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01-03-2019 | Hydroxychloroquine | Editorial

Chronic use of pentosan polysulfate sodium associated with risk of vision-threatening disease

Authors: Tanner J. Ferguson, Ryan L. Geraets, Matthew A. Barker

Published in: International Urogynecology Journal | Issue 3/2019

Excerpt

A recent article in Ophthalmology in May 2018 by Pearce et al. uncovered a potential vision-threatening complication associated with the long-term use of pentosane polysulfate sodium (PPS), an established treatment for interstitial cystitis and the only FDA-approved oral option, sold under the brand name Elmiron [1]. The authors should be commended for their work and we encourage the review of their initial report [2]. …

Kivlin D, Lim C, Ross C, Whitmore K, Schellato T. The diagnostic and treatment patterns of urologists in the United States for interstitial cystitis/painful bladder syndrome. Urol Pract. 2016;3(4):309–14. https://doi.org/10.1016/j.urpr.2015.08.005.CrossRef

Pearce WA, Chen R, Jain N. Pigmentary maculopathy associated with chronic exposure to pentosan polysulfate sodium. Ophthalmology. 2018;125(11):1793–802. https://doi.org/10.1016/j.ophtha.2018.04.026.CrossRefPubMed

Pearce WA, Hanif AM, Jain N. Re: FDA BRUDAC 2018 criteria for interstitial cystitis/bladder pain syndrome clinical trials: future direction for research: J C Nickel and R Moldwin J Urol 2018;200:39–42. J Urol. 2018;200(5):1122–3. https://doi.org/10.1016/j.juro.2018.06.076.CrossRefPubMed

Marmor MF, Kellner U, Lai TYY, Melles RB, Mieler WF. American Academy of Ophthalmology. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy (2016 revision). Ophthalmology. 2016;123(6):1386–94. https://doi.org/10.1016/j.ophtha.2016.01.058. CrossRefPubMed

Nickel JC, Barkin J, Forrest J, et al. Randomized, double-blind, dose-ranging study of pentosan polysulfate sodium for interstitial cystitis. Urology. 2005;65(4):654–8. https://doi.org/10.1016/j.urology.2004.10.071.CrossRefPubMed

Title: Chronic use of pentosan polysulfate sodium associated with risk of vision-threatening disease
Authors: Tanner J. Ferguson
Ryan L. Geraets
Matthew A. Barker
Publication date: 01-03-2019
Publisher: Springer International Publishing
Keyword: Hydroxychloroquine
Published in: International Urogynecology Journal / Issue 3/2019
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-018-3850-9

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Chronic use of pentosan polysulfate sodium associated with risk of vision-threatening disease

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Keynote webinar | Spotlight on medication adherence

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