to reference Fink HA, Ensrud KE, Nelson DB et al (2003) Disability after clinical fracture in postmenopausal women with low bone density: the fracture intervention trial (FIT). Osteoporos Int 14:69–76PubMedCrossRef Fink HA, Ensrud KE, Nelson DB et al (2003) Disability after clinical fracture in postmenopausal women with low bone density: the fracture intervention trial (FIT). Osteoporos Int 14:69–76PubMedCrossRef
34.
go back to reference Maughan RJ (2005) The limits of human athletic performance. Ann Transplant 10:52–54PubMed Maughan RJ (2005) The limits of human athletic performance. Ann Transplant 10:52–54PubMed
35.
go back to reference Marras WS, Jorgensen MJ, Granata KP et al (2001) Female and male trunk geometry: size and prediction of the spine loading trunk muscles derived from MRI. Clin Biomech (Bristol, Avon) 16:38–46CrossRef Marras WS, Jorgensen MJ, Granata KP et al (2001) Female and male trunk geometry: size and prediction of the spine loading trunk muscles derived from MRI. Clin Biomech (Bristol, Avon) 16:38–46CrossRef
36.
go back to reference Takemitsu Y, Harada Y, Iwahara T et al (1988) Lumbar degenerative kyphosis. Clinical, radiological and epidemiological studies. Spine 13:1317–1326PubMedCrossRef Takemitsu Y, Harada Y, Iwahara T et al (1988) Lumbar degenerative kyphosis. Clinical, radiological and epidemiological studies. Spine 13:1317–1326PubMedCrossRef
37.
go back to reference Sinaki M, Itoi E, Wahner HW et al (2002) Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women. Bone 30:836–841PubMedCrossRef Sinaki M, Itoi E, Wahner HW et al (2002) Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women. Bone 30:836–841PubMedCrossRef
Metadata
Title
Back extensor strength and lumbar spinal mobility are predictors of quality of life in patients with postmenopausal osteoporosis
Authors
N. Miyakoshi
M. Hongo
S. Maekawa
Y. Ishikawa
Y. Shimada
E. Itoi
Publication date
01-10-2007
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 10/2007
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-007-0383-3

Other articles of this Issue 10/2007

Osteoporosis International 10/2007 Go to the issue