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International Urogynecology Journal

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01-12-2010 | Original Article

Biomechanical properties of prolapsed or non-prolapsed vaginal tissue: impact on genital prolapse surgery

Authors: Clay Jean-Charles, Chrystèle Rubod, Mathias Brieu, Malik Boukerrou, Jean Fasel, Michel Cosson

Published in: International Urogynecology Journal | Issue 12/2010

Abstract

Introduction and hypothesis

Our aim is to characterize prolapsed and non-prolapsed vaginal tissue, and thus offer a better understanding of the genital prolapse physiopathology and an improvement of surgical treatments.

Methods

Vaginal tissue was collected in 30 patients with prolapse (POP) and ten fresh cadavers without prolapse (nPOP) with a favorable advice of Ethics Committee. Uniaxial tension tests were performed. Statistical comparisons of rigidity under moderate deformation and under large deformation have been performed

Results

POP is significantly stiffer than nPOP tissue, both on anterior and posterior walls. A significant difference between POP and nPOP tissues was highlighted when anterior or posterior vaginal walls were respectively compared.

Conclusions

These results might explain the higher rate of relapse when repair is autologous, using already defective and more rigid vaginal tissue. This study suggests that it might be interesting to adapt the characteristics of prosthetic implants to the vaginal face concerned by the prolapsus.

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Title: Biomechanical properties of prolapsed or non-prolapsed vaginal tissue: impact on genital prolapse surgery
Authors: Clay Jean-Charles
Chrystèle Rubod
Mathias Brieu
Malik Boukerrou
Jean Fasel
Michel Cosson
Publication date: 01-12-2010
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 12/2010
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-010-1208-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Biomechanical properties of prolapsed or non-prolapsed vaginal tissue: impact on genital prolapse surgery

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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