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International Urogynecology Journal

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01-09-2010 | Original Article

Evaluating the porcine dermis graft InteXen® in three-compartment transvaginal pelvic organ prolapse repair

Authors: Rajeev Ramanah, Julian Mairot, Marie-Caroline Clement, Bernard Parratte, Robert Maillet, Didier Riethmuller

Published in: International Urogynecology Journal | Issue 9/2010

Abstract

Introduction and hypothesis

The aim was to assess the efficacy of three-compartment pelvic organ prolapse (POP) vaginal repair using the InteXen® biocompatible porcine dermal graft as compared to traditional colporrhaphy with sacrospinous ligament suspension.

Methods

Preoperative, operative, postoperative and follow-up data were collected retrospectively. Objective recurrence was defined as POP quantification ≥ stage II and subjective recurrence as a symptomatic bulge.

Results

Each group consisted of 63 patients. Surgery time was longer using InteXen® (72 ± 24.5 vs 55 ± 23.5 min, p = 0.0002). Length of hospital stay (4.6 ± 1.6 vs 4.9 ± 2.1 days, p = 0.34) as well as duration of follow-up (37.1 vs 35.7 months, p = 0.45) were equivalent between the two groups. No case of mesh erosion or infection was noted. The objective (17% vs 8%, p = 0.12) and subjective recurrence rates (13% vs 5%, p = 0.12) between the two groups were not statistically different.

Conclusions

InteXen® was well tolerated but had similar efficacy to traditional colporrhaphy and sacrospinous ligament suspension.

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Title: Evaluating the porcine dermis graft InteXen® in three-compartment transvaginal pelvic organ prolapse repair
Authors: Rajeev Ramanah
Julian Mairot
Marie-Caroline Clement
Bernard Parratte
Robert Maillet
Didier Riethmuller
Publication date: 01-09-2010
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 9/2010
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-010-1153-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Evaluating the porcine dermis graft InteXen® in three-compartment transvaginal pelvic organ prolapse repair

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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