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Published in: Osteoporosis International 6/2005

01-06-2005 | Review

Assessment of fracture risk

Authors: John A. Kanis, Frederik Borgstrom, Chris De Laet, Helena Johansson, Olof Johnell, Bengt Jonsson, Anders Oden, Niklas Zethraeus, Bruce Pfleger, Nikolai Khaltaev

Published in: Osteoporosis International | Issue 6/2005

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Abstract

The diagnosis of osteoporosis is based on the measurement of bone mineral density (BMD). There are a number of clinical risk factors that provide information on fracture risk over and above that given by BMD. The assessment of fracture risk thus needs to be distinguished from diagnosis to take account of the independent value of the clinical risk factors. These include age, a prior fragility fracture, a parental history of hip fracture, smoking, use of systemic corticosteroids, excess alcohol intake and rheumatoid arthritis. The independent contribution of these risk factors can be integrated by the calculation of fracture probability with or without the use of BMD. Treatment can then be offered to those identified to have a fracture probability greater than an intervention threshold.
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Metadata
Title
Assessment of fracture risk
Authors
John A. Kanis
Frederik Borgstrom
Chris De Laet
Helena Johansson
Olof Johnell
Bengt Jonsson
Anders Oden
Niklas Zethraeus
Bruce Pfleger
Nikolai Khaltaev
Publication date
01-06-2005
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 6/2005
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-004-1780-5

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